Gas turbine blades are exposed to high-temperature degradation environments due to flames and mechanical loads as a results of high-speed rotation during operation. In addition, blades are exposed to thermo-mechanical fatigue due to frequent start and shutdown. Therefore, it is necessary to evaluate the lifetime of blade materials.In this study, the TMF life of a Ni-base superalloy applied to gas turbine blade was predicted based on LCF and TMF test results. The LCF tests were conducted under various strain ranges based on gas turbine operating conditions. In addition, IP (in-phase) and OP (out of-phase) TMF tests were conducted under various strain ranges.Finally, a fatigue life prediction model was drawn from the LCF and TMF test results. The correlation between the LCF and TMF test results was also evaluated with respect to fatigue life.