Risk of heart attack is a global issue. This paper attempts to mathematically model the influence of eleven predictors on the heart attack risk. The contribution of each predictor and the related risk of heart attack are obtained from a group of medical doctors. Total 300 such cases are structured in a 300 * 12 matrix to conduct the study. Using statistical data mining, significant joint predictors have been extracted and clinically validated. The study also measures the variations in interpretations among doctors.