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Telomeres, the protective structures at the outmost ends of chromosomes, shorten in all somatic cells with each cell-division and by cumulative oxidative damage. To counteract that these shortened telomeres are passed on to offspring, the telomeres are elongated by the enzyme, telomerase, during human spermatogenesis. A few groups have tried to elucidate this process by measuring telomerase activity...
To provide an evidence-based guideline for professionals working with XY women.Review including patient cases from a Danish fertility clinic.University-associated scientific unit and fertility clinic.Three selected cases.None.Evaluation of etiology, diagnosis, treatment, and associated disorders in XY women.Many gene mutations can cause abnormal fetal development leading to androgen insensitivity...
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