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Loss of expression of apoptotic regulatory proteins in many neoplasias might result in defective or delayed apoptosis, thus facilitating tumor growth or survival. We analyzed here, the basal expression of precursors of apoptotic Caspases in normal cervical epithelium, HPV+ cervical tumor samples and HPV+ tumor-derived cell lines.Expression of initiator and effector Caspases was analyzed by immunochemistry...
The goal of this study was to analyze the cellular distribution and possible alterations of β-catenin and E-cadherin proteins in different histologic types of uterine cervical cancer and precursor lesions, compared to normal controls.We performed an immunochemical staining analysis of the cellular distribution of β-catenin and E-cadherin proteins in biopsy samples from 20 normal exocervical squamous...
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