Search results for: Marco Vinceti

Items from 1 to 20 out of 45 results

article

Seroprevalence of anti-SARS-CoV-2 antibodies in the Northern Italy population before the COVID-19 second wave

Nausicaa Berselli, Tommaso Filippini, Stefania Paduano, Marcella Malavolti, more

International Journal of Occupational Medicine and Environmental Health > 2021 > 35 > 1 > 63-74

ObjectivesThe COVID-19 pandemic is due to SARS-CoV-2 coronavirus infections. It swept across the world in the spring of 2020, and so far it has caused a huge number of hospitalizations and deaths. In the present study, the authors investigated serum anti-SARS-CoV-2 antibody prevalence in the period of June 1–September 25, 2020, in 7561 subjects in Modena, Northern Italy.Material and MethodsThe study...

article

Dietary cadmium and risk of breast cancer subtypes defined by hormone receptor status: A prospective cohort study

Sara Grioni, Claudia Agnoli, Vittorio Krogh, Valeria Pala, more

International Journal of Cancer > 144 > 9 > 2153 - 2160

Diet is the primary source of cadmium—a proven Group 1 human carcinogen—for non‐smokers. Observational studies investigating the effect of cadmium from food sources on breast cancer risk have produced inconsistent results. We examined the association between dietary cadmium and risk of breast cancer defined by estrogen receptor (ER), progesterone receptor (PR) and HER2 status, in 8924 women recruited...

article

Environmental Selenium and Human Health: an Update

Marco Vinceti, Tommaso Filippini, Lauren A. Wise

Current Environmental Health Reports > 2018 > 5 > 4 > 464-485

Purpose of Review Selenium, a trace element, is ubiquitous in the environment. The main source of human exposure is diet. Despite its nutritional benefits, it is one of the most toxic naturally occurring elements. Selenium deficiency and overexposure have been associated with adverse health effects. Its level of toxicity may depend on its chemical form, as inorganic and organic species have distinct...

article

Cancer incidence following long-term consumption of drinking water with high inorganic selenium content

Marco Vinceti, Massimo Vicentini, Lauren A. Wise, Claudio Sacchettini, more

Science of The Total Environment > 2018 > 635 > C > 390-396

Selenium, a trace element to which humans are exposed mainly through diet, has been involved in the etiology of human cancer. We investigated the long-term effects of selenium exposure on cancer incidence using data from a natural experiment in Northern Italy. During the 1970s–1980s, in a part of the Italian municipality of Reggio Emilia, residents were inadvertently exposed to unusually high levels...

article

Selenium exposure and the risk of type 2 diabetes: a systematic review and meta-analysis

Marco Vinceti, Tommaso Filippini, Kenneth J. Rothman

European Journal of Epidemiology > 2018 > 33 > 9 > 789-810

In 2007, supplementation with the trace element selenium in a trial was unexpectedly found to be associated with an excess risk of type 2 diabetes. Given the concerns raised by these findings and the large number of recent studies on this topic, we reviewed the available literature with respect to this possible association. In this paper, we assessed the results of both experimental and nonexperimental...

article

Diet composition and serum levels of selenium species: A cross-sectional study

Tommaso Filippini, Bernhard Michalke, Lauren A. Wise, Carlotta Malagoli, more

Food and Chemical Toxicology > 2018 > 115 > C > 482-490

Selenium is a trace element of both nutritional and toxicological interest, depending on its dose and chemical form. Diet is the primary source of exposure for most individuals. We sought to investigate the influence of food intake on serum levels of selenium species.Among fifty subjects randomly selected from a Northern Italian population, we assessed dietary habits using a validated semi-quantitative...

article

Riluzole and other prognostic factors in ALS: a population-based registry study in Italy

Jessica Mandrioli, Sara Angela Malerba, Ettore Beghi, Nicola Fini, more

Journal of Neurology > 2018 > 265 > 4 > 817-827

Objective In this prospective population-based registry study on ALS survival, we investigated the role of riluzole treatment, together with other clinical factors, on the prognosis in incident ALS cases in Emilia Romagna Region (ERR), Italy. Methods A registry for ALS has been collecting all incident cases in ERR since 2009. Detailed clinical data from all patients diagnosed with ALS between 1...

article

A GIS-based atmospheric dispersion model for pollutants emitted by complex source areas

Sergio Teggi, Sofia Costanzini, Grazia Ghermandi, Carlotta Malagoli, more

Science of The Total Environment > 2018 > 610-611 > C > 175-190

Gaussian dispersion models are widely used to simulate the concentrations and deposition fluxes of pollutants emitted by source areas. Very often, the calculation time limits the number of sources and receptors and the geometry of the sources must be simple and without holes. This paper presents CAREA, a new GIS-based Gaussian model for complex source areas. CAREA was coded in the Python language,...

article

A selenium species in cerebrospinal fluid predicts conversion to Alzheimer’s dementia in persons with mild cognitive impairment

Marco Vinceti, Annalisa Chiari, Marcel Eichmüller, Kenneth J. Rothman, more

Alzheimer's Research & Therapy > 2017 > 9 > 1 > 1-11

Background Little is known about factors influencing progression from mild cognitive impairment to Alzheimer’s dementia. A potential role of environmental chemicals and specifically of selenium, a trace element of nutritional and toxicological relevance, has been suggested. Epidemiologic studies of selenium are lacking, however, with the exception of a recent randomized trial based on an organic selenium...

article

The role of cadmium in obesity and diabetes

Alexey A. Tinkov, Tommaso Filippini, Olga P. Ajsuvakova, Jan Aaseth, more

Science of The Total Environment > 2017 > 601-602 > C > 741-755

Multiple studies have shown an association between environmental exposure to hazardous chemicals including toxic metals and obesity, diabetes, and metabolic syndrome. At the same time, the existing data on the impact of cadmium exposure on obesity and diabetes are contradictory. Therefore, the aim of the present work was to review the impact of cadmium exposure and status on the risk and potential...

article

Lead, cadmium and mercury in cerebrospinal fluid and risk of amyotrophic lateral sclerosis: A case-control study

Marco Vinceti, Tommaso Filippini, Jessica Mandrioli, Federica Violi, more

Journal of Trace Elements in Medicine and Biology > 2017 > 43 > C > 121-125

Exposure to neurotoxic chemicals such as pesticides, selenium, and heavy metals have been suggested to play a role in the etiology of amyotrophic lateral sclerosis (ALS). We assessed exposure to lead, cadmium, and mercury in 38 ALS patients (16 men and 22 females) and 38 hospital-admitted controls by using their cerebrospinal fluid (CSF) content as biomarker. We determined CSF heavy metal levels with...

article

Pesticide exposure assessed through agricultural crop proximity and risk of amyotrophic lateral sclerosis

Marco Vinceti, Tommaso Filippini, Federica Violi, Kenneth J. Rothman, more

Environmental Health > 2017 > 16 > 1 > 1-14

Background Epidemiologic studies have raised the possibility that some pesticide compounds induce the neurodegenerative disease amyotrophic lateral sclerosis (ALS), though the available evidence is not entirely consistent. Methods We conducted a population-based case-control study in two Italian populations to assess the extent to which residence in the vicinity of agricultural crops associated...

article

Redox speciation of iron, manganese, and copper in cerebrospinal fluid by strong cation exchange chromatography – sector field inductively coupled plasma mass spectrometry

Nikolay Solovyev, Marco Vinceti, Peter Grill, Jessica Mandrioli, more

Analytica Chimica Acta > 2017 > 973 > C > 25-33

A new method of simultaneous redox speciation of iron (II/III), manganese (II/III), and copper (I/II) in cerebrospinal fluid (CSF) has been designed. For the separation of redox species strong cation exchange chromatography (SCX) with isocratic elution was employed. Species were detected using inductively coupled plasma sector field mass spectrometry (ICP-sf-MS), operating at medium resolution. The...

article

Pesticides, polychlorinated biphenyls and polycyclic aromatic hydrocarbons in cerebrospinal fluid of amyotrophic lateral sclerosis patients: a case-control study

Marco Vinceti, Federica Violi, Manolis Tzatzarakis, Jessica Mandrioli, more

Environmental Research > 2017 > 155 > C > 261-267

Neurotoxic chemicals including several pesticides have been suggested to play a role in the etiology of amyotrophic lateral sclerosis (ALS). We investigated the relation between organochlorine pesticides and their metabolites (OCPs), polychlorinated biphenyls (PCBs) and polycyclic aromatic hydrocarbons (PAHs) in the etiology of sporadic ALS, determining for the first time their levels in cerebrospinal...

article

The effect of potassium supplementation on blood pressure in hypertensive subjects: A systematic review and meta-analysis

Tommaso Filippini, Federica Violi, Roberto D'Amico, Marco Vinceti

International Journal of Cardiology > 2017 > 230 > C > 127-135

Several intervention studies have investigated the relation between potassium intake and blood-pressure, particularly in hypertensive subjects. However, uncertainties still exist about the existence and the amount of such an effect, and about the role of some potential effect-modifiers, including the baseline potassium intake and geographical area.We carried out a systematic review of the evidence...

article

Environmental metal contamination and health impact assessment in two industrial regions of Romania

Mirela Nedelescu, Daniela Baconi, Aurora Neagoe, Virgil Iordache, more

Science of The Total Environment > 2017 > 580 > C > 984-995

We investigated two Romanian industrial regions– Copşa Mică and Zlatna, to assess the current situation of soil pollution and bioaccumulation of Pb, Cd, Cu and Zn in different vegetable species and possible risks to consumers. Both total and mobile forms of the metals were determined in soil samples, and metal content in the edible parts of root vegetable samples was also assessed.The concentrations...

article

Validity of hospital discharge records to identify pregestational diabetes in an Italian population

Lucia Borsari, Carlotta Malagoli, Paola Ballotari, Gianfranco De Girolamo, more

Diabetes Research and Clinical Practice > 2017 > 123 > C > 106-111

In recent years, the prevalence of pregestational diabetes (PGDM) and the concern about the possibility of adverse pregnancy outcomes in affected women have been increasing. Routinely collected health data represent a timely and cost-efficient approach in PGDM epidemiological research. This study aims to evaluate the reliability of hospital discharge (HD) coding to identify a population-based cohort...

article

Passive exposure to agricultural pesticides and risk of childhood leukemia in an Italian community

Carlotta Malagoli, Sofia Costanzini, Julia E. Heck, Marcella Malavolti, more

International Journal of Hygiene and Environmental Health > 2016 > 219 > 8 > 742-748

Exposure to pesticides has been suggested as a risk factor for childhood leukemia, but definitive evidence on this relation and the specific pesticides involved is still not clear.We carried out a population-based case-control study in a Northern Italy community to assess the possible relation between passive exposure to agricultural pesticides and risk of acute childhood leukemia.We assessed passive...

article

Determinants of serum cadmium levels in a Northern Italy community: A cross-sectional study

Tommaso Filippini, Bernhard Michalke, Carlotta Malagoli, Peter Grill, more

Environmental Research > 2016 > 150 > C > 219-226

Cadmium (Cd) is a heavy metal and a serious environmental hazard to humans. Some uncertainties still exist about major sources of Cd exposure in non-occupationally exposed subjects in addition to cigarette smoking, such as diet and outdoor air pollution. We sought to determine the influence of these sources on a biomarker of exposure, serum Cd concentration.We recruited 51 randomly selected residents...

article

Long-term mortality patterns in a residential cohort exposed to inorganic selenium in drinking water

Marco Vinceti, Paola Ballotari, Craig Steinmaus, Carlotta Malagoli, more

Environmental Research > 2016 > 150 > C > 348-356

Selenium (Se) is a metalloid of considerable nutritional and toxicological importance in humans. To date, limited epidemiologic evidence exists about the health effects of exposure to this trace element in drinking water. We investigated the relationship between Se levels in water and mortality in the municipality of Reggio Emilia, Italy, where high levels of Se were previously observed in drinking...

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INFONA - science communication portal

Search results for: Marco Vinceti

Seroprevalence of anti-SARS-CoV-2 antibodies in the Northern Italy population before the COVID-19 second wave

Dietary cadmium and risk of breast cancer subtypes defined by hormone receptor status: A prospective cohort study

Environmental Selenium and Human Health: an Update

Cancer incidence following long-term consumption of drinking water with high inorganic selenium content

Selenium exposure and the risk of type 2 diabetes: a systematic review and meta-analysis

Diet composition and serum levels of selenium species: A cross-sectional study

Riluzole and other prognostic factors in ALS: a population-based registry study in Italy

A GIS-based atmospheric dispersion model for pollutants emitted by complex source areas

A selenium species in cerebrospinal fluid predicts conversion to Alzheimer’s dementia in persons with mild cognitive impairment

The role of cadmium in obesity and diabetes

Lead, cadmium and mercury in cerebrospinal fluid and risk of amyotrophic lateral sclerosis: A case-control study

Pesticide exposure assessed through agricultural crop proximity and risk of amyotrophic lateral sclerosis

Redox speciation of iron, manganese, and copper in cerebrospinal fluid by strong cation exchange chromatography – sector field inductively coupled plasma mass spectrometry

Pesticides, polychlorinated biphenyls and polycyclic aromatic hydrocarbons in cerebrospinal fluid of amyotrophic lateral sclerosis patients: a case-control study

The effect of potassium supplementation on blood pressure in hypertensive subjects: A systematic review and meta-analysis

Environmental metal contamination and health impact assessment in two industrial regions of Romania

Validity of hospital discharge records to identify pregestational diabetes in an Italian population

Passive exposure to agricultural pesticides and risk of childhood leukemia in an Italian community

Determinants of serum cadmium levels in a Northern Italy community: A cross-sectional study

Long-term mortality patterns in a residential cohort exposed to inorganic selenium in drinking water

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