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Inhibition of rat neuronal Na+/K+‐ATPase α3 isoform at low (100 nM) ouabain concentration led to activation of MAP kinase cascade via PKC and PIP3 kinase. In contrast to ouabain‐sensitive α3 isoform of Na+/K+‐ATPase, an ouabain‐resistant α1 isoform (inhibition with 1 mM of ouabain) of Na+/K+‐ATPase regulates MAP kinase via Src kinase dependent reactions. Using of Annexin V‐FITC apoptotic test to determine...