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Acne vulgaris is a chronic inflammatory skin disease. Antibiotics, particularly clindamycin and erythromycin, are used for the treatment of acne vulgaris. However, emerging antibiotic‐resistant strains have been an important problem. This study aims to evaluate the efficiency and safety of a novel water‐soluble herbal acne patch (WHAP) compared with the hydrocolloid acne patch (HAP) in mild to moderate...