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Objective
Weight regain occurs after medical weight loss via mechanisms of post‐weight‐loss “metabolic adaptation.” The relationship of inflammatory proteins with weight loss/regain was studied to determine a role for inflammation in metabolic adaptation.
Methods
Seventy‐four proteins central to inflammation and immune regulation (Olink) were analyzed in plasma from up to 490 participants in a...
Aim: To develop a novel metabolic computer model of the natural lifetime progression of type 2 diabetes that generates dynamic risk factor trajectories consistent with prespecified lifetime therapeutic strategies, in order to enhance the long-term economic and outcome modelling of type 2 diabetes and its complications. Methods: The main model drivers of progressive disease were changes in insulin...
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