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ObjectiveOpioids can suppress gonadal hormone production, which may result in low testosterone levels. To date, there have been no large‐scale population‐based studies examining the extent to which opioid use may contribute to changes in testosterone levels.
DesignCross‐sectional study.
Setting2011–2012 National Health and Nutrition Examination Survey.
SubjectsParticipants 17 years and older who...
Background A recent Canadian case–control study reported a 4.5-fold increased risk of retinal detachment (RD) during oral fluoroquinolone use. Of the fluoroquinolone-exposed cases, 83 % were exposed to ciprofloxacin. We sought to replicate this finding, and assess whether it applied to all fluoroquinolones. Methods In two large US healthcare databases, we performed three case–control analyses: one...
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