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Aims
To determine whether a net decline in glycosylated haemoglobin (HbA1c) from early to late pregnancy is associated with lower risk of adverse perinatal outcomes at delivery among women with pregestational diabetes.
Methods
A retrospective analysis from 2012 to 2016 at a tertiary care centre. The exposure was the net change in HbA1c from early (<20 weeks gestation) to late pregnancy (≥20 weeks...
Purpose of Review To review the current evidence of the safety and efficacy of the use of oral agents for treatment of gestational diabetes (GDM). Recent Findings The use of metformin and glyburide in pregnancy for treatment of GDM has dramatically increased since the early 2000s. Meta-analyses suggest that glyburide may increase the risk for large for gestational (LGA) infants and neonatal hypoglycemia...
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