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Cardiovascular disease, including atherosclerosis and critical limb ischemia, affects millions of people worldwide. There is a clinical need to base treatment decisions on quantitative analysis of the plaque composition. However, no reliable clinical methods to quantify the mechanical properties of plaque components and detect plaque vulnerability currently exist, particularly for coronary disease...
Volumetric 3D ultrasound captures a region of interest more completely than cross-sectional 2D imaging, but 3D implementation has been limited. Mechanical wobbler and matrix-array probes can do 3D imaging, but these probes tend to be bulky and/or expensive, and precise orientation of the image with respect to the patient is not measured. In this work, we present a method of acquiring volumetric 3D...
In this study, we investigated the feasibility of using 3.5-Fr circular phased array IVUS catheters for minimally invasive, image-guided hyperthermia treatment of tumors in the brain. Feasibility was demonstrated in two ways: 1) by fitting a 3.5-Fr IVUS catheter through burr holes, for 20 MHz imaging, and 2) by testing a modified circular array for therapy potential with 18.5-MHz and 9.0 MHz CW excitation...
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