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Reversible thiol‐disulfide exchange chemistry is of particular interest in drug delivery systems. However, high levels of glutathione (GSH) in cancer cells are hard to distinguish from GSH in normal cells, resulting in unmanageable cytotoxic drug release. This study investigates the spatiotemporally‐controlled irreversible degradation of Ir‐based photosensitizer (TIr3)‐encapsulating nanogels (IrNG)...
Reversible thiol‐disulfide exchange chemistry is of particular interest in drug delivery systems. However, high levels of glutathione (GSH) in cancer cells are hard to distinguish from GSH in normal cells, resulting in unmanageable cytotoxic drug release. This study investigates the spatiotemporally‐controlled irreversible degradation of Ir‐based photosensitizer (TIr3)‐encapsulating nanogels (IrNG)...
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