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The homomeric GABA‐ρ ligand‐gated ion channels (also known as GABAC or GABAA‐ρ receptors) are similar to heteromeric GABAA receptors in structure, function and mechanism of action. However, their distinctive pharmacological properties and distribution make them of special interest. This review focuses on GABA‐ρ ion channel structure, ligand selectivity toward ρ receptors over heteromeric GABAA receptor...