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Background
The association of sex hormones with C‐reactive protein (CRP) levels has been reported. However, this association remains unexplored in children in whom important anthropometric and hormonal changes are taking place.
Objectives
To analyze the association between high‐sensitivity CRP (hs‐CRP) and testosterone, estradiol and sex hormone‐binding globulin (SHBG) levels in a population‐based...
Objective
The aim of this study was to evaluate the association between obesity and plasma adropin levels in two cohorts of children at two different ages.
Methods
Adropin concentrations were measured in 71 prepubertal and 41 pubertal children with obesity and their age‐ and sex‐matched normal weight counterparts (69 prepubertal and 42 pubertal children). Information was available in these children...
Background
Nesfatin‐1, an anorexigenic peptide, has been associated with food intake and thermogenesis, with discordant findings in humans and scarce studies in children to date.
Objectives
The aim of this study was to analyze the relationship of obesity with nesfatin‐1 levels in two cohorts of children.
Methods
Plasma nesfatin‐1 concentrations were analyzed in 6‐ to 9‐year‐olds (n = 140) and...
In the present work we report the development and validation of a fast liquid chromatography–mass spectrometry method for the simultaneous determination of endogenous nucleosides derived from DNA and RNA in urine. The target compounds were 2′-deoxyguanosine and 8-hydroxy-2′-deoxyguanosine, derived from DNA, and the analogue 8-hydroxyguanosine, derived from RNA, together with adenosine, 1-methyladenosine,...
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