Search results for: Luca Bergamaschi

Items from 1 to 20 out of 63 results

article

Noninvasive Assessment in Takotsubo Syndrome: A Diagnostic Challenge

Sara Amicone, Andrea Impellizzeri, Francesco Pio Tattilo, Khrystyna Ryabenko, more

Takotsubo syndrome (TTS) is a clinical syndrome characterized by a transient left ventricular dysfunction whose diagnosis can be challenging due to its resemblance to acute myocardial infarction (AMI). Despite the growing recognition of TTS, acute complications and long‐term mortality rates are comparable to those observed in AMI patients. In this context, a systematic diagnostic approach is imperative...

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Clinical impact of multimodality assessment of myocardial viability

Lisa Canton, Nicole Suma, Sara Amicone, Andrea Impellizzeri, more

Echocardiography > 41 > 7 > n/a - n/a

Coronary artery disease (CAD) is a prevalent cause of left ventricular dysfunction. Nevertheless, effective elective revascularization, particularly surgical revascularization, can enhance long‐term outcomes and, in selected cases, global left ventricular contractility. The assessment of myocardial viability and scars is still relevant in guiding treatment decisions and selecting patients who are...

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Caring for children with cancer evacuated from Ukraine: The patients’ perception

Marcello Bolognese, Maura Massimino, Daniele Cabibbe, Marco Zecca, more

Pediatric Blood & Cancer > 71 > 8 > n/a - n/a

Background and aims Since the beginning of the war in Ukraine on February 24, 2022, many pediatric oncology centers welcomed evacuated patients. To better understanding the needs of patients and families arriving at two Lombardy hospitals in the period March to November 2022, an anonymous questionnaire investigated the families’ backgrounds, feelings, and impressions about hospitality and care. ...

article

Treatment at relapse for synovial sarcoma of children and adolescents: A multi‐institutional European retrospective analysis

Andrea Ferrari, Daniel Orbach, Luca Bergamaschi, Reineke A. Schoot, more

Pediatric Blood & Cancer > 71 > 7 > n/a - n/a

Purpose Though the prognosis for pediatric patients with localised synovial sarcoma (SS) is generally good, the chances of being cured after relapse are limited. This study describes a retrospective multi‐institutional series of relapsing SS patients treated at six selected European referral centers for pediatric sarcoma. Patients and methods The study included 41 patients <21 years with relapsing...

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Targeting subclinical ventricular dysfunction in atrial fibrillation: What can myocardial work add?

Elisa Gherbesi, Luca Bergamaschi, Carmine Pizzi, Stefano Carugo

Echocardiography > 41 > 5 > n/a - n/a

Atrial fibrillation (AF) could impact on left ventricular function leading to a sublinical myocardial dysfunction, as identified by myocardial work parameters in a population‐based cohort of AF patients compared with healthy individuals; factors associated with these parameters are also shown. SBP: systolic blood pressure; LAVI: left atrial volume index

article

Local treatment in initially unresected non‐rhabdomyosarcoma soft‐tissue sarcomas of children and adolescents: A retrospective single‐center experience

Andrea Ferrari, Sabina Vennarini, Marco Fiore, Luca Bergamaschi, more

Pediatric Blood & Cancer > 71 > 4 > n/a - n/a

Background Pediatric non‐rhabdomyosarcoma soft‐tissue sarcomas (NRSTS) are a heterogeneous group of aggressive tumors. Patients with locally advanced/initially unresected disease represent a subset of patients with unsatisfactory outcome: limited data are available on the best treatment approach, in particular regarding local therapy. Methods This retrospective analysis concerned 71 patients < 21...

article

Myocardial strain of the left ventricle by speckle tracking echocardiography: From physics to clinical practice

Elisa Gherbesi, Silvia Gianstefani, Francesco Angeli, Khrystyna Ryabenko, more

Echocardiography > 41 > 1 > n/a - n/a

Speckle tracking echocardiography (STE) is a reliable imaging technique of recognized clinical value in several settings. This method uses the motion of ultrasound backscatter speckles within echocardiographic images to derive myocardial velocities and deformation parameters, providing crucial insights on several cardiac pathological and physiological processes. Its feasibility, reproducibility, and...

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Relapse after non‐metastatic rhabdomyosarcoma: The impact of routine surveillance imaging on early detection and post‐relapse survival

Michela Casanova, Luca Bergamaschi, Stefano Chiaravalli, Carlo Morosi, more

Pediatric Blood & Cancer > 70 > 2 > n/a - n/a

Background Patients with rhabdomyosarcoma (RMS) whose disease relapses have little chance of being cured, so front‐line treatments are usually followed up with surveillance imaging in an effort to detect any recurrences as early as possible, and thereby improve post‐relapse outcomes. The real benefit of such routine surveillance imaging in RMS remains to be demonstrated, however. This retrospective,...

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Relapse after nonmetastatic rhabdomyosarcoma: Salvage rates and prognostic variables

Luca Bergamaschi, Stefano Chiaravalli, Virginia Livellara, Giovanna Sironi, more

Pediatric Blood & Cancer > 70 > 1 > n/a - n/a

Background Patients with relapsing rhabdomyosarcoma (RMS) pose a therapeutic challenge, and the survival rate is reportedly poor. We describe a retrospective series of relapsing RMS patients treated at a referral center for pediatric sarcoma, investigating the pattern of relapse, salvage rates, and factors correlating with final outcomes. Methods The analysis concerned 105 patients <21 years...

article

Metastatic rhabdomyosarcoma: Evidence of the impact of radiotherapy on survival. A retrospective single‐center experience

Andrea Ferrari, Luca Bergamaschi, Stefano Chiaravalli, Virginia Livellara, more

Pediatric Blood & Cancer > 69 > 11 > n/a - n/a

Background The prognosis for patients with metastatic rhabdomyosarcoma (RMS) remains largely unsatisfactory despite the adoption of intensive multimodal therapy. To assess the role of different treatments adopted over the years, we retrospectively analyzed a cohort of patients <21 years old with metastatic RMS, treated from 1990 to 2020 at a referral center for pediatric sarcomas. Methods Patients...

article

The usefulness of speckle tracking echocardiography in identifying subclinical myocardial dysfunction in young adults recovered from mild COVID‐19

Elisa Gherbesi, Luca Bergamaschi, Ignazio Cusmano, Thien Trung Tien, more

Echocardiography > 39 > 9 > 1190 - 1197

Background Myocardial strain assessed with speckle tracking echocardiography is a sensitive marker of cardiac dysfunction. Both left‐ventricular global longitudinal strain (LV‐GLS) and right ventricular longitudinal strain (RV‐LS) were affected by severe SARS‐CoV‐2 infection. However, data about cardiac involvement in patients with asymptomatic/mild Coronavirus disease‐19 (COVID‐19) is still lacking...

article

Extraosseous Ewing sarcoma in children and adolescents: A retrospective series from a referral pediatric oncology center

Virginia Livellara, Luca Bergamaschi, Nadia Puma, Stefano Chiaravalli, more

Pediatric Blood & Cancer > 69 > 5 > n/a - n/a

Background Extraosseous Ewing sarcoma is a rare entity and less is known about its clinical behavior and optimal treatment than for its counterpart in bone. This study is a retrospective analysis on a cohort of patients <21 years treated according to a “soft tissue sarcoma approach.” Methods The “extraosseous” origin of the tumor was established on radiological findings, based on the lack of...

article

SARS‐CoV‐2 vaccination for adolescents and young adult patients treated at a specialist pediatric oncology unit

Olga Nigro, Giovanna Sironi, Luca Bergamaschi, Giovanna Gattuso, more

Pediatric Blood & Cancer > 68 > 10 > n/a - n/a

This brief report describes the SARS‐CoV‐2 vaccination program at our pediatric oncology unit. Adopting Italian regulations, patients treated for cancer within the previous 6 months were offered vaccination with the Pfizer‐BioNtech vaccine if aged ≥16 years, and with the Pfizer‐BioNtech or Moderna vaccine if aged ≥18 years. From March 24 to April 28, 2021, 80/89 adolescent and young adult patients...

article

A new preconditioning approach for an interior point‐proximal method of multipliers for linear and convex quadratic programming

Luca Bergamaschi, Jacek Gondzio, Ángeles Martínez, John W. Pearson, more

Numerical Linear Algebra with Applications > 28 > 4 > n/a - n/a

In this article, we address the efficient numerical solution of linear and quadratic programming problems, often of large scale. With this aim, we devise an infeasible interior point method, blended with the proximal method of multipliers, which in turn results in a primal‐dual regularized interior point method. Application of this method gives rise to a sequence of increasingly ill‐conditioned linear...

article

Cutaneous melanoma in children and adolescents: The EXPeRT/PARTNER diagnostic and therapeutic recommendations

Andrea Ferrari, Ricardo Lopez Almaraz, Yves Reguerre, Maja Cesen, more

Pediatric Blood & Cancer > 68 > S4 > n/a - n/a

Cutaneous melanoma is rare in children and, like other very rare pediatric tumors, it suffers from a shortage of knowledge and clinical expertise. The clinical management of pediatric melanoma is often challenging. Its clinical and pathological diagnosis may be difficult, and there is no standard treatment. In the absence of specific treatment guidelines, young patients are generally treated following...

article

Response of the Authors

Luca Bergamaschi, Pasquale Paolisso, Francesco Angeli, Michele Fabrizio, more

Annals of Noninvasive Electrocardiology > 26 > 3 > n/a - n/a

article

The value of ECG changes in risk stratification of COVID‐19 patients

Luca Bergamaschi, Emanuela Concetta D’Angelo, Pasquale Paolisso, Sebastiano Toniolo, more

Annals of Noninvasive Electrocardiology > 26 > 3 > n/a - n/a

Background There is growing evidence of cardiac injury in COVID‐19. Our purpose was to assess the prognostic value of serial electrocardiograms in COVID‐19 patients. Methods We evaluated 269 consecutive patients admitted to our center with confirmed SARS‐CoV‐2 infection. ECGs available at admission and after 1 week from hospitalization were assessed. We evaluated the correlation between ECGs findings...

article

Complexity index in sarcoma and genomic grade index gene signatures in rhabdomyosarcoma of pediatric and adult ages

Andrea Ferrari, Maria Federica Iannó, Andrea Carenzo, Orazio Fortunato, more

Pediatric Blood & Cancer > 68 > 7 > n/a - n/a

Background Rhabdomyosarcoma (RMS), the most frequent soft‐tissue sarcoma in childhood, shows extensive heterogeneity in histology, site and age of onset, clinical course, and prognosis. Adolescents and young adults (AYA) with RMS form a subgroup of patients whose survival lacks behind that of children while diagnosed with histologically similar tumors. Procedures A 67‐gene prognostic signature...

article

Medulloblastoma and familial adenomatous polyposis: Good prognosis and good quality of life in the long‐term?

Maura Massimino, Stefano Signoroni, Luna Boschetti, Luisa Chiapparini, more

Pediatric Blood & Cancer > 68 > 4 > n/a - n/a

Introduction Mutations of the APC (adenomatous polyposis coli) gene correlate mainly with familial adenomatous polyposis (FAP), but can occasionally be pathogenic for medulloblastoma (MBL) wingless‐related integration site (WNT) subtype, the course of which has only recently been described. Methods We retrieved all patients with documented germline APC mutations and a diagnosis of MBL to examine...

article

Where are adolescents with cutaneous melanoma treated? An Italian nationwide study on referrals based on hospital discharge records

Andrea Ferrari, Alice Bernasconi, Giovanna Sironi, Laura Botta, more

Pediatric Blood & Cancer > 68 > 1 > n/a - n/a

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INFONA - science communication portal

Search results for: Luca Bergamaschi

Noninvasive Assessment in Takotsubo Syndrome: A Diagnostic Challenge

Clinical impact of multimodality assessment of myocardial viability

Caring for children with cancer evacuated from Ukraine: The patients’ perception

Treatment at relapse for synovial sarcoma of children and adolescents: A multi‐institutional European retrospective analysis

Targeting subclinical ventricular dysfunction in atrial fibrillation: What can myocardial work add?

Local treatment in initially unresected non‐rhabdomyosarcoma soft‐tissue sarcomas of children and adolescents: A retrospective single‐center experience

Myocardial strain of the left ventricle by speckle tracking echocardiography: From physics to clinical practice

Relapse after non‐metastatic rhabdomyosarcoma: The impact of routine surveillance imaging on early detection and post‐relapse survival

Relapse after nonmetastatic rhabdomyosarcoma: Salvage rates and prognostic variables

Metastatic rhabdomyosarcoma: Evidence of the impact of radiotherapy on survival. A retrospective single‐center experience

The usefulness of speckle tracking echocardiography in identifying subclinical myocardial dysfunction in young adults recovered from mild COVID‐19

Extraosseous Ewing sarcoma in children and adolescents: A retrospective series from a referral pediatric oncology center

SARS‐CoV‐2 vaccination for adolescents and young adult patients treated at a specialist pediatric oncology unit

A new preconditioning approach for an interior point‐proximal method of multipliers for linear and convex quadratic programming

Cutaneous melanoma in children and adolescents: The EXPeRT/PARTNER diagnostic and therapeutic recommendations

Response of the Authors

The value of ECG changes in risk stratification of COVID‐19 patients

Complexity index in sarcoma and genomic grade index gene signatures in rhabdomyosarcoma of pediatric and adult ages

Medulloblastoma and familial adenomatous polyposis: Good prognosis and good quality of life in the long‐term?

Where are adolescents with cutaneous melanoma treated? An Italian nationwide study on referrals based on hospital discharge records

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