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Alamandine is a heptapeptide from the renin‐angiotensin system (RAS) with similar structure/function to angiotensin‐(1‐7) [ang‐(1‐7)], but they act via different receptors. It remains elusive whether alamandine is an antiproliferative agent like ang‐(1‐7). The goal of this study was to evaluate the potential antiproliferative activity of alamandine and the underlying cellular signaling. We evaluated...
Breast cancer is the most prevalent cancer in women worldwide. Its molecular subtypes are based on the presence/absence of estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER2). MACL‐1 and MGSO‐3 are cell lines derived from primary tumor sites of patients diagnosed with luminal A subtype carcinoma (ER+/PR+/HER2−) and ductal carcinoma in situ (ER−/PR−/HER2+),...
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