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Growing evidence gathered from transgenic animal models of Alzheimer’s disease (AD) indicates that the intraneuronal accumulation of amyloid-β (Aβ) peptides is an early event in the AD pathogenesis, producing cognitive deficits before the deposition of insoluble plaques. Levels of soluble Aβ are also a strong indicator of synaptic deficits and concurrent AD neuropathologies in post-mortem AD brain;...
Neuroscientists across Europe have been busy finding or consolidating partnerships, and sharpening their e-pencils, as they prepare for the next tranche of research and technology development (RTD) funding to be coordinated by the European Union. Entitled the Sixth Framework Programme, this ? 16 billion programme is the most ambitious that the European Commission has ever mounted. It covers a broad...
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