Search results for: Urvi Desai

Items from 1 to 20 out of 22 results

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‘Didn't See the Need’: Misperceptions about glucagon from the perspectives of people with diabetes and their caregivers

Heather L. Stuckey, Urvi Desai, Beth D. Mitchell, Teresa L. Pearson

Aims Severe hypoglycaemia among people with diabetes who use insulin can be a life‐threatening complication if left untreated. Although glucagon has been approved for treatment of hypoglycaemia since the 1960s, it has been underutilized. We aimed to understand the perceptions of people with diabetes and their caregivers about glucagon. Methods We conducted in‐depth, one‐on‐one telephone interviews...

article

Randomized phase 2 study of ACE‐083, a muscle‐promoting agent, in facioscapulohumeral muscular dystrophy

Jeffrey M. Statland, Craig Campbell, Urvi Desai, Chafic Karam, more

Muscle & Nerve > 66 > 1 > 50 - 62

Introduction/Aims Facioscapulohumeral muscular dystrophy (FSHD) is a slowly progressive muscular dystrophy without approved therapies. In this study we evaluated whether locally acting ACE‐083 could safely increase muscle volume and improve functional outcomes in adults with FSHD. Methods Participants were at least 18 years old and had FSHD1/FSHD2. Part 1 was open label, ascending dose, assessing...

article

The experience of a severe hypoglycaemic event from the perspective of people with diabetes and their caregivers: “What am I going to do?”

Heather L. Stuckey, Urvi Desai, Sarah B. King, Lyuba Popadic, more

Diabetic Medicine > 39 > 4 > n/a - n/a

Aims Among people with diabetes using insulin, severe hypoglycaemia (SH) can be a life‐threatening complication, if untreated. The personal experiences during an SH event from the perspectives of people with diabetes and their caregivers are not well‐characterized. This study assessed the perceptions of the event and the decision making processes of people with diabetes (T1D n = 36; T2D n = 24) and...

article

Reply: The Optimal Management of Electrodiagnostic Studies during COVID‐19 Outbreak

Charles D. Kassardjian, Urvi Desai, Pushpa Narayanaswami, the Quality and Patient Safety Committee of the AANEM

Muscle & Nerve > 62 > 3 > E54 - E54

article

Guidance for resumption of routine electrodiagnostic testing during the COVID‐19 pandemic

Urvi Desai, Charles D. Kassardjian, David Del Toro, Nida Gleveckas‐Martens, more

Muscle & Nerve > 62 > 2 > 176 - 181

As the world accommodates to the coronavirus disease 2019 (COVID‐19) pandemic, routine in‐person medical services are resuming. The resumption of non urgent electrodiagnostic (EDX) testing faces unique challenges due to the long duration of the procedure and direct close contact with patients, including studies with risk of exposure to oropharyngeal secretions. We provide consensus guidance for resumption...

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Practical guidance for managing electromyography requests and testing during the COVID‐19 pandemic

Charles D. Kassardjian, Urvi Desai, Pushpa Narayanaswami, the AANEM Quality and Patient Safety Committee of the AANEM

Muscle & Nerve > 62 > 1 > 30 - 33

The COVID‐19 pandemic has necessitated cancelation of elective or nonurgent contact with the healthcare system, including nonurgent nerve conduction studies and electromyography (electrodiagnostic [EDX] studies). The definitions of elective and nonurgent are physician judgments, and often are not straightforward. Clinical care must be provided to help our patients in a timely manner, while keeping...

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Temporal and Geographic Variation in the Incidence of Alzheimer's Disease Diagnosis in the US between 2007 and 2014

Noam Y. Kirson, Eric S. Meadows, Urvi Desai, Brian P. Smith, more

Journal of the American Geriatrics Society > 68 > 2 > 346 - 353

OBJECTIVES Our aim was to describe the incidence of Alzheimer's disease (AD) in the United States, overall and by geographic region. DESIGN We conducted retrospective analyses of administrative claims data for a 5% random sample of US Medicare beneficiaries aged 65 years or older. AD incidence, defined as a diagnosis for AD (International Classification of Disease, Ninth Revision, Clinical Modification...

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One‐Year Effect of the Medicare Annual Wellness Visit on Detection of Cognitive Impairment: A Cohort Study

Nicole R. Fowler, Noll L. Campbell, Gerhardt M. Pohl, Leanne M. Munsie, more

Journal of the American Geriatrics Society > 66 > 5 > 969 - 975

Objectives To examine the effect of the Medicare Annual Wellness Visit (AWV) on the detection of cognitive impairment and on follow‐up cognitive care for older adults. Design Retrospective matched‐cohort study. Setting United States. Participants A 5% random sample of fee‐for‐service Medicare beneficiaries continuously enrolled for 12 months before and after an index ambulatory visit occurring...

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Characteristics, Treatment Patterns, and Economic Outcomes of Patients Initiating Injectable Medications for Management of Type 2 Diabetes Mellitus in Japan: Results from a Retrospective Claims Database Analysis

Shuichi Suzuki, Urvi Desai, Alena Strizek, Jasmina Ivanova, more

Diabetes Therapy > 2018 > 9 > 3 > 1125-1141

Introduction This study’s objective was to describe characteristics, treatment patterns, and economic outcomes of type 2 diabetes mellitus (T2DM) patients initiating injectable antidiabetic medications in Japan. Methods Adults (≥ 18 years) with T2DM, ≥ 2 claims for injectable antidiabetics between 1 August 2011 and 31 July 2015 (first claim = index date), no evidence of type 1 diabetes mellitus,...

article

TRENDS IN HEALTH SERVICE USE AND POTENTIALLY AVOIDABLE HOSPITALIZATIONS PRIOR TO ALZHEIMER’S DISEASE DIAGNOSIS: A MATCHED, RETROSPECTIVE STUDY OF U.S. MEDICARE BENEFICIARIES

Urvi Desai, Noam Y. Kirson, Nori Mehta, Jody Wen, more

Alzheimer's & Dementia > 2017 > 13 > 7(S) > P1457-P1458

article

IS THE ANNUAL WELLNESS VISIT ADEQUATE TO IMPACT COGNITIVE CARE?

Nicole R. Fowler, Noll L. Campbell, Gerhardt M. Pohl, Leanne M. Munsie, more

Alzheimer's & Dementia > 2017 > 13 > 7(S) > P1158-P1159

article

Basal Insulin Persistence, Associated Factors, and Outcomes After Treatment Initiation: A Retrospective Database Study Among People with Type 2 Diabetes Mellitus in Japan

Irene Hadjiyianni, Urvi Desai, Shuichi Suzuki, Jasmina I. Ivanova, more

Diabetes Therapy > 2017 > 8 > 1 > 149-166

Introduction The objective of this study was to assess basal insulin persistence, associated factors, and economic outcomes for insulin-naïve people with type 2 diabetes mellitus (T2DM) in Japan. Methods People aged at least 18 years with T2DM with first claim for basal insulin between May 2006 and April 2013 (index date), no insulin use before index date, and continuous insurance coverage for 6 months...

article

Assessing the economic burden of Alzheimer’s disease patients first diagnosed by specialists

Noam Y. Kirson, Urvi Desai, Ljubica Ristovska, Alice Kate G. Cummings, more

BMC Geriatrics > 2016 > 16 > 1 > 1-8

Background It is not known if there is a differential impact on Alzheimer’s disease (AD) diagnosis and outcomes if/when patients are diagnosed with cognitive decline by specialists versus non-specialists. This study examined the cost trajectories of Medicare beneficiaries initially diagnosed by specialists compared to similar patients who received their diagnosis in primary care settings. Methods...

article

Acute and chronic systemic corticosteroid–related complications in patients with severe asthma

Patrick Lefebvre, Mei Sheng Duh, Marie-Hélène Lafeuille, Laurence Gozalo, more

Journal of Allergy and Clinical Immunology > 2015 > 136 > 6 > 1488-1495

Many patients with severe asthma require maintenance treatment with systemic corticosteroids (SCSs) to control daily symptoms and prevent serious acute exacerbations, but chronic SCS use is associated with complications.We sought to evaluate the risk of SCS-related complications by SCS exposure and quantify the associated health care costs and resource use in patients with severe asthma.We performed...

article

Design, synthesis, and in vivo activity of novel inhibitors of delta-5 desaturase for the treatment of metabolic syndrome

Simon D.P. Baugh, Praveen K. Pabba, Joseph Barbosa, Eric Coulter, more

Bioorganic & Medicinal Chemistry Letters > 2015 > 25 > 18 > 3836-3839

The synthesis, SAR, and in vivo activity of inhibitors of delta-5 desaturase are described. Ring-constraint of the initial series provided access to a variety of in vitro active chemotypes, from which the indazole was selected. Examples from the indazole series displayed in vivo activity in reducing the enzymatic activity of liver delta-5 desaturase.

article

Medical costs of Alzheimer's disease misdiagnosis among US Medicare beneficiaries

Craig A. Hunter, Noam Y. Kirson, Urvi Desai, Alice Kate G. Cummings, more

Alzheimer's & Dementia > 2015 > 11 > 8 > 887-895

Recent developments in diagnostic technology can support earlier, more accurate diagnosis of non-Alzheimer's disease (AD) dementias.To evaluate potential economic benefits of early rule-out of AD, annual medical resource use and costs for Medicare beneficiaries potentially misdiagnosed with AD prior to their diagnosis of vascular dementia (VD) or Parkinson's disease (PD) were compared with that of...

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Functional limitations and healthcare resource utilization for individuals with cognitive impairment without dementia: Findings from a u.s. population-based survey

Jeffrey Scott Andrews, Noam Y. Kirson, Urvi Desai, Caroline J. Enloe, more

Alzheimer's & Dementia: The Journal of the Alzheimer's Association > 2015 > 11 > 7 Supplement > P664-P665

article

ASSESSING THE ECONOMIC BURDEN OF ALZHEIMER'S DISEASE PATIENTS TREATED BY SPECIALISTS WITHIN THREE MONTHS OF PRELIMINARY DIAGNOSIS OF COGNITIVE DECLINE

Craig A. Hunter, Noam Y. Kirson, Urvi Desai, Ljubica Ristovska, more

Alzheimer's & Dementia: The Journal of the Alzheimer's Association > 2014 > 10 > 4 Supplement > P277-P278

article

EXCESS COSTS ASSOCIATED WITH POSSIBLE MISDIAGNOSIS OF ALZHEIMER'S DISEASE AMONG PATIENTS WITH VASCULAR DEMENTIA IN A UK CPRD POPULATION

Michael Happich, Noam Y. Kirson, Urvi Desai, Sarah King, more

Alzheimer's & Dementia: The Journal of the Alzheimer's Association > 2014 > 10 > 4 Supplement > P911-P912

article

Excess costs associated with misdiagnosis of Alzheimer's disease among U.S. Medicare beneficiaries with vascular dementia or Parkinson's disease

Noam Kirson, Craig Hunter, Urvi Desai, Alice Cummings, more

Alzheimer's & Dementia > 2013 > 9 > 4(S) > P845-P846

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INFONA - science communication portal

Search results for: Urvi Desai

‘Didn't See the Need’: Misperceptions about glucagon from the perspectives of people with diabetes and their caregivers

Randomized phase 2 study of ACE‐083, a muscle‐promoting agent, in facioscapulohumeral muscular dystrophy

The experience of a severe hypoglycaemic event from the perspective of people with diabetes and their caregivers: “What am I going to do?”

Reply: The Optimal Management of Electrodiagnostic Studies during COVID‐19 Outbreak

Guidance for resumption of routine electrodiagnostic testing during the COVID‐19 pandemic

Practical guidance for managing electromyography requests and testing during the COVID‐19 pandemic

Temporal and Geographic Variation in the Incidence of Alzheimer's Disease Diagnosis in the US between 2007 and 2014

One‐Year Effect of the Medicare Annual Wellness Visit on Detection of Cognitive Impairment: A Cohort Study

Characteristics, Treatment Patterns, and Economic Outcomes of Patients Initiating Injectable Medications for Management of Type 2 Diabetes Mellitus in Japan: Results from a Retrospective Claims Database Analysis

TRENDS IN HEALTH SERVICE USE AND POTENTIALLY AVOIDABLE HOSPITALIZATIONS PRIOR TO ALZHEIMER’S DISEASE DIAGNOSIS: A MATCHED, RETROSPECTIVE STUDY OF U.S. MEDICARE BENEFICIARIES

IS THE ANNUAL WELLNESS VISIT ADEQUATE TO IMPACT COGNITIVE CARE?

Basal Insulin Persistence, Associated Factors, and Outcomes After Treatment Initiation: A Retrospective Database Study Among People with Type 2 Diabetes Mellitus in Japan

Assessing the economic burden of Alzheimer’s disease patients first diagnosed by specialists

Acute and chronic systemic corticosteroid–related complications in patients with severe asthma

Design, synthesis, and in vivo activity of novel inhibitors of delta-5 desaturase for the treatment of metabolic syndrome

Medical costs of Alzheimer's disease misdiagnosis among US Medicare beneficiaries

Functional limitations and healthcare resource utilization for individuals with cognitive impairment without dementia: Findings from a u.s. population-based survey

ASSESSING THE ECONOMIC BURDEN OF ALZHEIMER'S DISEASE PATIENTS TREATED BY SPECIALISTS WITHIN THREE MONTHS OF PRELIMINARY DIAGNOSIS OF COGNITIVE DECLINE

EXCESS COSTS ASSOCIATED WITH POSSIBLE MISDIAGNOSIS OF ALZHEIMER'S DISEASE AMONG PATIENTS WITH VASCULAR DEMENTIA IN A UK CPRD POPULATION

Excess costs associated with misdiagnosis of Alzheimer's disease among U.S. Medicare beneficiaries with vascular dementia or Parkinson's disease

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