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Single Track Location Shear Wave Elasticity Imaging (STL-SWEI) creates high resolution shear wave speed maps by comparing the tissue motion at each tracking location between spatially-offset radiation force excitations. While STL-SWEI circumvents the resolution-limiting effects of speckle noise, it requires a series of excitation-tracking ensembles to build up a lateral field of view, increasing the...
Myocardial elastance, derived from pressure-volume (PV) loops in the left ventricle (LV), can be used to assess LV function and myocardial performance. This method requires an invasive intracardiac pressure-volume catheter to be inserted in the LV, limiting the method's utility in clinical screening and monitoring. Strain echocardiography and cardiac acoustic radiation force impulse (ARFI) imaging...
Fetal short-lag spatial coherence (SLSC) imaging has demonstrated 64–85% increases in CNR and 17–29% increases in contrast relative to conventional B-mode imaging. However, despite its proven technical efficacy, the viability of fetal SLSC in the clinical setting remains unknown. The aims of this study were: 1) To demonstrate the feasibility of real-time SLSC imaging on existing hardware and 2) to...
Comb-Push Ultrasound Shear Elastography (CUSE) uses ultrasound beams focused simultaneously at multiple laterally-offset positions to induce shear waves in tissue, and uses the local propagation of the waves to estimate tissue elasticity everywhere in the extended field of view. Single Track Location Shear Wave Elasticity Imaging (STL-SWEI) uses sequentially excited and tracked shear waves from closely-spaced...
Myocardial elasticity is an important indicator of cardiac function and is affected in many disorders associated with heart failure. Ultrasound based interrogation of cardiac stiffness has been extensively studied in ex-vivo, open chest and intracardiac imaging environments. The ability to make these measurements robustly through non-invasive means such as transthoracic imaging would make them more...
Ultrasound imaging of deep abdominal targets suffers from low lateral resolution due to limited aperture size and low-frequency transmit pulses. We demonstrate phantom and in vivo imaging results using a device that allows a tracked mechanical sweep of a commercially available ultrasound array. The position data and device calibration have sufficient precision to allow coherent combination of the...
Four pigs, three with focal infarctions in the apical intraventricular septum (IVS) and/or left ventricular free wall (LVFW), were imaged with an intracardiac echocardiography (ICE) transducer. Custom beam sequences were used to excite the myocardium with focused acoustic radiation force (ARF) impulses and image the subsequent tissue response. Tissue displacement in response to the ARF excitation...
Four pigs, three with focal infarctions in the apical intraventricular septum (IVS) and/or left ventricular free wall (LVFW), were imaged with an intracardiac echocardiography (ICE) transducer. Custom beam sequences were used to excite the myocardium with focused acoustic radiation force (ARF) impulses and image the subsequent tissue response. Tissue velocity in response to the ARF excitation was...
An approach for myocardial elastography is presented for infarct visualization. Infarcts are visualized using passive strain in the ventricles induced by atrial contraction. Results are compared against ARFI and delay-enhanced contrast MR.
Acoustic Radiation Force Impulse (ARFI) methods have been validated for measuring tissue elastic properties, with shear wave velocimetry emerging as a quantitative way to measure stiffness. Using ultrasound to interrogate cardiac elasticity holds promise for diagnosis of cardiac dysfunction, but acquiring measurements has previously been an invasive procedure and not clinically viable. This work describes...
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