Wyniki wyszukiwania dla: Elizabeth Roughead

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artykuł

Impact of COVID‐19 restrictions on pathology service utilisation

Marianne H. Gillam, Elizabeth Roughead, Rosanna Tavella, Tom Dodd, więcej

Internal Medicine Journal > 52 > 1 > 42 - 48

Background Isolation and social distancing restrictions due to COVID‐19 have the potential to impact access to healthcare services. Aims To assess the use of pathology services during the COVID‐19 pandemic initial restrictions. Methods Repeated cross‐sectional study of pathology tests utilisation during a baseline time period early in 2020 compared with pre‐lockdown and lockdown due to COVID‐19...

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Risk of falls and injuries requiring hospitalisation after first‐eye cataract surgery in elderly Australians

Svetla Gadzhanova, Marianne Gillam, Elizabeth Roughead

Acta Ophthalmologica > 98 > 4 > e495 - e498

Purpose To investigate the impact of the type of the intraocular lenses (IOLs) in first‐eye cataract surgery in elderly people on the risk of hospitalisation due to falls and injuries. Methods A retrospective cohort study was conducted using the Australian Government Department Veterans’ Affairs claims data. All people aged 65 years and above who had first cataract surgery between January 2007...

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Does a Patient-Directed Financial Incentive Affect Patient Choices About Controller Medicines for Asthma? A Discrete Choice Experiment and Financial Impact Analysis

Tracey-Lea Laba, Helen K. Reddel, Nicholas J. Zwar, Guy B. Marks, więcej

PharmacoEconomics > 2019 > 37 > 2 > 227-238

Background In Australia, many patients who are initiated on asthma controller inhalers receive combination inhaled corticosteroid/long-acting beta₂-agonist (ICS/LABA) despite having asthma of sufficiently low severity that ICS-alone would be equally effective and less costly for the government. Methods We conducted a discrete choice experiment (DCE) in a nationally representative sample of adults...

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Assessment of Medication Safety Using Only Dispensing Data

Nicole Pratt, Elizabeth Roughead

Current Epidemiology Reports > 2018 > 5 > 4 > 357-369

Purpose of Review The purpose of this review is to provide an overview of the published studies that have been used to generate evidence on the safety of medicine use when only medication dispensing data are available. Recent Findings Medication dispensing databases are increasingly available for research on large populations, particularly in countries that provide universal coverage for medicines...

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Prevalence of Psychotropic Medicine Use in Australian Children with Autism Spectrum Disorder: A Drug Utilization Study Based on Children Enrolled in the Longitudinal Study of Australian Children

Lotte Rasmussen, Nicole Pratt, Elizabeth Roughead, Anna Moffat

Journal of Autism and Developmental Disorders > 2019 > 49 > 1 > 227-235

Based on data from the Longitudinal Study of Australian Children linked with pharmacy dispensing data from the Australian Government’s Pharmaceutical Benefits Scheme, we calculated the 1-year prevalence of psychotropic medicine supply in children and adolescents with Autism Spectrum Disorder (ASD) as reported by parents in 2014. The majority of children and adolescents with ASD in Australia were not...

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Safety and effectiveness of ‘hospital in the home’ and ‘outpatient parenteral antimicrobial therapy’ in different age groups: A systematic review of observational studies

Shanthy Sriskandarajah, Jodie Hobbs, Elizabeth Roughead, Melissa Ryan, więcej

International Journal of Clinical Practice > 72 > 8 > n/a - n/a

Objective The aim of this study was .to systematically review the published literature of observational studies evaluating the safety and effectiveness of hospital in the home (HITH) and outpatient parenteral antimicrobial therapy (OPAT) in the general population, older people and children. Study design The review included retrospective studies and prospective studies performed on HITH and OPAT...

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Detecting signals of detrimental prescribing cascades from social media

Tao Hoang, Jixue Liu, Nicole Pratt, Vincent W. Zheng, więcej

Artificial Intelligence in Medicine > 2016 > 71 > C > 43-56

Prescribing cascade (PC) occurs when an adverse drug reaction (ADR) is misinterpreted as a new medical condition, leading to further prescriptions for treatment. Additional prescriptions, however, may worsen the existing condition or introduce additional adverse effects (AEs). Timely detection and prevention of detrimental PCs is essential as drug AEs are among the leading causes of hospitalization...

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How common is frailty in older Australians?

Imaina Widagdo, Nicole Pratt, Mary Russell, Elizabeth Roughead

Australasian Journal on Ageing > 34 > 4 > 247 - 251

AimTo determine the prevalence of frailty in a cohort of older Australians. MethodsFrailty status of the 2087 participants of the Australian Longitudinal Study of Ageing was assessed based on the questionnaire responses at the baseline interview. Frailty status and prevalence were assessed using four measures: two unidimensional measures (the Frailty Phenotype and Simplified Frailty Phenotype) and...

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Survival after initiation of androgen deprivation therapy for prostate cancer of Australian men

Svetla Gadzhanova, Elizabeth Roughead

Cancer Epidemiology > 2015 > 39 > 6 > 854-859

To examine duration of use and survival rates of Australian males who initiated androgen deprivation therapy for prostate cancer, including survival rates stratified by the type of the initial androgen deprivation therapy and age at initiation.Cohort study using Australian Government Department of Veterans’ Affairs (DVA) data. Males aged 50 and over initiating androgen deprivation therapy (2008–2010)...

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Use of Medicines with Anticholinergic and Sedative Effect Before and After Initiation of Anti-Dementia Medications

Svetla Gadzhanova, Elizabeth Roughead, Maxine Robinson

Drugs - Real World Outcomes > 2015 > 2 > 1 > 53-60

Background People with dementia may be particularly sensitive to cognitive impairment induced by anticholinergic and sedative medicines. Objective This study aimed to examine if utilisation of medicines with anticholinergic and sedative effects changed before and after initiation of anti-dementia therapy. Methods A retrospective cohort study was conducted using Australian pharmacy...

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Use of prescription medicines in Australian women of child-bearing age

Svetla Gadzhanova, Elizabeth Roughead

BMC Pharmacology and Toxicology > 2015 > 16 > 1 > 1-12

Background This study aimed to examine current utilisation of prescribed medicines amongst Australian women of child-bearing age, with a particular focus on the extent of use of medicines in Category D and X risk groups, which are moderate and high risk teratogens, respectively. The use of those medicines may pose risk of birth defects in pregnant women. Methods A retrospective cross-sectional study...

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Regulatory withdrawal of medicines marketed with uncertain benefits: the bevacizumab case study

Agnes Vitry, Tuan Nguyen, Vikky Entwistle, Elizabeth Roughead

Journal of Pharmaceutical Policy and Practice > 2015 > 8 > 1 > 1-11

Background Withdrawal of conditional regulatory approval or subsidization of new medicines when subsequent evidence does not confirm early trial results may not be well understood or accepted by the public. Objectives We present a case study of the US Food and Drug Administration (FDA)’s decision to withdraw the indication of bevacizumab for the treatment of advanced breast cancer and include an...

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Managed entry agreements for pharmaceuticals in Australia

Agnes Vitry, Elizabeth Roughead

Health policy > 2014 > 117 > 3 > 345-352

In Australia, a number of managed entry agreements have been developed to enable national coverage of new medicines. Non-outcome based agreements are usually pricing arrangements that involve price or volume rebate agreements. In February 2013, there were at least 71 special pricing arrangements in place, including 26 for medicines restricted to use in hospitals. Health outcome based agreements can...

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New users of antidepressant medications: first episode duration and predictors of discontinuation

Christine Y. Lu, Elizabeth Roughead

European Journal of Clinical Pharmacology > 2012 > 68 > 1 > 65-71

Purpose Clinical guidelines recommend that antidepressant treatment should be continued for at least 6 months. We examined persistence in patients initiated on an antidepressant medication and factors associated with treatment cessation. Methods We conducted a cohort study of antidepressant initiators in the Australian veteran population. Patients included were those who had filled at least one...

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Charlson and Rx-Risk comorbidity indices were predictive of mortality in the Australian health care setting

Christine Y. Lu, John Barratt, Agnes Vitry, Elizabeth Roughead

Journal of Clinical Epidemiology > 2011 > 64 > 2 > 223-228

To compare the performance of Charlson index and Rx-Risk score using data from Australian Department of Veterans' Affairs.A study of older adults (N=94,714) who had both Charlson and Rx-Risk scores based on their hospital diagnoses and prescription medication dispensings during the baseline year (January 2005–December 2005). Predictive ability of 1-year and 3-year mortality was compared by Akaike...

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Factors associated with choice of antipsychotic treatment in elderly veterans: potential confounders for observational studies

Nicole Pratt, Elizabeth Roughead, Amy Salter, Philip Ryan

Australian and New Zealand Journal of Public Health > 34 > 6 > 589 - 593

Background: Antipsychotics are commonly used in the elderly despite limited efficacy and safety data from randomised controlled trials. Observational comparative safety studies of antipsychotics vary, which may be due to confounding. Objective: To compare the characteristics of typical and atypical antipsychotic initiators. Methods: Using the Australian Government...

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Patient specific prescriber education and feedback is effective in reducing use of antipsychotics in the elderly

Michael Woodward, Elizabeth Roughead, Andrew Gilbert, Lisa Kalisch

Alzheimer's & Dementia > 2010 > 6 > 4(S) > S588

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Acta Ophthalmologica (1)
Alzheimer's & Dementia (1)
Artificial Intelligence in Medicine (1)
Australasian Journal on Ageing (1)
Australian and New Zealand Journal of Public Health (1)
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Current Epidemiology Reports (1)
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International Journal of Clinical Practice (1)
Journal of Autism and Developmental Disorders (1)
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