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Objective
In gout, hyperuricemia promotes urate crystal deposition, which stimulates the NLRP3 inflammasome and interleukin‐1β (IL‐1β)–mediated arthritis. Incident gout without background hyperuricemia is rarely reported. To identify hyperuricemia‐independent mechanisms driving gout incidence and progression, we characterized erosive urate crystalline inflammatory arthritis in a young female patient...