Search results for: Elias Olafsson

Items from 1 to 8 out of 8 results

article

Sudden unexpected death in epilepsy. A nationwide population‐based study

Anna B. Einarsdottir, Olafur Sveinsson, Elias Olafsson

Epilepsia > 60 > 11 > 2174 - 2181

Objective The incidence of sudden unexpected death in epilepsy (SUDEP) varies between studies. We determined the incidence of SUDEP in the entire Icelandic population during a 20‐year period. Methods All individuals in Iceland with epilepsy who died unexpectedly from January 1, 1991 through December 31, 2010 were included. Case ascertainment was based on autopsies, reimbursement for antiepileptic...

article

Antiepileptic drugs are associated with central hypothyroidism

Margret Jona Einarsdottir, Elias Olafsson, Helga Agusta Sigurjonsdottir

Acta Neurologica Scandinavica > 139 > 1 > 64 - 69

Objective Studies in children have shown an increased frequency of central hypothyroidism (CH) with long‐term use of antiepileptic drugs (AEDs). The aim of this study was to search for CH in adults treated with AEDs and find whether the type of AEDs used matters. Materials and methods Adult epileptic patients treated at the neurology outpatient clinic at Landspitali University Hospital (LSH) from...

article

Incidence and outcome of Guillain‐Barré syndrome in Iceland: A population‐based study

Brynhildur Hafsteinsdóttir, Elías Ólafsson, Finnbogi Jakobsson

Acta Neurologica Scandinavica > 138 > 5 > 454 - 458

Objective In this study, we determine the incidence and outcomes of Guillain‐Barré syndrome (GBS) in Iceland over a 20‐year period. Method Cases were identified from the records of both referral hospitals in the country. All cases met the Brighton Criteria for GBS. Disability was assessed at diagnosis, peak of symptoms, discharge, and follow‐up using the Guillain‐Barré Disability Scale. Results...

article

Parenchymal cystatin C focal deposits and glial scar formation around brain arteries in Hereditary Cystatin C Amyloid Angiopathy

Asbjorg Osk Snorradottir, Helgi J. Isaksson, Stephan A. Kaeser, Angelos A. Skodras, more

Brain Research > 2015 > 1622 > Complete > 149-162

Hereditary Cystatin C Amyloid Angiopathy (HCCAA) is an amyloid disorder in Icelandic families caused by an autosomal dominant mutation in the cystatin C gene. Mutant cystatin C forms amyloid deposits in brain arteries and arterioles which are associated with changes in the arterial wall structure, notably deposition of extracellular matrix proteins. In this post-mortem study we examined the neuroinflammatory...

article

Deposition of collagen IV and aggrecan in leptomeningeal arteries of hereditary brain haemorrhage with amyloidosis

Asbjorg Osk Snorradottir, Helgi J. Isaksson, Stephan A. Kaeser, Angelos A. Skodras, more

Brain Research > 2013 > 1535 > Complete > 106-114

Hereditary Cystatin C Amyloid Angiopathy (HCCAA) is a rare genetic disease in Icelandic families caused by a mutation in the cystatin C gene, CST3. HCCAA is classified as a cerebral amyloid angiopathy and mutant cystatin C forms amyloid deposits in cerebral arteries resulting in fatal haemorrhagic strokes in young adults. The aetiology of HCCAA pathology is not clear and there is, at present, no animal...

article

Epilepsy and suicide risk

Dale C Hesdorffer, W Allen Hauser, Elias Olafsson, Petur Ludvigsson, more

The Lancet Neurology > 2007 > 6 > 10 > 847

article

Co-occurrence of major depression or suicide attempt with migraine with aura and risk for unprovoked seizure

Dale C. Hesdorffer, Pétur Lúðvígsson, W. Allen Hauser, Elías Ólafsson, more

Epilepsy Research > 2007 > 75 > 2-3 > 220-223

We hypothesized and found that the co-occurrence of migraine with aura (MA) with major depression (MD) or with suicide attempt (SA) increases the risk for developing unprovoked seizure more than these conditions alone. Number of conditions showed a linear relationship to seizure risk. This may reflect a new condition cluster defined by MA, MD, SA and unprovoked seizures. Identifying the biological...

article

Incidence of unprovoked seizures and epilepsy in Iceland and assessment of the epilepsy syndrome classification: a prospective study

Elias Olafsson, Petur Ludvigsson, Gunnar Gudmundsson, Dale Hesdorffer, more

The Lancet Neurology > 2005 > 4 > 10 > 627-634

No population-based incidence studies of epilepsy have studied syndrome classification from the outset. We prospectively studied the incidence of a single unprovoked seizure and epilepsy in the population of Iceland, and applied the syndrome classification endorsed by the International League Against Epilepsy to this population. We used a nationwide surveillance system to prospectively identify...

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Keywords

EPILEPSY (2)
HEREDITARY CYSTATIN C AMYLOID ANGIOPATHY (2)
INCIDENCE (2)
POPULATION‐BASED (2)
ANTIEPILEPTIC DRUGS (1)
CARBAMAZEPINE (1)
CASE–CONTROL STUDY (1)
CYSTATIN C (1)
CYSTATIN C DISTRIBUTION (1)
DEPRESSION (1)
EPIDEMIOLOGY (1)
EXTRACELLULAR MATRIX DEPOSITION (1)
FOCAL DEPOSITS (1)
GLIAL SCAR (1)
GUILLAIN‐BARRÉ SYNDROME (1)
HYPOPITUITARISM (1)
HYPOTHYROIDISM (1)
ICELAND (1)
IMMUNOHISTOCHEMISTRY (1)
MIGRAINE (1)
NEUROINFLAMMATION (1)
OXCARBAZEPINE (1)
SUDEP (1)
UNPROVOKED SEIZURE (1)
VASCULAR PATHOLOGY (1)
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Elsevier (5)
Wiley (3)

INFONA - science communication portal

Search results for: Elias Olafsson

Sudden unexpected death in epilepsy. A nationwide population‐based study

Antiepileptic drugs are associated with central hypothyroidism

Incidence and outcome of Guillain‐Barré syndrome in Iceland: A population‐based study

Parenchymal cystatin C focal deposits and glial scar formation around brain arteries in Hereditary Cystatin C Amyloid Angiopathy

Deposition of collagen IV and aggrecan in leptomeningeal arteries of hereditary brain haemorrhage with amyloidosis

Epilepsy and suicide risk

Co-occurrence of major depression or suicide attempt with migraine with aura and risk for unprovoked seizure

Incidence of unprovoked seizures and epilepsy in Iceland and assessment of the epilepsy syndrome classification: a prospective study

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