Search results for: John M. Jakicic
article
Contemporary antiobesity medications (AOMs) are highly efficacious for the treatment of obesity and obesity‐related comorbidities. Given this effectiveness, lifestyle factors within the context of AOM treatments need to refocus and move away from efforts to enhance weight loss. Rather, lifestyle considerations should pivot to being complementary to the benefits realized with AOM treatment and be redirected...
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Objective
This study aimed to determine whether novel biomarkers of cardiometabolic health improve in response to a 12‐month behavioral weight‐loss intervention and to compare benefits of diet alone with diet plus physical activity for these biomarkers.
Methods
Participants (N = 374) were randomized to either diet alone (DIET), diet plus 150 min/wk of prescribed moderate‐intensity physical activity...
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Diabetes, Obesity and Metabolism > 24 > 7 > 1206 - 1215
Aims
Long‐term data from randomized clinical trials comparing metabolic (bariatric) surgery versus a medical/lifestyle intervention for treatment of patients with obesity/overweight and type 2 diabetes (T2D) are lacking. The Alliance of Randomized Trials of Medicine vs Metabolic Surgery in Type 2 Diabetes (ARMMS‐T2D) is a consortium of four randomized trials designed to compare long‐term efficacy...
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Objective
The primary aim of this study was to examine the change in left ventricular mass (LVM) in adults with overweight or obesity in response to a behavioral weight‐loss intervention, with variable physical activity (PA) prescriptions.
Methods
A total of 383 adults were randomized to a 12‐month intervention of diet modification (DIET), DIET plus 150 min/wk of PA (DIET+MODPA), or DIET plus prescription...
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Objective
Weight stigma is associated with impaired health, attributed in part to reductions in health‐promoting behaviors. This review analyzed evidence of the association between weight stigma and physical activity (PA) in adults and youth.
Methods
Three databases were searched for terms related to weight stigma and PA. Eligible studies reported the quantitative association between at least one...
article
The Look AHEAD Research Group,
Thomas A. Wadden,
Ariana M. Chao,
Harelda Anderson,
more
Objective
The Action for Health in Diabetes (Look AHEAD) study previously reported that intensive lifestyle intervention (ILI) reduced incident depressive symptoms and improved health‐related quality of life (HRQOL) over nearly 10 years of intervention compared with a control group (the diabetes support and education group [DSE]) in participants with type 2 diabetes and overweight or obesity. The...
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article
Psychophysiology > 58 > 7 > n/a - n/a
The Fitness Versus Body Fat Hypothesis argues that cardiorespiratory fitness (CRF) plays a more important role in cardiovascular health than adiposity. It remains poorly understood whether CRF or adiposity accounts for a greater amount of variation in measures of brain health. We examined the contribution of CRF, adiposity, and their interaction with hippocampal structure. This study included 124...
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Liver Transplantation > 27 > 4 > 502 - 512
Preserved physical function is key for successful liver transplantation (LT); however, prehabilitation strategies are underdeveloped. We created a smartphone application (app), EL‐FIT (Exercise and Liver FITness), to facilitate exercise training in end‐stage liver disease (ESLD). In this feasibility study, we tested EL‐FIT app usage and the accuracy of physical activity data transfer and obtained...
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Although many persons with obesity can lose weight by lifestyle (diet and physical activity) therapy, successful long‐term weight loss is difficult to achieve, and most people who lose weight regain their lost weight over time. The neurohormonal, physiological, and behavioral factors that promote weight recidivism are unclear and complex. The National Institute of Diabetes and Digestive and Kidney...
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Objective
This study examined the feasibility and comparison of two styles of yoga within the context of a standard behavioral weight‐loss intervention (SBWI).
Methods
Fifty adults with obesity (BMI: 31.3 ± 3.8 kg/m2) participated in this 6‐month study that included a SBWI and a calorie‐ and fat‐reduced diet. Randomization was to restorative Hatha (SBWI+RES) or Vinyasa (SBWI+VIN) yoga. Yoga was...
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Look AHEAD Research Group,
Hsin‐Chieh Yeh,
John P. Bantle,
Maria Cassidy‐Begay,
more
Objective
This study was designed to determine whether intensive lifestyle intervention (ILI) aimed at weight loss lowers cancer incidence and mortality.
Methods
Data from the Look AHEAD trial were examined to investigate whether participants randomized to ILI designed for weight loss would have reduced overall cancer incidence, obesity‐related cancer incidence, and cancer mortality, as compared...
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Look AHEAD Research Group,
Ariana M. Chao,
Thomas A. Wadden,
Robert I. Berkowitz,
more
Objective
This study evaluated weight changes after cessation of the 10‐year intensive lifestyle intervention (ILI) in the Look AHEAD (Action for Health in Diabetes) study. It was hypothesized that ILI participants would be more likely to gain weight during the 2‐year observational period following termination of weight‐loss–maintenance counseling than would participants in the diabetes support and...
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Look AHEAD Research Group,
Cora E. Lewis,
John P. Bantle,
Alain G. Bertoni,
more
Objective
To examine the effects of an intensive lifestyle intervention (ILI) on cardiovascular disease (CVD), the Action for Health in Diabetes (Look AHEAD) trial randomized 5,145 participants with type 2 diabetes and overweight/obesity to a ILI or diabetes support and education. Although the primary outcome did not differ between the groups, there was suggestive evidence of heterogeneity for prespecified...
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Sport Sciences for Health > 2019 > 15 > 3 > 647-658
Purpose It is important to understand acute dose-response relationships on cardiovascular health and brain health. Thus, we evaluated the acute effects of 10- and 30-min exercise bout on blood pressure (BP), pulse wave velocity (PWV) and cerebral blood flow velocity (CBFv). Methods Fifteen adults (mean age 45.4 ± 8.9 years, 87% female) participated in this randomized crossover study comprised of...
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Objective
The Action for Health in Diabetes (Look AHEAD) research study was a randomized trial comparing the effects of an intensive lifestyle intervention (ILI) versus a diabetes support and education (DSE) control group in adults with type 2 diabetes and overweight or obesity. Functional magnetic resonance imaging was used to determine whether neural food cue reactivity differed for these groups...
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Objective
The goal of the present study was to deconstruct the 17 treatment arms used in the Early Adult Reduction of weight through LifestYle (EARLY) weight management trials.
Methods
Intervention materials were coded to reflect behavioral domains and behavior change techniques (BCTs) within those domains planned for each treatment arm. The analytical hierarchy process was employed to determine...
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Objective
This study examined end‐of‐trial health outcomes in participants in the Action for Health in Diabetes (Look AHEAD) trial who had bariatric surgery during the approximately 10‐year randomized intervention.
Methods
Data were obtained from the Look AHEAD public access database of 4,901 individuals with type 2 diabetes and overweight/obesity who were assigned to intensive lifestyle intervention...
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Objective
The aim of this study was to examine the association between the amount, intensity, and pattern of steps·day−1 with weight loss.
Methods
Participants (N = 260; age = 42.8 ± 8.9 y; BMI = 32.8 ± 3.5 kg/m2) completed an 18‐month weight‐loss intervention that included a calorie‐restricted diet and prescribed physical activity. Participants were categorized by 18‐month weight loss as weight...
