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Bone regeneration is a vital clinical challenge in massive or complicated bone defects. Recently, bone tissue engineering has come to the fore to meet the demand for bone repair with various innovative materials. However, the reported materials usually cannot satisfy the requirements, such as ideal mechanical and osteogenic properties, as well as biocompatibility at the same time. Mg‐based biomaterials...
Infected Tissue Regeneration
In article number 2205941, Xibo Pei, Jian Wang, and co‐workers report a silver nanoparticle (AgNPs) modified metal‐organic‐framework nanosystem (AgNPs@MOFs) with enhanced photodynamic efficiency and chemotherapy ability for infected tissue regeneration. The photodynamic performance under visible light disrupts bacteria translation process. The chemotherapy process causes...
Drug‐resistant bacterial infection impairs tissue regeneration and is a challenging clinical problem. Metal–organic frameworks (MOFs)‐based photodynamic therapy (PDT) opens up a new era for antibiotic‐free infection treatment. However, the MOF‐based PDT normally encounters limited photon absorbance under visible light and notorious recombination of photogenerated holes and electrons, which significantly...
The rapid spread of drug‐resistant pathogens threatens human health. To address the current antibacterial dilemma, the development of antibiotic‐free strategies using nanotechnology is imperative. In this study, silver nanoparticles (Ag‐P&C NPs) with pH‐sensitive charge reversal and self‐aggregation capacities are successfully synthesized. In the acidic microenvironment of bacterial biofilms,...
We have witnessed abundant breakthroughs in research on the bio-applications of graphene family materials in current years. Owing to their nanoscale size, large specific surface area, photoluminescence properties, and antibacterial activity, graphene family materials possess huge potential for bone tissue engineering, drug/gene delivery, and biological sensing/imaging applications. In this review,...
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