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Summary A 50+ SPF sunscreen decreased significantly cutaneous vitamin D production following a single narrow-band (nb)UVB exposure, independently from the body surface area exposed. In contrast, the circulating 25(OH)D3 levels were only minimally affected. It is probable that another endogenous source of precursors is selected when skin-originated precursors are lacking. Purpose Sunscreen use, highly...
Burn patients are at risk of vitamin D (VD) deficiency and may benefit from its pleiotropic effects as soon as acute phase. Aim of this observational study was to assess effects of a cholecalciferol (VD3) bolus on VD status in adult burn patients (Group B, GB) after admission, compared to healthy subjects (Group H, GH).Both groups received an oral dose of 100,000IU VD3. Blood samples were collected...
Standardization of immunoassays for 25(OH)-vitamin D determination is a major problem in clinical practice. A worldwide standardization program has started to address this and will reduce the bias observed between immunoassays. We aimed to calibrate 5 immunoassays on a LC–MS/MS traceable to the SRM 2972 and the ID-LC–MS/MS 25(OH)D Reference Method Procedure to see if the re-standardization would be...
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