Search results for: Paola Viganò

Items from 1 to 20 out of 95 results

article

Male and female human papilloma virus infection and assisted reproductive technology outcomes: A comprehensive assessment from prevalence in semen to obstetric outcomes

Giorgia Carullo, Sara Uceda Renteria, Ludovica Basili, Davide Marinello, more

Journal of Medical Virology > 96 > 10 > n/a - n/a

Infertility, affecting approximately 16% of the global population, has led to increased reliance on reproductive medicine. The impact of human papillomavirus (HPV) infection in one or both partners on outcomes of Assisted Reproduction Technologies (ART) remains unclear. This prospective cohort study aimed to evaluate prevalence and effects of HPV infection in subjects and couples candidates to ART...

article

Probability of second live birth after first natural and medically assisted reproduction‐mediated live birth: A historical cohort study

Giovanna Esposito, Fabio Parazzini, Paola Viganò, Matteo Franchi, more

Acta Obstetricia et Gynecologica Scandinavica > 103 > 1 > 121 - 128

Introduction Evidence on the role of medically assisted reproduction (MAR) in achieving the desired number of children is very limited. The aim of the current investigation was to assess the probability and the mode of conception of a second live birth according to the mode of conception of the first one. Material and methods This historical cohort study was based on administrative data from regional...

article

Varicocoele embolization with sclerosing agents leads to lower radiation exposure and procedural costs than coils: Data from a real‐life before and after study

Luca Boeri, Irene Fulgheri, Marco Cristina, Pierpaolo Biondetti, more

Andrology > 10 > 4 > 694 - 701

Objectives To investigate clinical outcomes, radiation exposure and procedural costs associated with percutaneous varicocoele embolization using coils and sclerosing agents (SAs) in a cohort of young‐adult men. Materials and methods Data from consecutive men treated with percutaneous varicocoele embolization using coils and SA between 2017 and 2021 were analyzed. The allocation was based on a change...

article

Infertile couples still undergo assisted reproductive treatments without initial andrological evaluation in the real‐life setting: A failure to adhere to guidelines?

Edoardo Pozzi, Luca Boeri, Luigi Candela, Paolo Capogrosso, more

Andrology > 9 > 6 > 1843 - 1852

Background The EAU guidelines on male sexual and reproductive health state that both partners of the infertile couple should undergo simultaneous investigation. Objectives To assess the prevalence and the characteristics of infertile men who were referred for an andrological evaluation after failed attempts of Assisted Reproductive Technology (ART) with those who were evaluated at the beginning...

article

Male factor infertility trends throughout the last 10 years: Report from a tertiary‐referral academic andrology centre

Giuseppe Fallara, Walter Cazzaniga, Luca Boeri, Paolo Capogrosso, more

Andrology > 9 > 2 > 610 - 617

Background Trends of male factor causes of couples' infertility over time have been poorly investigated. Objective We investigated trends in the causes of pure male factor infertility (MFI) throughout the last 10 years in a tertiary‐referral academic andrology center. Material and Methods Baseline characteristics at first presentation from a cohort of 1647 consecutive male factor infertility...

article

Normal sperm parameters per se do not reliably account for fertility: A case–control study in the real‐life setting

Luca Boeri, Federico Belladelli, Paolo Capogrosso, Walter Cazzaniga, more

Andrologia > 53 > 1 > n/a - n/a

A proportion of men are infertile despite having normal medical history/physical examination and normal semen analysis. We aimed to assess whether normal sperm parameters per se account for male factor fertility. 1,957 infertile men were compared with 103 age‐comparable fertile controls. Semen analysis was based on 2010 World Health Organization reference criteria. Of all, 12.1% of infertile men and...

article

Effect of vitamin D supplementation on assisted reproduction technology (ART) outcomes and underlying biological mechanisms: protocol of a randomized clinical controlled trial. The “supplementation of vitamin D and reproductive outcome” (SUNDRO) study

Alessio Paffoni, Edgardo Somigliana, Veronica Sarais, Stefania Ferrari, more

BMC Pregnancy and Childbirth > 2019 > 19 > 1 > 1-9

Background Vitamin D plays an important role in human physiology and pathology. The receptor for vitamin D regulates 0.5–5% of the human genome. Accordingly, vitamin D insufficiency has been shown to increase the risk of several diseases. In recent years, based on growing evidence, on a role of vitamin D has been also postulated in reproductive health both in animals and humans, especially in female...

article

Undiagnosed prediabetes is highly prevalent in primary infertile men – results from a cross‐sectional study

Luca Boeri, Paolo Capogrosso, Eugenio Ventimiglia, Filippo Pederzoli, more

BJU International > 123 > 6 > 1070 - 1077

Objective To study the prevalence and the risk associated with prediabetes (PreDM) in primary infertile men. Patients and methods Data from 744 infertile men were analysed. Health‐significant comorbidities were scored with the Charlson Comorbidity Index (CCI). Serum hormones were measured in every man. Semen analysis was based on 2010 World Health Organization (WHO) reference criteria. PreDM was...

article

The duration of infertility affects semen parameters in primary infertile men: results of a single‐centre, cross‐sectional study

Luca Boeri, Eugenio Ventimiglia, Paolo Capogrosso, Angela Pecoraro, more

BJU International > 123 > 5 > 891 - 898

Objective To assess the relationship between the duration of infertility (DI) and the seminal parameters of a cohort of White‐European primary infertile men. Patients and Methods Data from 1644 infertile men were analysed. Patients were grouped according to the self‐reported DI into 12‐month time frames. Semen analysis values were assessed based on 2010 World Health Organisation reference criteria...

article

Assessment of pre‐implantation genetic testing for embryo aneuploidies: A SWOT analysis

Alessandra Alteri, Laura Corti, Ana M. Sanchez, Elisa Rabellotti, more

Clinical Genetics > 95 > 4 > 479 - 487

The recently re‐named pre‐implantation genetic testing for determining embryo aneuploidies (PGT‐A) is presently very popular although its acceptance by the scientific community is controversial. This approach still encounters drawbacks. This paper uses a SWOT (strengths, weaknesses, opportunities and threats) analysis to discuss salient points to be considered when examining the pre‐implantation genetic...

article

Testosterone therapy for women with poor ovarian response undergoing IVF: a meta-analysis of randomized controlled trials

Marco Noventa, Amerigo Vitagliano, Alessandra Andrisani, Mija Blaganje, more

Journal of Assisted Reproduction and Genetics > 2019 > 36 > 4 > 673-683

Purpose The aim of the present systematic review and meta-analysis was to summarize evidence on the effectiveness of testosterone supplementation for poor ovarian responders (POR) on IVF outcomes. The primary outcome was live birth rate (LBR); secondary outcomes were clinical pregnancy rate (CPR), miscarriage rate (MR), total and MII oocytes, and total embryos. Methods This meta-analysis of randomized...

article

Contrast-enhanced ultrasound for ovary assessment in a murine model: preliminary findings on the protective role of a gonadotropin-releasing hormone analogue from chemotherapy-induced ovarian damage

Massimo Venturini, Alice Bergamini, Laura Perani, Ana Maria Sanchez, more

European Radiology Experimental > 2018 > 2 > 1 > 1-9

The prolonged, gonadotoxic effect of chemotherapy can finally lead to infertility in female cancer survivors. There is controversial evidence regarding the protective role of gonadotropin-releasing hormone analogue (GnRH-a) on chemotherapy-induced ovarian damage. In the present study on a murine model, ultrasound (US) and contrast-enhanced US (CEUS) were firstly used to characterise ovarian glands...

article

Abnormal sperm concentration and motility as well as advanced paternal age compromise early embryonic development but not pregnancy outcomes: a retrospective study of 1266 ICSI cycles

Alessandro Bartolacci, Luca Pagliardini, Sofia Makieva, Andrea Salonia, more

Journal of Assisted Reproduction and Genetics > 2018 > 35 > 10 > 1897-1903

Purpose To investigate the effect of sperm concentration, motility and advanced paternal age on reproductive outcomes. Methods A retrospective analysis of 1266 intracytoplasmic sperm injection (ICSI) cycles between 2013 and 2017. The cohort was divided into four groups according to semen concentration based on the WHO criteria (2010): group A (conc. <1 M/ml), group B (1 ≤ conc. <5 M/ml), group...

article

Revisiting embryo assisted hatching approaches: a systematic review of the current protocols

Alessandra Alteri, Paola Viganò, Ahmad Abu Maizar, Luca Jovine, more

Journal of Assisted Reproduction and Genetics > 2018 > 35 > 3 > 367-391

Zona pellucida (ZP) manipulation, termed “assisted hatching” (AH), has been introduced in order to favor embryo hatching and ultimately improve assisted reproductive technology success but with poor proofs of safety and biological plausibility. We herein provide a systematic review of clinical outcomes following the application of different methods of ZP manipulation on fresh or frozen/thawed embryos...

article

Repeated implantation failure at the crossroad between statistics, clinics and over-diagnosis

Edgardo Somigliana, Paola Vigano, Andrea Busnelli, Alessio Paffoni, more

Reproductive BioMedicine Online > 2018 > 36 > 1 > 32-38

The most common definition of repeated implantation failure (RIF) is the failure to obtain a clinical pregnancy after three completed IVF cycles. This definition, however, may lead to misuse of the diagnosis. To disentangle this, we set up a mathematical model based on the following main assumptions: rate of success of IVF constant and set at 30%; and RIF postulated to be a dichotomous condition (yes...

article

Obstetrical complications of endometriosis, particularly deep endometriosis

Umberto Leone Roberti Maggiore, Annalisa Inversetti, Matteo Schimberni, Paola Viganò, more

Fertility and Sterility > 2017 > 108 > 6 > 895-912

Over the past few years, a new topic in the field of endometriosis has emerged: the potential impact of the disease on pregnancy outcomes. This review aims to summarize in detail the available evidence on the relationship between endometriosis, particularly deep endometriosis (DE), and obstetrical outcomes. Acute complications of DE, such as spontaneous hemoperitoneum, bowel perforation, and uterine...

article

Reply to Rodolfo Montironi, Silvia Gasparrini, Antonio Lopez-Beltran, et al's Letter to the Editor re: Umberto Leone Roberti Maggiore, Simone Ferrero, Massimo Candiani, et al. Bladder Endometriosis: A Systematic Review of Pathogenesis, Diagnosis, Treatment, Impact on Fertility, and Risk of Malignant Transformation. Eur Urol 2017;71:790–807. Benign Müllerian Lesions in the Urinary Bladder: Endometriosis, Endocervicosis, Endosalpingiosis, and Müllerianosis

Umberto Leone Roberti Maggiore, Simone Ferrero, Massimo Candiani, Edgardo Somigliana, more

European Urology > 2017 > 72 > 5 > e142

article

Sleep disturbances and semen quality in an Italian cross sectional study

Paola Viganò, Francesca Chiaffarino, Viviana Bonzi, Andrea Salonia, more

Basic and Clinical Andrology > 2017 > 27 > 1 > 1-6

Introduction In order to obtain information about the relationship between sleep disturbances and sperm parameters, we analyzed data from a study conducted in a Italian Fertility Clinic, in men of couples seeking help for infertility. Patients and methods Male partners with or without a medical history of reproductive organ diseases (cryptorchidism, varicocele, orchitis, testicular torsion) were...

article

Is the oocyte quality affected by endometriosis? A review of the literature

Ana Maria Sanchez, Valeria Stella Vanni, Ludovica Bartiromo, Enrico Papaleo, more

Journal of Ovarian Research > 2017 > 10 > 1 > 1-11

Endometriosis is an estrogen-dependent chronic inflammatory condition that affects women in their reproductive period causing infertility and pelvic pain. The disease, especially at the ovarian site has been shown to have a detrimental impact on ovarian physiology. Indeed, sonographic and histologic data tend to support the idea that ovarian follicles of endometriosis patients are decreased in number...

article

Coffee and caffeine intake and male infertility: a systematic review

Elena Ricci, Paola Viganò, Sonia Cipriani, Edgardo Somigliana, more

Nutrition Journal > 2017 > 16 > 1 > 1-14

Background Semen quality, a predictor of male fertility, has been suggested declining worldwide. Among other life style factors, male coffee/caffeine consumption was hypothesized to influence semen parameters, but also sperm DNA integrity. To summarize available evidence, we performed a systematic review of observational studies on the relation between coffee/caffeine intake and parameters of male...

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INFONA - science communication portal

Search results for: Paola Viganò

Male and female human papilloma virus infection and assisted reproductive technology outcomes: A comprehensive assessment from prevalence in semen to obstetric outcomes

Probability of second live birth after first natural and medically assisted reproduction‐mediated live birth: A historical cohort study

Varicocoele embolization with sclerosing agents leads to lower radiation exposure and procedural costs than coils: Data from a real‐life before and after study

Infertile couples still undergo assisted reproductive treatments without initial andrological evaluation in the real‐life setting: A failure to adhere to guidelines?

Male factor infertility trends throughout the last 10 years: Report from a tertiary‐referral academic andrology centre

Normal sperm parameters per se do not reliably account for fertility: A case–control study in the real‐life setting

Effect of vitamin D supplementation on assisted reproduction technology (ART) outcomes and underlying biological mechanisms: protocol of a randomized clinical controlled trial. The “supplementation of vitamin D and reproductive outcome” (SUNDRO) study

Undiagnosed prediabetes is highly prevalent in primary infertile men – results from a cross‐sectional study

The duration of infertility affects semen parameters in primary infertile men: results of a single‐centre, cross‐sectional study

Assessment of pre‐implantation genetic testing for embryo aneuploidies: A SWOT analysis

Testosterone therapy for women with poor ovarian response undergoing IVF: a meta-analysis of randomized controlled trials

Contrast-enhanced ultrasound for ovary assessment in a murine model: preliminary findings on the protective role of a gonadotropin-releasing hormone analogue from chemotherapy-induced ovarian damage

Abnormal sperm concentration and motility as well as advanced paternal age compromise early embryonic development but not pregnancy outcomes: a retrospective study of 1266 ICSI cycles

Revisiting embryo assisted hatching approaches: a systematic review of the current protocols

Repeated implantation failure at the crossroad between statistics, clinics and over-diagnosis

Obstetrical complications of endometriosis, particularly deep endometriosis

Sleep disturbances and semen quality in an Italian cross sectional study

Is the oocyte quality affected by endometriosis? A review of the literature

Coffee and caffeine intake and male infertility: a systematic review

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