Search results for: Trond Sand

Items from 1 to 20 out of 44 results

article

Contact‐free radar recordings of body movement can reflect ultradian dynamics of sleep

Hanne Siri Amdahl Heglum, Henning Johannes Drews, Håvard Kallestad, Daniel Vethe, more

Journal of Sleep Research > 31 > 6 > n/a - n/a

This work aimed to evaluate if a contact‐free radar sensor can be used to observe ultradian patterns in sleep physiology, by way of a data processing tool known as Locomotor Inactivity During Sleep (LIDS). LIDS was designed as a simple transformation of actigraphy recordings of wrist movement, meant to emphasise and enhance the contrast between movement and non‐movement and to reveal patterns of low...

article

Validation of questionnaires for restless legs syndrome in the general population: the Trøndelag Health Study (HUNT)

James Filosa, Petter Moe Omland, Knut Hagen, Knut Langsrud, more

Journal of Sleep Research > 31 > 5 > n/a - n/a

Questionnaires for restless legs syndrome have rarely been validated against face‐to‐face interviews in the general population. We aimed to validate the modified Norwegian, seven‐item Cambridge‐Hopkins restless legs syndrome questionnaire and a single diagnostic question for restless legs syndrome. We also aimed to stratify validity at 65 years of age. Among a random sample of 1,201 participants from...

article

Which combined nerve conduction study scores are best suited for polyneuropathy in diabetic patients?

Øystein Dunker, Kristian Bernhard Nilsen, Sandra Elise Olsen, Bjørn Olav Åsvold, more

Muscle & Nerve > 65 > 2 > 171 - 179

Introduction/Aims Nerve conduction studies (NCS) are widely used in diagnosing diabetic polyneuropathy. Combining the Z scores of several measures (Z‐compounds) may improve diagnostics by grading abnormality. We aimed to determine which combination of nerves and measures is best suited for studies of diabetic polyneuropathy. Methods Sixty‐eight patients with type 1 diabetes and 35 controls were...

article

Daily associations between sleep and pain in patients with chronic musculoskeletal pain

Karin Abeler, Svein Bergvik, Trond Sand, Oddgeir Friborg

Journal of Sleep Research > 30 > 4 > n/a - n/a

Patients with chronic pain commonly report sleep problems, and the evidence for a relationship between sleep disturbance and pain seems robust. The day‐to‐day associations between these constructs are less well studied, particularly with objective sleep measures such as actigraphy. Moreover, the concurrent presence of negative affective symptoms, as well as seasonality effects at extreme latitudes...

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Validation of insomnia questionnaires in the general population: The Nord‐Trøndelag Health Study (HUNT)

James Filosa, Petter Moe Omland, Knut Langsrud, Knut Hagen, more

Journal of Sleep Research > 30 > 1 > n/a - n/a

The primary aim was to validate questionnaire‐based insomnia diagnoses from a modified Karolinska Sleep Questionnaire (KSQ) and the Insomnia Severity Index (ISI), by age category (< or >65 years), against a semi‐structured face‐to‐face interview. Secondary aims were to split validity by diagnostic certainty of the interview and to compare prevalence estimates of questionnaire‐ and interview‐based...

article

Sleep restriction does not potentiate nocebo‐induced changes in pain and cortical potentials

Anbjørn Ree, Kristian Bernhard Nilsen, Stein Knardahl, Trond Sand, more

European Journal of Pain > 24 > 1 > 110 - 121

Background The increased pain sensitivity following reduced sleep may be related to changes in cortical processing of nociceptive stimuli. Expectations shape pain perception and can inhibit (placebo) or enhance (nocebo) pain. Sleep restriction appears to enhance placebo responses; however, whether sleep restriction also affects nocebo responses remains unknown. The aim of the present study was to...

article

Cognitive performance in DSWPD patients upon awakening from habitual sleep compared with forced conventional sleep

Brandy Solheim, Alexander Olsen, Håvard Kallestad, Knut Langsrud, more

Journal of Sleep Research > 28 > 5 > n/a - n/a

Difficult early morning awakening is one of the defining symptoms of delayed sleep–wake phase disorder. It is accompanied by low cognitive arousal and drowsiness resulting in difficulty concentrating and focusing attention upon awakening. We designed the current study to quantitate cognitive performance (i.e. omissions, commissions, reaction time [average and variability]) and cognitive domains (i...

article

Fluctuations of sensorimotor processing in migraine: a controlled longitudinal study of beta event related desynchronization

Martin Syvertsen Mykland, Marte Helene Bjørk, Marit Stjern, Petter Moe Omland, more

The Journal of Headache and Pain > 2019 > 20 > 1 > 1-10

Background The migraine brain seems to undergo cyclic fluctuations of sensory processing. For instance, during the preictal phase, migraineurs experience symptoms and signs of altered pain perception as well as other well-known premonitory CNS-symptoms. In the present study we measured EEG-activation to non-painful motor and sensorimotor tasks in the different phases of the migraine cycle by longitudinal...

article

The HUNT4 study: the validity of questionnaire-based diagnoses

Knut Hagen, Anders Nikolai Åsberg, Benjamin L. Uhlig, Erling Tronvik, more

The Journal of Headache and Pain > 2019 > 20 > 1 > 1-7

Background Questionnaire-based headache diagnoses should be validated against diagnoses made by the gold standard, which is personal interview by a headache expert. The diagnostic algorithm with the best diagnostic accuracy should be used when later analysing the data. Methods The Nord-Trøndelag Health Study (HUNT4) was performed between 2017 and 2019. Among HUNT4 participants, a total of 232 (19...

article

Pharmacokinetics and -dynamics of intramuscular and intranasal naloxone: an explorative study in healthy volunteers

Arne Kristian Skulberg, Ida Tylleskar, Turid Nilsen, Sissel Skarra, more

European Journal of Clinical Pharmacology > 2018 > 74 > 7 > 873-883

Purpose This study aimed to develop a model for pharmacodynamic and pharmacokinetic studies of naloxone antagonism under steady-state opioid agonism and to compare a high-concentration/low-volume intranasal naloxone formulation 8 mg/ml to intramuscular 0.8 mg. Methods Two-way crossover in 12 healthy volunteers receiving naloxone while receiving remifentanil by a target-controlled infusion for 102 min...

article

Do physical activity and body mass index modify the association between chronic musculoskeletal pain and insomnia? Longitudinal data from the HUNT study, Norway

Eivind S. Skarpsno, Tom I. L. Nilsen, Trond Sand, Knut Hagen, more

Journal of Sleep Research > 27 > 1 > 32 - 39

We investigated the prospective association between chronic musculoskeletal pain and risk of insomnia, and if leisure‐time physical activity and body mass index modify this association. The study comprised historical data on 11 909 women and 9938 men in the Norwegian HUNT study without sleep problems at baseline in 1995–97 and followed‐up for insomnia in 2006–08. Poisson regression was used to estimate...

article

The epidemiology of headache disorders: a face-to-face interview of participants in HUNT4

Knut Hagen, Anders Nikolai Åsberg, Benjamin L. Uhlig, Erling Tronvik, more

The Journal of Headache and Pain > 2018 > 19 > 1 > 1-6

Background The primary aim of this cross-sectional population-based study was to evaluate the 1-year prevalence of common headache disorders by a face-to-face interview. Methods The fourth wave of Nord-Trøndelag Health Survey (HUNT4) started in September 2017. The study was undertaken as part of a project mainly focusing on sleep disorders, where a total of 232 (19.3%) out of 1200 invited HUNT4...

article

Habituation of laser-evoked potentials by migraine phase: a blinded longitudinal study

Martin Uglem, Petter Moe Omland, Marit Stjern, Gøril Bruvik Gravdahl, more

The Journal of Headache and Pain > 2017 > 18 > 1 > 1-14

Background Migraineurs seem to have cyclic variations in cortical excitability in several neurophysiological modalities. Laser-evoked potentials (LEP) are of particular interest in migraine because LEP specifically targets pain pathways, and studies have reported different LEP-changes both between and during headaches. Our primary aim was to explore potential cyclic variations in LEP amplitude and...

article

Prolonged epileptiform EEG runs are associated with persistent seizures in juvenile myoclonic epilepsy

Vibeke Arntsen, Trond Sand, Marte R. Syvertsen, Eylert Brodtkorb

Epilepsy Research > 2017 > 134 > C > 26-32

In juvenile myoclonic epilepsy (JME), various EEG characteristics have been suggested as poor prognostic signs, but their significance is unclear. The aim of this study was to assess the influence of EEG variables on seizure and psychosocial outcome after a follow-up exceeding 20 years.396 EEG recordings were available for assessment in 40 patients (42 complete digital, 330 paper segments and 24 written...

article

Cognitive deficits associated with impaired awareness of hypoglycaemia in type 1 diabetes

Tor I. Hansen, Sandra E. Olsen, Elise C. D. Haferstrom, Trond Sand, more

Diabetologia > 2017 > 60 > 6 > 971-979

Aims/hypothesis The aim of this study was to compare cognitive function in adults with type 1 diabetes who have impaired awareness of hypoglycaemia with those who have normal awareness of hypoglycaemia. A putative association was sought between cognitive test scores and a history of severe hypoglycaemia. Methods A total of 68 adults with type 1 diabetes were included: 33 had impaired and 35 had...

article

The impact of sleep loss on the facilitation of seizures: A prospective case-crossover study

Christian Samsonsen, Trond Sand, Geir Bråthen, Grethe Helde, more

Epilepsy Research > 2016 > 127 > C > 260-266

The relationship between sleep and seizures is intricate. The aim of this study was to assess whether sleep loss is an independent seizure precipitant in a clinical setting.In this prospective, observational cross-over study, 179 consecutive hospital admissions for epileptic seizures were included. A semi-structured interview regarding several seizure precipitants was performed. The sleep pattern...

article

Mood and motor activity in euthymic bipolar disorder with sleep disturbance

Karoline Krane-Gartiser, Mette Kvisten Steinan, Knut Langsrud, Vegard Vestvik, more

Journal of Affective Disorders > 2016 > 202 > C > 23-31

The aims of this observational study of patients with euthymic bipolar disorder and sleep disturbance were to 1) compare characteristics related to mood and sleep between two groups with stable and unstable rest-activity cycles and 2) detect between-group differences in motor activity patterns.43 patients wore an actigraph for 6–8 days while reporting daily mood and sleep. Patients were defined as...

article

Visual evoked potentials in migraine: Is the “neurophysiological hallmark” concept still valid?

Petter M. Omland, Martin Uglem, Knut Hagen, Mattias Linde, more

Clinical Neurophysiology > 2016 > 127 > 1 > 810-816

Lack of habituation is considered a neurophysiological hallmark of migraine. However, the results of visual evoked potential (VEP) studies have been discrepant, possibly because of different stimulation parameters and lack of blinding. Hence, there is a need for independent confirmation of lack of VEP habituation in migraine. In this blinded study we applied 16′ checks to supplement our previous findings...

article

The effect of sleep restriction on laser evoked potentials, thermal sensory and pain thresholds and suprathreshold pain in healthy subjects

Siv Steinsmo Ødegård, Petter Moe Omland, Kristian Bernhard Nilsen, Marit Stjern, more

Clinical Neurophysiology > 2015 > 126 > 10 > 1979-1987

Sleep restriction seems to change our experience of pain and reduce laser evoked potential (LEP) amplitudes. However, although LEP-habituation abnormalities have been described in painful conditions with comorbid sleep impairment, no study has previously measured the effect of sleep restriction on LEP-habituation, pain thresholds, and suprathreshold pain.Sixteen males and seventeen females (aged 18–31years)...

article

Difficult morning awakening from rapid eye movement sleep and impaired cognitive function in delayed sleep phase disorder patients

Brandy Solheim, Knut Langsrud, Håvard Kallestad, Alexander Olsen, more

Sleep Medicine > 2014 > 15 > 10 > 1264-1268

Difficult awakening is a key symptom of delayed sleep phase disorder (DSPD), but no studies have quantified awakening thresholds in a sleep laboratory. This study assessed whether cognitive function was impaired after awakening and whether difficult awakening was associated with specific polysomnographic features such as slow wave sleep stage N3.Nine patients with DSPD and nine sex- and age-matched...

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INFONA - science communication portal

Search results for: Trond Sand

Contact‐free radar recordings of body movement can reflect ultradian dynamics of sleep

Validation of questionnaires for restless legs syndrome in the general population: the Trøndelag Health Study (HUNT)

Which combined nerve conduction study scores are best suited for polyneuropathy in diabetic patients?

Daily associations between sleep and pain in patients with chronic musculoskeletal pain

Validation of insomnia questionnaires in the general population: The Nord‐Trøndelag Health Study (HUNT)

Sleep restriction does not potentiate nocebo‐induced changes in pain and cortical potentials

Cognitive performance in DSWPD patients upon awakening from habitual sleep compared with forced conventional sleep

Fluctuations of sensorimotor processing in migraine: a controlled longitudinal study of beta event related desynchronization

The HUNT4 study: the validity of questionnaire-based diagnoses

Pharmacokinetics and -dynamics of intramuscular and intranasal naloxone: an explorative study in healthy volunteers

Do physical activity and body mass index modify the association between chronic musculoskeletal pain and insomnia? Longitudinal data from the HUNT study, Norway

The epidemiology of headache disorders: a face-to-face interview of participants in HUNT4

Habituation of laser-evoked potentials by migraine phase: a blinded longitudinal study

Prolonged epileptiform EEG runs are associated with persistent seizures in juvenile myoclonic epilepsy

Cognitive deficits associated with impaired awareness of hypoglycaemia in type 1 diabetes

The impact of sleep loss on the facilitation of seizures: A prospective case-crossover study

Mood and motor activity in euthymic bipolar disorder with sleep disturbance

Visual evoked potentials in migraine: Is the “neurophysiological hallmark” concept still valid?

The effect of sleep restriction on laser evoked potentials, thermal sensory and pain thresholds and suprathreshold pain in healthy subjects

Difficult morning awakening from rapid eye movement sleep and impaired cognitive function in delayed sleep phase disorder patients

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