Search results for: Patrick M. Catalano

Items from 1 to 20 out of 51 results

article

The roles of newborn anthropometrics in the association between maternal weight gain and childhood cardiovascular risks

Yuanying He, Lai Yuk Yuen, Ronald Ching Wan Ma, Patrick M. Catalano, more

Obesity > 30 > 12 > 2450 - 2458

Objective The aim was to study the association between newborn anthropometrics and childhood cardiovascular risks and whether newborn anthropometrics mediate the effect of maternal gestational weight gain (GWG) on childhood risks. Methods Data of 926 mother–child dyads from the Hyperglycemia and Adverse Pregnancy Outcomes study were analyzed. Newborn anthropometrics were treated as predictors and...

article

Association of weight status and carbohydrate intake with gestational weight gain

Makenzie L. Callahan, Camille R. Schneider‐Worthington, Samantha L. Martin, Barbara A. Gower, more

Clinical Obesity > 11 > 4 > n/a - n/a

Test the hypothesis that women with obesity have greater gestation weight gain (GWG) with a moderately higher, vs lower, carbohydrate (CHO) diet, independent of energy intake, whereas GWG for women of normal weight would not differ by CHO group. This was a secondary analysis of data collected from glucose tolerant women with normal weight (NW) or obesity in pregnancy. Women completed a three‐day food...

article

Augmented insulin secretory response in early pregnancy

Camille E. Powe, Larraine P. Huston Presley, Joseph J. Locascio, Patrick M. Catalano

Diabetologia > 2019 > 62 > 8 > 1445-1452

Aims/hypothesis This study aimed to examine changes in the insulin secretory response in early pregnancy, while accounting for changes in insulin sensitivity. Methods This is a secondary analysis of a previously conducted longitudinal physiological study. In 34 women, insulin secretory response (by IVGTT) and insulin sensitivity (by euglycaemic clamp) were assessed prior to pregnancy, in early pregnancy...

article

Maternal glucose levels during pregnancy and childhood adiposity in the Hyperglycemia and Adverse Pregnancy Outcome Follow-up Study

William L. Lowe, Lynn P. Lowe, Alan Kuang, Patrick M. Catalano, more

Diabetologia > 2019 > 62 > 4 > 598-610

Aims/hypothesis Maternal type 2 diabetes during pregnancy and gestational diabetes are associated with childhood adiposity; however, associations of lower maternal glucose levels during pregnancy with childhood adiposity, independent of maternal BMI, remain less clear. The objective was to examine associations of maternal glucose levels during pregnancy with childhood adiposity in the Hyperglycemia...

article

608: Does diet, physical activity or maternal adiposity affect the inflammatory profile in obese pregnancy?

McKenzie Wallace, Nitin Shivappa, Michael D. Wirth, James R. Hebert, more

American Journal of Obstetrics and Gynecology > 2018 > 218 > 1(S) > S362-S363

article

1012: Are changes in post-delivery glucose metabolism related to changes in cytokines, adipokines or lipids in women with gestational diabetes mellitus?

Thaddeus P. Waters, Judi Minium, Mary Haghiac, Larraine Presley, more

American Journal of Obstetrics and Gynecology > 2018 > 218 > 1(S) > S597-S598

article

Causal relationship between obesity-related traits and TLR4-driven responses at the maternal–fetal interface

Xiaohua Yang, Ming Li, Maricela Haghiac, Patrick M. Catalano, more

Diabetologia > 2016 > 59 > 11 > 2459-2466

Aims/hypothesis Obesity triggers complex inflammatory networks within the innate immune system. During pregnancy, the placenta amplifies the low-grade inflammation through activation of Toll-like receptor 4 (TLR4) signalling pathways. The purpose of this study was to investigate the impact of obesity on placental TLR4 expression and inflammatory signals. The secondary aim was to analyse the placental...

article

Maternal fat, but not lean, mass is increased among overweight/obese women with excess gestational weight gain

Erica K. Berggren, Sharon Groh-Wargo, Larraine Presley, Sylvie Hauguel-de Mouzon, more

American Journal of Obstetrics and Gynecology > 2016 > 214 > 6 > 745.e1-745.e5

Weight gain in pregnancy is an essential physiologic adaptation that supports growth and development of a fetus and is distributed among lean mass that includes total body water and fat mass gains. Although gestational weight gain provides a source of energy for the mother and fetus, excess gestational weight gain may underlie reported associations between parity and future metabolic disorders and...

article

570: What is the impact of fetal sex on maternal glucose metabolism?

Edward H. Springel, Erica K. Berggren, Larraine Huston-Presley, Patrick M. Catalano

American Journal of Obstetrics and Gynecology > 2016 > 214 > 1 Supplement > S307

article

838: Discrepant changes in carbohydrate metabolism from early to late postpartum in women with gestational diabetes (GDM)

Thaddeus P. Waters, Judi Minium, Mary Haghiac, Pamala Schnellinger, more

American Journal of Obstetrics and Gynecology > 2016 > 214 > 1 Supplement > S436

article

Identification of early transcriptome signatures in placenta exposed to insulin and obesity

Luciana Lassance, Maricela Haghiac, Patrick Leahy, Subhabrata Basu, more

American Journal of Obstetrics and Gynecology > 2015 > 212 > 5 > 647.e1-647.e11

The purpose of this study was to investigate the effects of insulin on human placental transcriptome and biological processes in first-trimester pregnancy.Maternal plasma and placenta villous tissue were obtained at the time of voluntary termination of pregnancy (7-12 weeks) from 17 lean (body mass index, 20.9 ± 1.5 kg/m ² ) and 18 obese (body mass index, 33.5 ± 2.6 kg/m ² ) women...

article

Are the metabolic changes of pregnancy reversible in the first year postpartum?

Erica K. Berggren, Larraine Presley, Saeid B. Amini, Sylvie Hauguel-de Mouzon, more

Diabetologia > 2015 > 58 > 7 > 1561-1568

Aims/hypothesis Maternal metabolic alterations are essential to achieve healthy pregnancy outcomes, but increasing maternal parity may be associated with long-term metabolic dysfunction risk. As existing data are limited by study design, our aim was to employ robust metabolic measures to determine whether or not physiological pregnancy alterations in maternal metabolic function persist at 1 year postpartum...

article

A retrospective cohort study of factors relating to the longitudinal change in birth weight

Kelly S. Gibson, Thaddeus P. Waters, Douglas D. Gunzler, Patrick M. Catalano

BMC Pregnancy and Childbirth > 2015 > 15 > 1 > 1-7

Background Recent reports have shown a decrease in birth weight, a change from prior steady increases. Therefore we sought to describe the demographic and anthropometric changes in singleton term fetal growth. Methods This was a retrospective cohort analysis of term singleton deliveries (37–42 weeks) from January 1, 1995 to January 1, 2010 at a single tertiary obstetric unit. We included all 43,217...

article

Sex-specific effects of maternal anthropometrics on body composition at birth

Perrie O’Tierney-Ginn, Larraine Presley, Judi Minium, Sylvie Hauguel deMouzon, more

American Journal of Obstetrics and Gynecology > 2014 > 211 > 3 > 292.e1-292.e9

The purpose of this study was to assess whether maternal factors that are associated with fetal lean and fat mass differ between sexes.Secondary analysis of a prospective cohort that delivered by scheduled cesarean section from 2004-2013. Maternal blood was collected before surgery for metabolic parameters. Placental weight and neonatal anthropometrics were measured within 48 hours. Anthropometric...

article

Inadequate weight gain in overweight and obese pregnant women: what is the effect on fetal growth?

Patrick M. Catalano, Lisa Mele, Mark B. Landon, Susan M. Ramin, more

American Journal of Obstetrics and Gynecology > 2014 > 211 > 2 > 137.e1-137.e7

We sought to evaluate inadequate gestational weight gain and fetal growth among overweight and obese women.We conducted an analysis of prospective singleton term pregnancies in which 1053 overweight and obese women gained >5 kg (14.4 ± 6.2 kg) or 188 who either lost or gained ≤5 kg (1.1 ± 4.4 kg). Birthweight, fat mass, and lean mass were assessed using anthropometry. Small for gestational age...

article

Does the dawn phenomenon have clinical relevance in normal pregnancy?

Alicia Mandujano, Alicia Thomas, Larraine Huston Presley, Saeid B. Amini, more

American Journal of Obstetrics and Gynecology > 2013 > 209 > 2 > 116.e1-116.e5

The dawn phenomenon is a transient rise in blood glucose between 4 and 6 am that is attributed to the pulsatile release of pituitary growth hormone (GH). In pregnancy, GH is suppressed by placental GH. Hence, we hypothesize that there is no evidence for the dawn phenomenon in late pregnancy in healthy women.Twenty glucose-tolerant women with singleton gestations between 28 weeks and 36 weeks 6 days’...

article

A multifactorial relationship exists between total circulating cell‐free DNA levels and maternal BMI

Neeta L. Vora, Kirby L. Johnson, Subhabrata Basu, Patrick M. Catalano, more

Prenatal Diagnosis > 32 > 9 > 912 - 914

article

Timing of Indicated Late Preterm and Early-Term Birth in Chronic Medical Complications: Diabetes

Patrick M. Catalano, David A. Sacks

Seminars in Perinatology > 2011 > 35 > 5 > 297-301

The number of pregnant women who have type 2 diabetes and the number found to have gestational diabetes are progressively increasing. In the future, as many as 20% of pregnant women may be diagnosed with diabetes. Although there is consensus regarding many issues in the treatment of pregnant women with diabetes, there are few evidenced-based studies upon which to base the timing of delivery. There...

article

Is it time to revisit the Pedersen hypothesis in the face of the obesity epidemic?

Patrick M. Catalano, Sylvie Hauguel-De Mouzon

American Journal of Obstetrics and Gynecology > 2011 > 204 > 6 > 479-487

The Pedersen hypothesis was formulated more than 50 years ago. Jorgen Pedersen primarily cared for women with type 1 diabetes. He suggested that fetal overgrowth was related to increased transplacental transfer of glucose, stimulating the release of insulin by the fetal beta cell and subsequent macrosomia. Optimal maternal glucose control decreased perinatal mortality and morbidity. However, over...

article

Differential regulation of genes for fetoplacental lipid pathways in pregnancy with gestational and type 1 diabetes mellitus

Tatiana Radaelli, Jacques Lepercq, Ali Varastehpour, Subhabrata Basu, more

American Journal of Obstetrics and Gynecology > 2009 > 201 > 2 > 209.e1-209.e10

Changes in metabolic homeostasis in pregnant diabetic women are potential determinants of increased adiposity of the fetus. The aim of this study was to characterize diabetes mellitus-induced changes in genes for fetoplacental energy metabolism in relation to fetal adiposity.Placentas of women with type 1 diabetes mellitus, gestational diabetes mellitus (GDM), or no complications were analyzed by...

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INFONA - science communication portal

Search results for: Patrick M. Catalano

The roles of newborn anthropometrics in the association between maternal weight gain and childhood cardiovascular risks

Association of weight status and carbohydrate intake with gestational weight gain

Augmented insulin secretory response in early pregnancy

Maternal glucose levels during pregnancy and childhood adiposity in the Hyperglycemia and Adverse Pregnancy Outcome Follow-up Study

608: Does diet, physical activity or maternal adiposity affect the inflammatory profile in obese pregnancy?

1012: Are changes in post-delivery glucose metabolism related to changes in cytokines, adipokines or lipids in women with gestational diabetes mellitus?

Causal relationship between obesity-related traits and TLR4-driven responses at the maternal–fetal interface

Maternal fat, but not lean, mass is increased among overweight/obese women with excess gestational weight gain

570: What is the impact of fetal sex on maternal glucose metabolism?

838: Discrepant changes in carbohydrate metabolism from early to late postpartum in women with gestational diabetes (GDM)

Identification of early transcriptome signatures in placenta exposed to insulin and obesity

Are the metabolic changes of pregnancy reversible in the first year postpartum?

A retrospective cohort study of factors relating to the longitudinal change in birth weight

Sex-specific effects of maternal anthropometrics on body composition at birth

Inadequate weight gain in overweight and obese pregnant women: what is the effect on fetal growth?

Does the dawn phenomenon have clinical relevance in normal pregnancy?

A multifactorial relationship exists between total circulating cell‐free DNA levels and maternal BMI

Timing of Indicated Late Preterm and Early-Term Birth in Chronic Medical Complications: Diabetes

Is it time to revisit the Pedersen hypothesis in the face of the obesity epidemic?

Differential regulation of genes for fetoplacental lipid pathways in pregnancy with gestational and type 1 diabetes mellitus

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