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Objective
Decreased insulin sensitivity and impairment of β‐cell function predate and predict development of type 2 diabetes mellitus. Time‐restricted eating (TRE) might have a benefit for these parameters. The objective of this pilot study was to investigate this possibility.
Methods
Secondary analysis of a randomized controlled trial comparing 12 weeks of TRE (8‐hour eating window) to unrestricted...
Objective
Time‐restricted eating (TRE) restores circadian rhythms in mice, but the evidence to support this in humans is limited. The objective of this study was to investigate the effects of TRE on 24‐hour profiles of plasma metabolites, glucoregulatory hormones, and the subcutaneous adipose tissue (SAT) transcriptome in humans.
Methods
Men (n = 15, age = 63 [4] years, BMI 30.5 [2.4] kg/m2) were...
Objective
This study explored the impact of time‐restricted eating (TRE) versus standard dietary advice (SDA) on bone health.
Methods
Adults with ≥1 component of metabolic syndrome were randomized to TRE (ad libitum eating within 12 hours) or SDA (food pyramid brochure). Bone turnover markers and bone mineral content/density by dual energy x‐ray absorptiometry were assessed at baseline and 6‐month...
Objective
In contrast to intentionally restricting energy intake, restricting the eating window may be an option for treating obesity. By comparing time‐restricted eating (TRE) with an unrestricted (non‐TRE) control, it was hypothesized that TRE facilitates weight loss, alters body composition, and improves metabolic measures.
Methods
Participants (17 women and 3 men; mean [SD]: 45.5 [12.1] years;...
Mammalian circadian rhythms are entrained by photic stimuli that are relayed by retinal projections to the core of the suprachiasmatic nucleus (SCN). Neuronal activation, as demonstrated by expression of the immediate early gene c‐fos, leads to transcription of the core clock gene per1. The duper mutation in hamsters shortens circadian period and amplifies light‐induced phase shifts. We performed...
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