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Solvent environments significantly affect the enzymatic function of Escherichia coli dihydrofolate reductase: Comparison of wild-type protein and active-site mutant D27E
Okazaki Institute for Integrative Bioscience and Institute for Molecular Science, National Institutes of Natural Sciences, Okazaki, Aichi 444-8787, Japan
Department of Functional Molecular Science, School of Physical Sciences, the Graduate University for Advanced Studies (Sokendai), Okazaki, Aichi 444-8787, Japan