The Infona portal uses cookies, i.e. strings of text saved by a browser on the user's device. The portal can access those files and use them to remember the user's data, such as their chosen settings (screen view, interface language, etc.), or their login data. By using the Infona portal the user accepts automatic saving and using this information for portal operation purposes. More information on the subject can be found in the Privacy Policy and Terms of Service. By closing this window the user confirms that they have read the information on cookie usage, and they accept the privacy policy and the way cookies are used by the portal. You can change the cookie settings in your browser.
Piezoelectric single crystals (piezocrystals) of lead magnesium niobate-lead titante (PMN-PT) and lead zinc niobate-lead titanate (PZN-PT) have extremely large electromechanical coupling coefficients and exhibit strains of over one percent. The technical significance of these properties to devices is enormous and includes a doubling of bandwidth, decreased package size, and increased resolution. The...
Cardiovascular disease, including atherosclerosis and critical limb ischemia, affects millions of people worldwide. There is a clinical need to base treatment decisions on quantitative analysis of the plaque composition. However, no reliable clinical methods to quantify the mechanical properties of plaque components and detect plaque vulnerability currently exist, particularly for coronary disease...
Modification of dissolved gas content by nucleation of acoustic droplet vaporization (ADV) has been proposed for several therapeutic applications. Reducing dissolved oxygen could inhibit reactive oxygen species production during reperfusion of ischemic tissue, such as during coronary interventions to rescue myocardium. Localization of the effect may be achieved using intravascular ultrasound (IVUS),...
Flow cytometer plays a key role in cell sorting and analysis. For a higher detection precision, sheath flow is adopted to avoid the turbulent or vortex effect when the cell flowing through a capillary tube during the cell counting in many commercial cytometers. This method works well when the low flow velocity is relatively low. However, in order to have a higher analysis efficiency for clinical laboratories,...
One of the primary motivations for using ultrasound reflectometry for fingerprint imaging is the promise of increased spoof resistance over conventional optical or capacitive sensing approaches due to the ability for ultrasound to determine the elastic impedance of the imaged material. A fake 3D printed plastic finger can therefore be easily distinguished from a real finger. However, ultrasonic sensors...
Piezoelectric ultrasonic motors (PUMs) are based on the concept of driving the runner by a mechanical vibration excited on the stator via the converse piezoelectric effect. They exhibit merits of small size, simple structure, quick response, high accuracy and resolution, self-locking when power off and a lack of electromagnetic radiation. The linear PUMs become the research focus in recent years as...
Previous study has demonstrated that pulsed HIFU with tens of microseconds pulse duration (PD) and 10kHz PRF is effective for cavitation generation. Meanwhile, with the assistance of PFC nanodroplets, cavitation can be further enhanced. Despite of higher efficiency, we also need cavitation to be precisely controlled and confined for sake of therapeutic safety, especially during the implementation...
Rodents are used extensively in research to study disease and evaluate drugs. Preclinical imaging systems allow for non-invasive assessments of animals. High frequency ultrasound systems have emerged over the last 15 years as valuable tools for evaluating numerous diseases and organs. When compared against other anatomical imaging systems, such as MRI and CT, ultrasound is the most cost effective,...
Multi-frequency transducers may have a number of emerging applications including multi-scale imaging, superharmonc contrast imaging and imaging-therapy applications. For imaging-therapy applications low-frequencies are typically needed for therapeutic heating or contrast agent destruction, while higher-frequencies are required for high-resolution imaging. However, development of these multi-frequency...
Super-resolution techniques that localise isolated bubble signals first require detection algorithms to separate the bubble and tissue responses. This work explores the available bubble detection techniques for super-resolution of tumour microvasculature. Pulse inversion (PI), differential imaging (DI) and singular value decomposition (SVD) filtering were compared in terms of the localisation accuracy,...
We present an ultrasonic transit-time gas flow meter (UFM) that features a 40-kHz 8×8 2D-phased array for transmitting ultrasonic sound waves up- and downstream to two single element receivers. This allows us to electronically compensate for the well-known parasitic sound drift effect, resulting in larger measurement range and better signal-to-noise-ratio (SNR). The UFM fabricated consists of a pipe...
The aim of this study is to investigate how the intracellular ROS responds to different degrees of sonoporation. Using a customized platform for 1.5-MHz ultrasound exposure (13.33-μs duration and 0.70-MPa peak negative pressure) and observing the dynamics of sonoporation and intracellular ROS at the single-cell level, we quantified the exogenous molecular uptake and intracellular ROS indicator to...
Intravascular ultrasound (IVUS) is a well-established diagnostic method that has been applied frequently for providing high-resolution images of vessel wall and atherosclerotic plaques. Side looking transducer has been employed in a catheter for delineating the structure of vessel wall and lesions. However, it is difficult to get the flow distribution in the vessel by side looking transducer as the...
High-intensity focused ultrasound (HIFU) have been an attractive research topic for some time now. HIFU studies have started with single-element transducers, but using arrays provide the opportunity to scan the focal point electronically. Modular and scalable driving systems that can be used with custom-made transducer elements to drive these arrays are needed and at the present time there are few...
In the present study, chirp coded pulses are investigated with respect to high frequency imaging. These pulses were used drive broadband polymer transducers assembled from an adhesive-free layer-be-layer deposition method. The image quality obtained from using a long chirp coded pulse was compared with images generated from shorter pulses. This includes the Ricker wavelet and the square pulse most...
The ability to measure perfusion rates of tissues in a non-invasive and label-free way could enable powerful diagnostic applications to peripheral vascular disease, ischemia, tumor hypoxia, ulcer characterization, and general tissue health. However, current medical techniques of measuring perfusion rates, which include contrast-enhanced ultrasound imaging, perfusion MR imaging require contrast agents...
Arbitrary excitation waveforms are desirable in HIFU array systems. In trans-skull therapy this is necessary to compensate for phase aberrations and achieve even heating of the skull. To facilitate this, wave form generators and large, costly class A RF amplifiers are used. High element counts are commonplace and so the portability of these systems is greatly reduced. We propose using switched mode...
Over the last decade, clinical studies show a strong interest for real-time 3D imaging. This calls for ultrasound probes with high-element-count 2D matrix transducer array, interfaced to an imaging system using an in-probe Application Specific Integrated Circuit (ASIC) that takes care of element selection, signal amplification, sub-array beamforming, etc. Since the ASIC is based on silicon and is...
Atherosclerosis in the carotid artery (CA) elevates the risk for cerebral events. Strain imaging has demonstrated to be a technique capable of identifying plaque composition. For strain imaging of carotid cross-sections, compound techniques have been developed to solve the poor strain estimation quality perpendicular to the ultrasound beam direction. This study assesses the performance of radial and...
Investigating biomechanical properties of the cornea can have many clinical applications, including the diagnosis of keratoconus and post-refractive keratectasia. However, ascertaining the biomechanical properties of cornea remains a challenge because of the low resolution of currently available modalities cannot provide a point-to-point stiffness mapping of cornea. In this study, we reported a high-resolution...
Set the date range to filter the displayed results. You can set a starting date, ending date or both. You can enter the dates manually or choose them from the calendar.