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In this paper, we try to establish newly technique that the components of the biological clock are reconstituted into the liposome. In other words, we try to produce a nano size clock, capsulated into the liposome, made by protein molecules. The circadian clock is a basic cellular system found in almost all organisms. This clock generates self-sustained oscillations under constant conditions with...
In this paper, we try to establish newly technique that the components of the biological clock are reconstituted into the liposome. In other words, we try to produce a nano size clock, capsulated into the liposome, made by protein molecules. The circadian clock is a basic cellular system found in almost all organisms. This clock generates self-sustained oscillations under constant conditions with...
In biological and medical sciences, optical microscopes are widely used. By using the microscope, we can observe cellular dynamics including intracellular ions and molecules tagged with fluorescent dyes at a high magnification. However, a freely motile cell easily escapes from a field of view and a focal plane of the typical microscope. Therefore, we propose a novel auto-focusing (AF) algorithm and...
In biological and medical sciences, optical microscopes are widely used. By using the microscope, we can observe cellular dynamics including intracellular ions and molecules tagged with fluorescent dyes at a high magnification. However, a freely motile cell easily escapes from a field of view and a focal plane of the typical microscope. Therefore, we propose a novel auto-focusing (AF) algorithm and...
In this paper, we proposed cell investigation tool for measurement of physiological conditions of single cell. We developed a novel temperature measurement method using temperature dependence of the quantum dot. The cell investigation tool encapsulates the quantum dot and adheres to the cell membrane. These tools can be manipulated in a solution by optical tweezers. We proposed image processing of...
In this paper, we proposed cell investigation tool for measurement of physiological conditions of single cell. We developed a novel temperature measurement method using temperature dependence of the quantum dot. The cell investigation tool encapsulates the quantum dot and adheres to the cell membrane. These tools can be manipulated in a solution by optical tweezers. We proposed image processing of...
Microrobotics is a field of high interest in the recent past. Commonly used imaging modalities in this field include optical microscopes and scanning electron microscopes (SEM). Due to the scanning principle of the SEMs, objects in motion may not be represented in the SEM images the same way as they really are. Movement leads to movement artifacts. This effect strongly limits the possibilities for...
Microrobotics is a field of high interest in the recent past. Commonly used imaging modalities in this field include optical microscopes and scanning electron microscopes (SEM). Due to the scanning principle of the SEMs, objects in motion may not be represented in the SEM images the same way as they really are. Movement leads to movement artifacts. This effect strongly limits the possibilities for...
In the field of bioscience, such as regeneration medicine and cloning, the manipulation and analysis for cells are performed by many researchers. However, manual operation for such micro objects is not feasible and practical for beginner operators. As for the problem, we have developed a two-fingered microhand supporting manual operation. Using the microhand, we can manipulate cells i.e., grab, rotate,...
In the field of bioscience, such as regeneration medicine and cloning, the manipulation and analysis for cells are performed by many researchers. However, manual operation for such micro objects is not feasible and practical for beginner operators. As for the problem, we have developed a two-fingered microhand supporting manual operation. Using the microhand, we can manipulate cells i.e., grab, rotate,...
Motivated by the need for torque sensing in the µNm range for experiments with insect-sized flapping-wing robots, we present the design, fabrication and testing of a custom single-axis torque sensor. The micorobots in question are too large for MEMS force/torque sensors used for smaller live insects such as fruit flies, but too small to produce torques within the dynamic range of commercially available...
Motivated by the need for torque sensing in the µNm range for experiments with insect-sized flapping-wing robots, we present the design, fabrication and testing of a custom single-axis torque sensor. The micorobots in question are too large for MEMS force/torque sensors used for smaller live insects such as fruit flies, but too small to produce torques within the dynamic range of commercially available...
Nano force sensors based on passive diamagnetic levitation with a macroscopic seismic mass are a possible alternative to classical Atomic Force Microscopes when the force bandwidth to be measured is limited to a few Hertz. When an external unknown force is applied to the levitating seismic mass, this one acts as a transducer that converts this unknown input into a displacement that is the measured...
Nano force sensors based on passive diamagnetic levitation with a macroscopic seismic mass are a possible alternative to classical Atomic Force Microscopes when the force bandwidth to be measured is limited to a few Hertz. When an external unknown force is applied to the levitating seismic mass, this one acts as a transducer that converts this unknown input into a displacement that is the measured...
This paper reports on the description of a new high force-resolution microgripper with large jaw displacement, electrostatically actuated by a comb-drive and instrumented with an integrated differential capacitive displacement sensor. This microgripper has been non-intuitively designed using a multi-objective optimization method, to reach the best compromise between chosen performance criteria. It...
This paper reports on the description of a new high force-resolution microgripper with large jaw displacement, electrostatically actuated by a comb-drive and instrumented with an integrated differential capacitive displacement sensor. This microgripper has been non-intuitively designed using a multi-objective optimization method, to reach the best compromise between chosen performance criteria. It...
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