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Here we have developed a novel large-field high-resolution two-photon digital scanned light-sheet microscopy (2P3A-DSLM) based on ultrafast axial scanning of illumination focal spot with a tunable acoustic gradient (TAG) index device. This new technique provides a sub-micron axial resolution with a large field of view in deep tissues. In vivo imaging with 2P3A-DSLM resolves functional maturation of...
Phase change materials such as chalcogenides and complex oxides possess electronic structures that are widely tunable via external stimuli. Under the right triggers, these can be volatile (threshold switches) or non-volatile (memory). I will present an overview of correlated oxide systems where one can create sub-wavelength dielectric environments on-demand. The role of materials synthesis and their...
We discuss our efforts in developing nanophotonic structures for the control of thermal radiation. These structures enable new spectral, angular, and reciprocal properties of thermal radiation, and new applications such as radiative cooling.
Graphene is promising material for high quality nano-resonators with low mass and high quality factor [1,2]. These properties make graphene resonators suitable candidates for studying a mechanical system in the quantum regime and to explore effects such as Casimir forces [3]. However, the readout of a mechanical quantum state requires a non-invasive measurement method. To this end, one approach is...
This tutorial will discuss appropriate techniques for reaching the ultimate communication capacity limit including discussion of the limit itself along with technological advances in multilevel signalling, digital signal processing, optical nonlinearity compensation, and spatial-mode-division multiplexing.
Dielectric multilayered structures are introduced here as building blocks of disposable chips for sensing applications. Some experimental configurations are illustrated wherein flat or patterned multilayers are employed for sensing in either label-free, spectroscopic or fluorescence operational modes. In particular, the possibility to enhance and control the emission from fluorescence markers on the...
Recently, it has been demonstrated that infrared light can activate (e.g., optical pacing) or inhibit action potentials without the need of exogenous agents. Here, we will describe some of the latest developments and applications.
In this tutorial I will describe key ideas, results, and challenges in using high harmonic generation to track attosecond charge flow in atoms, molecules, and dielectrics, including recent applications to time-resolving chiral response in molecules, and to the generation of tailored attosecond pulses.
Cilia are organelles that generate microfluidic flows in the lungs, central nervous system, and Fallopian tubes. Quantitative flow diagnostic remain immature. I will present a comprehensive optical imaging-based approach for quantifying cilia flow physiology.
Fluorescent nanodiamonds that host ultra bright emitters are highly attractive for biomedical applications. We present several approaches to enhance brightness of the nanodiamonds via bio-compatible coating as well as use of new near infra-red emitters for biolabeling and biosensing.
Coupling terahertz pulses to sharp metal tips has recently enabled imaging of ultrafast dynamics in materials on the nanoscale. An overview of some of the techniques, in particular terahertz scanning tunneling microscopy, is presented.
We discuss the methods of fabricating complex three-dimensional nano-structures in a large scale, in particular, laser drawing method based on two-photon photo-reduction and self-growing of metallic fractal structures with plasmonic reduction.
Photons are natural carriers of quantum information over long distances. Matter systems have good storage capabilities and processing qubits. However, it is challenging to integrate all these capabilities into one system. The nitrogen-vacancy (NV) defect center in diamond does show significant potential for realizing solid-state quantum networks. The NV center provides a hybrid spin system in which...
EUV lithography remains the preferred option for 7-nm node semiconductor device manufacturing. Successful insertion of this technology into manufacturing, however, will also depend on the development and deployment of new EUV actinic metrologies. Here we describe the metrology needs and status of such systems and the critical components they require.
We characterize a passively carrier envelope phase-stabilized Er:fiber laser frequency comb at 1550 nm. Phase noise of single comb lines over nearly an optical octave is measured via a delayed self-heterodyne beat of a cw clean-up laser. Repetition-rate stabilization achieves a RF-reference limited line-width. A lock to a low-noise optical reference shows Hz level out-of-loop line-widths. The measured...
Advanced LIGO has directly observed gravitational waves during its first science run. In this talk I will discuss the astrophysical reach of LIGO interferometers during the run and prospects for the future.
The recent detection of gravitational waves was made possible by the finest laser interferometers ever built. I will describe Advanced LIGO's optics, isolation, and control systems and discuss how the recent upgrades have changed our ability to “listen” to the universe.
We investigate the spatial eigenmodes of a Gaussian-beam-pumped traveling-wave phase-sensitive optical parametric amplifier, demonstrating a markedly efficient gain response for the signal's fundamental eigenmode with optimized axial waist location.
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