Breast Cancer Research is the highest ranking breast cancer-specific title in the top quartile of oncology journals worldwide. Primarily publishing original research, literature reviews, and invited editorials, the journal also publishes preclinical, translational and clinical studies with a biological basis, including Phase I and Phase II trials. Breast Cancer Research publishes content on the following topics: Clinical Interventions; Cellular or Molecular Pathogenesis; Pathology; Genomics and High-throughput Technologies; Mammary Gland Biology; Imaging; Screening & Prevention; and Epidemiology.
Breast Cancer Research
Description
Identifiers
e-ISSN | 1465-542X |
Publisher
BioMed Central
Additional information
Data set: Springer
Articles
Breast Cancer Research > 2019 > 21 > 1 > 1-12
Background To obtain a deep understanding of the mechanism by which breast cancer develops, the genes involved in tumorigenesis should be analyzed in vivo. Mouse mammary gland can regenerate completely from a mammary stem cell (MaSC), which enables us to analyze the effect of gene expression and repression on tumorigenesis in mammary gland regenerated from genetically manipulated MaSCs. Although lentiviral...
Breast Cancer Research > 2019 > 21 > 1 > 1-10
Introduction Ductal carcinoma in situ (DCIS) is a non-obligate precursor of invasive ductal breast cancer, and approximately 20% of screen-detected tumours are pure DCIS. Most risk factors for breast cancer have similar associations with DCIS and IDC; however, there is limited data on the prevalence of the known high and moderate penetrance breast cancer predisposition genes in DCIS and which women...
Breast Cancer Research > 2019 > 21 > 1 > 1-16
Background Acquirement of resistance is always associated with a highly aggressive phenotype of tumor cells. Recent studies have revealed that Annexin A2 (Anxa2) is a key protein that links drug resistance and cancer metastasis. A high level of Anxa2 in cancer tissues is correlated to a highly aggressive phenotype. Increased Anxa2 expression appears to be specific in many drug-resistant cancer cells...