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A novel optical biosensor based on gold nanorods (GNRs) was designed and fabricated for simple, sensitive and competitive detection of aflatoxin B1 (AFB1). Free AFB1 target interacted with capture antibodies, competing with AFB1-BSA (Bovine serum albumin) conjugate modified GNRs. Aggregation of GNRs was observed if the amount of AFB1 target was not enough. As a result, an associated decrease in the...
The fast and sensitive detections of chemicals adsorption onto solid substrates are of importance to many fields. Ordered arrays of gold nanoparticles with strong surface plasmon resonances allow directly visualized detection of molecular scale adsorptions of mercury vapor on solid substrates. The adsorbed species change local dielectric constants surrounding plasmonic nanoparticles, leading to shifts...
This study presents combination of advantages in MEMS technology and molecular methods for detection of methicillin resistant gene, mecA, in Staphylococcus aureus. A disposable MEMS DNA biosensor was designed and fabricated for optical and electrochemical detections. Adsorption of DNA on gold electrode was examined theoretically and experimentally. In theoretical studies, Lennard Jones potential energies...
Capacitive humidity sensors were fabricated using countersunk interdigitated electrodes coated with amorphous nanostructured TiO2, SiO2, and Al2O3 thin films grown by glancing angle deposition. The capacitive response and response times for each sensor were measured. The sensor utilizing TiO2 exhibited the largest change in capacitance, increasing exponentially from ~ 1 nF to ~ 1muF for an increase...
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