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Intrinsic resistance to antibiotics is a serious therapeutic problem in the case of many bacterial species. The Gram‐positive human pathogen Listeria monocytogenes is intrinsically resistant to broad spectrum cephalosporin antibiotics, which are commonly used in therapy of bacterial infections. Besides three penicillin‐binding proteins the intrinsic cephalosporin resistome of L. monocytogenes includes...
Listeria monocytogenes, a food-borne intracellular animal and human pathogen, interacts with infected host cells both prior to entry and during the intracellular phase of infection. This review is focused on the role of secreted proteins including listeriolysin O and two distinct phospholipases C, in modulating the signal transduction of infected cells.
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