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Research on dietary modulation of inflammatory bowel disease is in its infancy. Dietary heme, mimicking red meat, is cytotoxic to colonic epithelium and thus may aggravate colitis. Alternatively, heme-induced colonic stress might also result in potential protective heat-shock proteins (HSPs). Therefore, we investigated the effect of dietary heme on trinitrobenzene sulfonic acid (TNBS)–induced colitis...
Patients on total parenteral nutrition depend on the composition of the nutritional formulation for maintenance of their oxidant–antioxidant balance. The present observational study was conducted to evaluate a substantial part of our patient population for evidence of oxidative stress.Venous blood samples were obtained from 41 patients on home parenteral nutrition (HPN) and 41 healthy controls. Glutathione...
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