Search results for: Monika Haack

Items from 1 to 19 out of 19 results

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Chronic sleep restriction differentially affects implicit biases toward food among men and women: preliminary evidence

Anna Alkozei, William D. S. Killgore, Ryan Smith, Natalie S. Dailey, more

Journal of Sleep Research > 27 > 4 > n/a - n/a

Chronic sleep restriction and obesity are two major public health concerns. This study investigated how chronic sleep restriction changes implicit attitudes towards low‐ and high‐calorie foods. In a randomized, counterbalanced cross‐over design, 17 participants (eight females, nine males) underwent two laboratory testing sessions where they were either sleep‐restricted for 3 weeks (i.e. underwent...

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Repeating patterns of sleep restriction and recovery: Do we get used to it?

Norah S. Simpson, Moussa Diolombi, Jennifer Scott-Sutherland, Huan Yang, more

Brain, Behavior, and Immunity > 2016 > 58 > C > 142-151

Despite its prevalence in modern society, little is known about the long-term impact of restricting sleep during the week and ‘catching up’ on weekends. This common sleep pattern was experimentally modeled with three weeks of 5 nights of sleep restricted to 4h followed by two nights of 8-h recovery sleep. In an intra-individual design, 14 healthy adults completed both the sleep restriction and an...

article

Sleep characteristics as predictor variables of stress systems markers in insomnia disorder

Samantha Floam, Norah Simpson, Emese Nemeth, Jennifer Scott‐Sutherland, more

Journal of Sleep Research > 24 > 3 > 296 - 304

This study investigates the extent to which sleep characteristics serve as predictor variables for inflammatory, hypothalamic–pituitary–adrenal and autonomic systems markers. Twenty‐nine participants with a diagnosis of insomnia disorder based on the Diagnostic Statistical Manual of Mental Disorders, Fifth Edition (age 25.3 ± 1.6 years, insomnia duration 6.6 ± 0.8 years) and 19 healthy control sleepers...

article

Increasing sleep duration to lower beat‐to‐beat blood pressure: a pilot study

Monika Haack, Jorge Serrador, Daniel Cohen, Norah Simpson, more

Journal of Sleep Research > 22 > 3 > 295 - 304

Strong evidence has accumulated over the last several years, showing that low sleep quantity and/or quality plays an important role in the elevation of blood pressure. We hypothesized that increasing sleep duration serves as an effective behavioral strategy to reduce blood pressure in prehypertension or type 1 hypertension. Twenty‐two participants with prehypertension or stage 1 hypertension, and...

article

Sleep loss and inflammation

Janet M. Mullington, Norah S. Simpson, Hans K. Meier-Ewert, Monika Haack

Best Practice & Research Clinical Endocrinology & Metabolism > 2010 > 24 > 5 > 775-784

Controlled, experimental studies on the effects of acute sleep loss in humans have shown that mediators of inflammation are altered by sleep loss. Elevations in these mediators have been found to occur in healthy, rigorously screened individuals undergoing experimental vigils of more than 24h, and have also been seen in response to various durations of sleep restricted to between 25 and 50% of a normal...

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Activation of the prostaglandin system in response to sleep loss in healthy humans: Potential mediator of increased spontaneous pain

Monika Haack, Erin Lee, Daniel A. Cohen, Janet M. Mullington

Pain > 2009 > 145 > 1-2 > 136-141

Insufficient duration of sleep is a highly prevalent behavioral pattern in society that has been shown to cause an increase in spontaneous pain and sensitivity to noxious stimuli. Prostaglandins (PGs), in particular PGE2, are key mediators of inflammation and pain, and we investigated whether PGE2 is a potential mediator in sleep-loss-induced changes in nociceptive processing. Twenty-four participants...

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Cardiovascular, Inflammatory, and Metabolic Consequences of Sleep Deprivation

Janet M. Mullington, Monika Haack, Maria Toth, Jorge M. Serrador, more

Progress in Cardiovascular Diseases > 2009 > 51 > 4 > 294-302

That insufficient sleep is associated with poor attention and performance deficits is becoming widely recognized. Fewer people are aware that chronic sleep complaints in epidemiologic studies have also been associated with an increase in overall mortality and morbidity. This article summarizes findings of known effects of insufficient sleep on cardiovascular risk factors including blood pressure,...

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Shorter habitual sleep duration is associated with higher increase in subjective estimation of pain in response to a total sleep deprivation (TSD) challenge

Monika Haack, Janet M. Mullington

Brain Behavior and Immunity > 2006 > 20 > 3 Supplement > 29-30

article

Sustained sleep restriction reduces emotional and physical well-being

Monika Haack, Janet M. Mullington

Pain > 2005 > 119 > 1-3 > 56-64

Background: Chronic insufficient sleep is a common finding in many pain-related and other medical diseases and is frequently experienced in the general population. Prolonged curtailment of nocturnal sleep has been studied for its adverse effect on cognitive functioning and subjective tiredness, but relatively little is known about its effect on mood and physical symptoms. Objective: In order to test...

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#54 Subjective estimations of pain increase in both total sleep deprivation and partial sleep deprivation

Monika Haack, Janet M. Mullington

Brain Behavior and Immunity > 2005 > 19 > 4 Supplement > e28

article

Early prediction of changes in weight during six weeks of treatment with antidepressants

Hubertus Himmerich, Andreas Schuld, Monika Haack, Christian Kaufmann, more

Journal of Psychiatric Research > 2004 > 38 > 5 > 485-489

Weight gain is a frequent and important side effect of psychotropic treatment. We sought to determine weight change predictors during treatment with antidepressant drugs. In 24 patients weight, plasma levels of leptin, tumor necrosis factor-α (TNF-α) and soluble TNF receptors were determined longitudinally and a multiple linear regression analysis was used to predict weight change from baseline to...

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Diurnal and sleep-wake dependent variations of soluble TNF- and IL-2 receptors in healthy volunteers

Monika Haack, Thomas Pollmächer, Janet M. Mullington

Brain Behavior and Immunity > 2004 > 18 > 4 > 361-367

There is very little published information on the diurnal variation of cytokines and their receptors, in healthy individuals during normal sleep-wake patterns or during sustained wakefulness. The aim of the current investigation was to characterize concentrations of soluble tumor necrosis factor receptors (sTNF-Rs) and interleukin-2 receptor (sIL-2R) during normal sleep and wakefulness, as well as...

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Hypothalamo-pituitary-adrenal function in patients with depressive disorders is correlated with baseline cytokine levels, but not with cytokine responses to hydrocortisone

Andreas Schuld, Dagmar A. Schmid, Monika Haack, Florian Holsboer, more

Journal of Psychiatric Research > 2003 > 37 > 6 > 463-470

Dysfunction of the hyopthalamo-pituitary adrenal (HPA) system is frequently found in major depression. In addition, signs of non-specific inflammatory system activation have been reported. However, very little is known about interactions between the HPA and immune systems in depressive patients. To assess HPA system function, we performed a combined dexamethasone suppression and corticotropin-releasing...

article

Diurnal variations of interleukin-6 plasma levels are confounded by blood drawing procedures

Monika Haack, Thomas Kraus, Andreas Schuld, Mira Dalal, more

Psychoneuroendocrinology > 2002 > 27 > 8 > 921-931

Recent findings suggest that inflammatory cytokines are involved in sleep regulation. In part, this idea is based on studies showing that systemic levels of interleukin-6 (IL-6) are affected by sleep and sleep deprivation. However, intravenous (IV) catheters used for repetitive blood sampling were reported to increase local IL-6 production, which might confound sleep-dependent or circadian changes...

article

Low levels of circulating inflammatory cytokines-Do they affect human brain functions?

Thomas Pollmächer, Monika Haack, Andreas Schuld, Abraham Reichenberg, more

Brain Behavior and Immunity > 2002 > 16 > 5 > 525-532

Animal studies provide consistent evidence for the pivotal role of inflammatory cytokines in inducing sickness behavior during systemic infection and inflammation. Because depression in humans shows a considerable symptomatic overlap with sickness behavior, it has been hypothesized that cytokines are also involved in affective disorders. This view is supported by studies showing that therapeutic administration...

article

Effects of dexamethasone on cytokine plasma levels and white blood cell counts in depressed patients

Andreas Schuld, Thomas Kraus, Monika Haack, Dunja Hinze-Selch, more

Psychoneuroendocrinology > 2001 > 26 > 1 > 65-76

In major depression, alterations of some aspects of the host defense system and the hypothalamo-pituitary-adrenal (HPA) system have been reported. Both systems are closely related, but their interaction in major depression has not yet been explored. Moreover, little is known about the effects of glucocorticoids on the circulating amounts of cytokines in humans in the absence of immunological challenges...

article

Effects of antipsychotic drugs on cytokine networks

Thomas Pollmächer, Monika Haack, Andreas Schuld, Thomas Kraus, more

Journal of Psychiatric Research > 2000 > 34 > 6 > 369-382

It has been known since the 1950s that phenothiazines have immunomodulatory effects. This review summarizes recent evidence suggesting that antipsychotic drugs, in particular chlorpromazine and the atypical compound clozapine, influence the production of cytokines. Cytokines, organized in networks of related peptides with pleiotropic functions, are pivotal humoral mediators of infection and inflammation,...

article

EFFECTS OF AN INTRAVENOUS CATHETER ON THE LOCAL PRODUCTION OF CYTOKINES AND SOLUBLE CYTOKINE RECEPTORS IN HEALTHY MEN

Monika Haack, Avi Reichenberg, Thomas Kraus, Andreas Schuld, more

Cytokine > 2000 > 12 > 6 > 694-698

Like many aspects of physiology, functions of the immune system show considerable diurnal variation. Studies investigating diurnal variations in the circulating amounts of cytokines, in general, used blood samples obtained from an intravenous catheter. The results of such studies may be confounded by an effect of the catheter on local cytokine production. We measured the levels of IL-6, tumour necrosis...

article

Schlaf und Schläfrigkeit im Rahmen von Infektionen und im Rahmen experimenteller Immunmodulation beim Menschen

Thomas Pollmächer, Andreas Schuld, Thomas Kraus, Monika Haack, more

Somnologie > 2000 > 4 > 2 > 68-78

Infektionen, Entzündungen und Autoimmunprozesse sind von erheblichen Störungen des Wohlbefindens, der beruflichen und sozialen Leistungsfähigkeit, der kognitiven Funktionen und des Verhaltens begleitet. Insbesondere das Schlaf-Wach-Verhalten reagiert auf immunologische Prozesse sehr sensitiv. In der vorliegenden Übersichtsarbeit wird der gegenwärtige Stand des Wissens zum Einfluss einerseits von Infektionen...

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