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Some immunological and psychopathological processes are supposed to be calmodulin-dependent. We studied level of serum autoantibodies against brain extract (BEA), encephalitogenic peptide (EPA), calmodulin (CMA) using ELISA in 72 patients with psychogenic depression and schizophrenia during therapy including psychopharmacologic preparations and thymus peptides. 48 healthy donors and 4 patients with...
Effect of thymus peptides is supposed to be associated with common immunotropic and psychotropic properties. Three groups of laboratory animals (1 - without stress or intact, 2 - stress-induced, 3 - catatony-predisposed rats) were investigated. Animals recieved a total of five daily injections of thymogen at doses 250, 100, 15 mcg/kg or saline. Behaviour in the open field and cross-like maze, reflector...
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