Search results for: Qi Shu

Items from 1 to 20 out of 73 results

article

Electroacupuncture alleviates myocardial ischemia–reperfusion injury by inhibiting hypothalamic paraventricular nucleus neurons projecting to the rostral ventrolateral medulla

Qi Shu, Jie Zhou, Bin Zhang, Fan Zhang, more

European Journal of Neuroscience > 60 > 5 > 4861 - 4876

Accumulating evidence suggests that electroacupuncture (EA) has obvious therapeutic effects and unique advantages in alleviating myocardial ischemia–reperfusion injury (MIRI), while the underlying neuromolecular mechanisms of EA intervention for MIRI have not been fully elucidated. The aim of the study is to investigate the role of the neural pathway of hypothalamic paraventricular nucleus (PVN) neurons...

article

Degradation of citrinin by different types of light and hydrogen peroxide

Xiaowei Zhang, Penghui Wang, Jing Li, Qi Shu, more

Journal of Food Science > 89 > 9 > 6051 - 6059

Abstract Citrinin (CIT), a mycotoxin produced by Monascus, Penicillium, and other fungies, can contaminate red yeast rice and other foods, thus constraining their application and development. Exploring efficient degradation methods of citrinin is becoming as one of the hot research topics. In this study, the degradation of citrinin, irradiated by visible (Vis) light, ultraviolet (UV) light, and simulated...

article

Aldehyde dehydrogenase 2 deficiency reinforces formaldehyde‐potentiated pro‐inflammatory responses and glycolysis in macrophages

Huijuan Ma, Kaiyan Lou, Qi Shu, Xiaodong Song, more

Journal of Biochemical and Molecular Toxicology > 38 > 1 > n/a - n/a

Aldehyde dehydrogenase 2 (ALDH2) deficiency caused by genetic variant is present in more than 560 million people of East Asian descent, which can be identified by apparent facial flushing from acetaldehyde accumulation after consuming alcohol. Recent findings indicated that ALDH2 also played a critical role in detoxification of formaldehyde (FA). Our previous studies showed that FA could enhance...

article

Population Pharmacokinetics of Anlotinib, a Multiple Receptor Tyrosine Kinase Inhibitor, in Chinese Patients With Malignant Tumors

Gaoqi Xu, Dihong Yang, Qi Shu, Junfeng Zhu, more

The Journal of Clinical Pharmacology > 63 > 7 > 830 - 837

The objective of this study was to investigate the pharmacokinetic behavior of anlotinib in Chinese patients with malignant tumors using the population approach. A total of 407 anlotinib plasma concentrations from 16 patients were analyzed in this study. Anlotinib was administered orally 12 or 16 mg in the single‐dose phase and 12 mg once daily in the multiple‐dose phase. A population pharmacokinetic...

article

Electrochemical Immunosensor for the Sensitive Detection of Alzheimer's Biomarker Amyloid‐β (1–42) Using the Heme‐amyloid‐β (1–42) Complex as the Signal Source

Minling Ding, Qi Shu, Nan Zhang, Chaoren Yan, more

Electroanalysis > 34 > 2 > 263 - 274

The amyloid‐β peptide (1–42) (Aβ₄₂) can provide high diagnostic accuracy for the early diagnosis of Alzheimer's disease (AD). In this study, an immunosensor based on the peroxidase‐like activity of heme‐Aβ₄₂ was designed for Aβ₄₂ detection. The glassy carbon electrode (GCE) was electrodeposited Au particles (GCE/Au). The GCE/Au was modified using polythionine‐methylene blue (PTH−MB), AuNPs, monoclonal...

article

Predictive diagnosis of chronic obstructive pulmonary disease using serum metabolic biomarkers and least‐squares support vector machine

Hong Zheng, Yiran Hu, Li Dong, Qi Shu, more

Journal of Clinical Laboratory Analysis > 35 > 2 > n/a - n/a

Objective Development of biofluid‐based biomarkers is attractive for the diagnosis of chronic obstructive pulmonary disease (COPD) but still lacking. Thus, here we aimed to identify serum metabolic biomarkers for the diagnosis of COPD. Methods In this study, we investigated serum metabolic features between COPD patients (n = 54) and normal individuals (n = 74) using a ¹H NMR‐based metabolomics...

article

A DFT study on graphene‐based surface‐enhanced Raman spectroscopy of Benzenedithiol adsorbed on gold/graphene

Ting‐Ting You, Nan Yang, Ying‐Qi Shu, Peng‐Gang Yin

Journal of Raman Spectroscopy > 50 > 10 > 1510 - 1518

In this study, a detailed analysis on the surface‐enhanced Raman scattering of 1,4‐Benzenedithiol adsorbed on gold/graphene cluster is presented by density functional theory calculations. Results indicate that changing graphene type including perfect graphene, monovacancy graphene, B/N‐doped grapheme, and graphene oxide enables modulation of interaction between molecule, gold, and graphene cluster...

article

Quantifying the importance of interannual, interdecadal and multidecadal climate natural variabilities in the modulation of global warming rates

Meng Wei, Fangli Qiao, Yongqing Guo, Jia Deng, more

Climate Dynamics > 2019 > 53 > 11 > 6715-6727

Despite the monotonically rising greenhouse gas emission, global warming rate changes again and again, especially the slowdown during 1998–2013, challenging the current global temperature change mechanisms. Recently, different-scale natural climate variabilities have been individually recognized as the potential causes of global warming rate change, particularly the recent warming slowdown, but disagreements...

article

Assessment of the Atlantic water layer in the Arctic Ocean in CMIP5 climate models

Qi Shu, Qiang Wang, Jie Su, Xiang Li, more

Climate Dynamics > 2019 > 53 > 9-10 > 5279-5291

Atlantic water (AW) plays an important role in the thermal balance of the Arctic Ocean, but thus far there has been no comprehensive assessment of the AW layer in the Arctic Ocean simulated by coupled climate models in the framework of Coupled Model Intercomparison Project (CMIP). In this study we assessed the climatology and the trend of the Arctic AW layer in the historical simulations of 41 CMIP5...

article

Application of artificial intelligence in pediatrics: past, present and future

Li-Qi Shu, Yi-Kan Sun, Lin-Hua Tan, Qiang Shu, more

World Journal of Pediatrics > 2019 > 15 > 2 > 105-108

article

Autism spectrum disorders: autistic phenotypes and complicated mechanisms

Xi-Cheng Zhang, Li-Qi Shu, Xing-Sen Zhao, Xue-Kun Li

World Journal of Pediatrics > 2019 > 15 > 1 > 17-25

Background Autism spectrum disorder (ASD), a pervasive developmental neurological disorder, is characterized by impairments in social interaction and communication, and stereotyped, repetitive patterns of interests or behaviors. The mechanism of ASDs is complex, and genetic components and epigenetic modifications play important roles. In this review, we summarized the recent progresses of ASDs focusing...

article

Balancing metabolome coverage and reproducibility for untargeted NMR-based metabolic profiling in tissue samples through mixture design methods

Hong Zheng, Zhitao Ni, Aimin Cai, Xi Zhang, more

Analytical and Bioanalytical Chemistry > 2018 > 410 > 29 > 7783-7792

Untargeted metabolomics attempts to acquire a comprehensive and reproducible set of small-molecule metabolites in biological systems. However, metabolite extraction method significantly affects the quality of metabolomics data. In the present study, we calculated the number of peaks (NP) and coefficient of variation (CV) to reflect metabolome coverage and reproducibility in untargeted NMR-based metabolic...

article

Separating effects of clonal integration on plant growth during submergence and de-submergence

Guan-Wen Wei, Qi Shu, Fang-Li Luo, Yu-Han Chen, more

Flora - Morphology, Distribution, Functional Ecology of Plants > 2018 > 246-247 > C > 118-125

Responses to both submergence and de-submergence are important for evaluating flood tolerance of plants. Clonal integration (resource translocation between connected ramets within clones) has been shown to increase flood tolerance of amphibious clonal plants. However, no study has truly separated the effects of clonal integration during de-submergence from those during submergence. We grew 40 clonal...

article

Gravitation waves from QCD and electroweak phase transitions

Yidian Chen, Mei Huang, Qi-Shu Yan

Journal of High Energy Physics > 2018 > 2018 > 5 > 1-24

Abstract We investigate the gravitation waves produced from QCD and electroweak phase transitions in the early universe by using a 5-dimension holographic QCD model and a holographic technicolor model. The dynamical holographic QCD model is to describe the pure gluon system, where a first order confinement-deconfinement phase transition can happen at the critical temperature around 250 MeV. The minimal...

article

Evaluation on data assimilation of a global high resolution wave-tide-circulation coupled model using the tropical Pacific TAO buoy observations

Junqiang Shi, Xunqiang Yin, Qi Shu, Bin Xiao, more

Acta Oceanologica Sinica > 2018 > 37 > 3 > 8-20

In order to evaluate the assimilation results from a global high resolution ocean model, the buoy observations from tropical atmosphere ocean (TAO) during August 2014 to July 2015 are employed. The horizontal resolution of wave-tide-circulation coupled ocean model developed by The First Institute of Oceanography (FIOCOM model) is 0.1°×0.1°, and ensemble adjustment Kalman filter is used to assimilate...

article

Spatiotemporal evolution of the chlorophyll a trend in the North Atlantic Ocean

Min Zhang, Yuanling Zhang, Qi Shu, Chang Zhao, more

Science of The Total Environment > 2018 > 612 > C > 1141-1148

Analyses of the chlorophyll a concentration (chla) from satellite ocean color products have suggested the decadal-scale variability of chla linked to the climate change. The decadal-scale variability in chla is both spatially and temporally non-uniform. We need to understand the spatiotemporal evolution of chla in decadal or multi-decadal timescales to better evaluate its linkage to climate variability...

article

Earthquake dynamic response behavior of Xiangchong valley type tailings impoundment in Yunnan, China

Zhe Ren, Kun Wang, Qi-shu Zhang, Ze-min Xu, more

Journal of Mountain Science > 2018 > 15 > 1 > 82-99

Tailings impoundments can potentially collapse due to damage caused by earthquakes, which has frequently occurred around the world. This study takes the proposed valley type tailings impoundment in Yunnan as the research object to analyze the dynamic response behavior under earthquake action with both numerical simulation and physical model test (1:300). The results of both tests show that the dynamic...

article

Link between the Barents Oscillation and recent boreal winter cooling over the Asian midlatitudes

Qi Shu, Fangli Qiao, Zhenya Song, Yajuan Song

Advances in Atmospheric Sciences > 2018 > 35 > 1 > 127-132

The link between boreal winter cooling over the midlatitudes of Asia and the Barents Oscillation (BO) since the late 1980s is discussed in this study, based on five datasets. Results indicate that there is a large-scale boreal winter cooling during 1990–2015 over the Asian midlatitudes, and that it is a part of the decadal oscillations of long-term surface air temperature (SAT) anomalies. The SAT...

article

New physics in multi-Higgs boson final states

Wolfgang Kilian, Sichun Sun, Qi-Shu Yan, Xiaoran Zhao, more

Journal of High Energy Physics > 2017 > 2017 > 6 > 1-49

Abstract We explore the potential for the discovery of the triple-Higgs signal in the decay channel at a 100 TeV hadron collider. We consider both the Standard Model and generic new-physics contributions, described by an effective Lagrangian that includes higher-dimensional operators. The selected subset of operators is motivated by composite-Higgs and Higgs-inflation models. In the Standard Model,...

article

Effect of increasing Arctic river runoff on the Atlantic meridional overturning circulation: a model study

Qi Shu, Fangli Qiao, Zhenya Song, Bin Xiao

Acta Oceanologica Sinica > 2017 > 36 > 8 > 59-65

An increasing amount of freshwater has been observed to enter the Arctic Ocean from the six largest Eurasian rivers over the past several decades. The increasing trend is projected to continue in the twenty-first century according to Coupled Model Intercomparison Project Phase 5 (CMIP5) coupled models. The present study found that water flux from rivers to the Arctic Ocean at the end of the century...

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INFONA - science communication portal

Search results for: Qi Shu

Electroacupuncture alleviates myocardial ischemia–reperfusion injury by inhibiting hypothalamic paraventricular nucleus neurons projecting to the rostral ventrolateral medulla

Degradation of citrinin by different types of light and hydrogen peroxide

Aldehyde dehydrogenase 2 deficiency reinforces formaldehyde‐potentiated pro‐inflammatory responses and glycolysis in macrophages

Population Pharmacokinetics of Anlotinib, a Multiple Receptor Tyrosine Kinase Inhibitor, in Chinese Patients With Malignant Tumors

Electrochemical Immunosensor for the Sensitive Detection of Alzheimer's Biomarker Amyloid‐β (1–42) Using the Heme‐amyloid‐β (1–42) Complex as the Signal Source

Predictive diagnosis of chronic obstructive pulmonary disease using serum metabolic biomarkers and least‐squares support vector machine

A DFT study on graphene‐based surface‐enhanced Raman spectroscopy of Benzenedithiol adsorbed on gold/graphene

Quantifying the importance of interannual, interdecadal and multidecadal climate natural variabilities in the modulation of global warming rates

Assessment of the Atlantic water layer in the Arctic Ocean in CMIP5 climate models

Application of artificial intelligence in pediatrics: past, present and future

Autism spectrum disorders: autistic phenotypes and complicated mechanisms

Balancing metabolome coverage and reproducibility for untargeted NMR-based metabolic profiling in tissue samples through mixture design methods

Separating effects of clonal integration on plant growth during submergence and de-submergence

Gravitation waves from QCD and electroweak phase transitions

Evaluation on data assimilation of a global high resolution wave-tide-circulation coupled model using the tropical Pacific TAO buoy observations

Spatiotemporal evolution of the chlorophyll a trend in the North Atlantic Ocean

Earthquake dynamic response behavior of Xiangchong valley type tailings impoundment in Yunnan, China

Link between the Barents Oscillation and recent boreal winter cooling over the Asian midlatitudes

New physics in multi-Higgs boson final states

Effect of increasing Arctic river runoff on the Atlantic meridional overturning circulation: a model study

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