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The mbd cluster encoding genes of the 3‐methylbenzoyl‐CoA pathway involved in the anaerobic catabolism of 3‐methylbenzoate and m‐xylene was characterized for the first time in the denitrifying β‐Proteobacterium Azoarcus sp. CIB. The mbdA gene product was identified as a 3‐methylbenzoate‐CoA ligase required for 3‐methylbenzoate activation; its substrate spectrum was unique in activating all three methylbenzoate...
The biochemistry of nicotinic acid (NA) degradation is known but the transcriptional control of the genes involved is still poorly studied. We report here the transcriptional regulatory circuit of the nic genes responsible for the aerobic degradation of NA in Pseudomonas putida KT2440. The three NA‐inducible catabolic operons, i.e. nicAB, encoding the upper pathway that converts NA into 6‐hydroxynicotinic...