Search results for: Yuki Koga

Items from 1 to 20 out of 22 results

article

Clinical significance of evaluating endoscopic response to neoadjuvant chemotherapy in esophageal squamous cell carcinoma

Yohei Nagai, Naoya Yoshida, Yoshifumi Baba, Kazuto Harada, more

Background and Aim Clinical significance of endoscopic response (ER) after neoadjuvant chemotherapy (NAC) for esophageal cancer has not been fully understood. Thus, the present study aimed to investigate the association between ER to NAC and its clinicopathological outcomes in patients with esophageal squamous cell carcinoma (ESCC). Methods In total, 141 patients who underwent NAC and subsequent...

article

Fabrication of regular arrays of organic crystalline needles using creases formed on oxidized poly(dimethylsiloxane) surfaces

Masashi Watanabe, Yuki Koga, Hiroko Ichikawa

Journal of Applied Polymer Science > 136 > 27 > n/a - n/a

In this study, creases are regularly self‐assembled on the oxidized surface of poly(dimethylsiloxane) by swelling‐induced buckling instability. These creases are then used as templates for the regular arrangement of crystalline needles. The solution of an organic compound is confined in the aligned creases and dried to generate a crystalline needle in each crease. Thus, the orientation of the crystalline...

article

Preservation of physiological passage through the remnant stomach prevents postoperative malnutrition after proximal gastrectomy with double tract reconstruction

Kohei Yamashita, Masaaki Iwatsuki, Yuki Koga, Tasuku Toihata, more

Surgery Today > 2019 > 49 > 9 > 748-754

Purpose Double tract reconstruction (DT) after proximal gastrectomy (PG) is considered beneficial for postoperative nutrition status by preserving the physiological passage of food. We conducted this study to assess postoperative nutrition status based on food passage after this operation. Methods The subjects of this retrospective study were 63 patients who underwent PG with DT. The patients were...

article

The role of FBXW7, a cell-cycle regulator, as a predictive marker of recurrence of gastrointestinal stromal tumors

Yuki Koga, Masaaki Iwatsuki, Kohei Yamashita, Yuki Kiyozumi, more

Gastric Cancer > 2019 > 22 > 6 > 1100-1108

Background Few reliable prognostic markers have been established despite elucidation of the molecular mechanisms of gastrointestinal stromal tumor (GIST) development. We evaluated F-box and WD repeat domain-containing 7 (FBXW7), a cell-cycle-regulating and tumor suppressor, in GISTs. We aimed to determine the clinical relevance of FBXW7 in GISTs and characterize the molecular mechanism of FBXW7 in...

article

In–Ga–Zn–O Thin-Film Devices As Synapse Elements in a Neural Network

Mutsumi Kimura, Yuki Koga, Hiroki Nakanishi, Tokiyoshi Matsuda, more

IEEE Journal of the Electron Devices Society > 2018 > 6 > 1 > 100 - 105

We have succeeded in utilizing In–Ga–Zn–O (IGZO) thin-film devices as synapse elements in a neural network. The electrical conductance is regarded as the connection strength, and the continuous change by flowing electrical current is employed as the connection plasticity based on the modified Hebbian learning as a learning rule. We developed a cellular neural network using the IGZO thin-film devices...

article

Complete remission of advanced hepatocellular carcinoma following transient chemoembolization and portal vein ligation

Yuki Koga, Toru Beppu, Katsunori Imai, Kunitaka Kuramoto, more

Surgical Case Reports > 2018 > 4 > 1 > 1-6

Background Macroscopic diffuse-type hepatocellular carcinoma with concomitant major portal vein tumor thrombus (PVTT) and peritoneal dissemination indicates poor prognosis. Additionally, triple-positive tumor marker status is a predictor of poor outcome even after hepatectomy. Sorafenib is recommended in such patients, but it has limited therapeutic effectiveness. Case presentation A 54-year-old...

article

PLOD2 as a potential regulator of peritoneal dissemination in gastric cancer

Yuki Kiyozumi, Masaaki Iwatsuki, Junji Kurashige, Yoko Ogata, more

International Journal of Cancer > 143 > 5 > 1202 - 1211

Peritoneal dissemination is the most common metastatic pattern in advanced gastric cancer (GC) and has a very poor prognosis. However, its molecular mechanism has not been elucidated. Our study investigated genes associated with peritoneal dissemination of GC. We performed combined expression analysis of metastatic GC cell lines and identified Procollagen‐lysine, 2‐oxoglutarate 5‐dioxygenase2 (PLOD2)...

article

The association of the lymph node ratio and serum carbohydrate antigen 19-9 with early recurrence after curative gastrectomy for gastric cancer

Hiroshi Sawayama, Masaaki Iwatsuki, Daisuke Kuroda, Tasuku Toihata, more

Surgery Today > 2018 > 48 > 11 > 994-1003

Purpose This study investigated the predictors associated with early recurrence (i.e. within 12 months) after curative gastrectomy for gastric cancer (GC). Methods We evaluated the clinicopathological factors in 429 patients who underwent curative gastrectomy for GC without preoperative chemotherapy and analyzed these factors’ associations with early recurrence. Results Of 429 patients, 57 experienced...

article

Total iron-binding capacity is a novel prognostic marker after curative gastrectomy for gastric cancer

Hiroshi Sawayama, Masaaki Iwatsuki, Daisuke Kuroda, Tasuku Toihata, more

International Journal of Clinical Oncology > 2018 > 23 > 4 > 671-680

Background Patients with gastric cancer (GC) are affected by changes in iron status. Before surgery, GC patients are likely to have iron-deficiency anemia; and after gastrectomy, patients suffer from low nutritional status and low iron. This study investigated preoperative iron status associated with prognosis after curative gastrectomy for gastric cancer. Methods We evaluated preoperative serum...

article

Prognostic Factors of Salvage Esophagectomy for Residual or Recurrent Esophageal Squamous Cell Carcinoma After Definitive Chemoradiotherapy

Yuki Kiyozumi, Naoya Yoshida, Takatsugu Ishimoto, Taisuke Yagi, more

World Journal of Surgery > 2018 > 42 > 9 > 2887-2893

Background The aim of this study was to confirm prognostic factors for salvage esophagectomy for remnant or recurrent esophageal squamous cell carcinoma after definitive chemoradiotherapy. Study design We retrospectively analyzed clinicopathological backgrounds of 50 patients who underwent salvage esophagectomy between April 2005 and January 2016. Salvage esophagectomy comprised 40 three-incision...

article

Histopathological and genetic review of phosphaturic mesenchymal tumours, mixed connective tissue variant

Yuichi Yamada, Izumi Kinoshita, Kohashi Kenichi, Hidetaka Yamamoto, more

Histopathology > 72 > 3 > 460 - 471

Aims Phosphaturic mesenchymal tumour, mixed connective tissue variant (PMT‐MCT), is a tumour of uncertain differentiation, characterised by ‘smudgy/grungy’ calcification and vitamin D‐resistant phosphaturic osteomalacia. Fibroblast growth factor (FGF)23 is recognised as a reliable marker of PMT‐MCT, but quantitative evaluation has never been performed. We reviewed cases of tumour‐associated osteomalacia...

article

Enhancement of transdermal protein delivery by photothermal effect of gold nanorods coated on polysaccharide-based hydrogel

Aung Thu Haine, Yuki Koga, Yuta Hashimoto, Taishi Higashi, more

European Journal of Pharmaceutics and Biopharmaceutics > 2017 > 119 > C > 91-95

Transdermal protein delivery is a useful and attractive method for protein therapy and dermal vaccination. However, this delivery method is restricted by the low permeability of the stratum corneum. The purpose of this study was to develop a transdermal delivery system for enhancement of protein permeability into the skin. First, we prepared a transparent gel patch made of polysaccharides with gold...

chapter

Planar device using In-Ga-Zn-O semiconductor for synapse element in neural network

Daiki Yamakawa, Yuki Koga, Keisuke Ikushima, Kenta Umeda, more

2017 IEEE International Meeting for Future of Electron Devices, Kansai (IMFEDK) > 72 - 73

2017 IEEE International Meeting for Future of Electron Devices, Kansai (IMFEDK)

We have developed a planar device using In-Ga-Zn-O (IGZO) semiconductor for synapse element in neural network. First, we formed the planar device on a glass substrate. Next, we formed it on an LSI wafer. Both devices shows proper uniformities of film thicknesses and sufficient degradations of electric characteristics, which can be utilized for modified Hebbian learning proposed by us. These results...

chapter

Cross-point device using In-Ga-Zn-O semiconductor for synapse element in neural network

Ryo Tanaka, Yuki Koga, Keisuke Ikushima, Kenta Umeda, more

2017 IEEE International Meeting for Future of Electron Devices, Kansai (IMFEDK) > 62 - 63

2017 IEEE International Meeting for Future of Electron Devices, Kansai (IMFEDK)

We have developed a cross-point device using In-Ga-Zn-O (IGZO) semiconductor for synapse element in neural network. Horizontal 80 and vertical 80 metal lines make 6400 cross-point synapse integrated on a glass substrate. The electrical conductance gradually degrades by flowing current, which is available for modified Hebbian learning.

chapter

Neural network using FPGA for neurons and IGZO thin films for synapses

Yuki Koga, Tokiyoshi Matsuda, Mutsumi Kimura

2016 23rd International Workshop on Active-Matrix Flatpanel Displays and Devices (AM-FPD) > 179 - 180

2016 23rd International Workshop on Active-Matrix Flatpanel Displays and Devices (AM-FPD)

Neural networks are computing models based on human brains. We propose a neural network using a field-programmable gate array (FPGA) for neurons and amorphous In-Ga-Zn-O (a-IGZO) thin films for synapses. It is found that electric current in the a-IGZO thin film gradually decreases along the time. On the other hand, the degradation does not occur when light is irradiated. These phenomena can be utilized...

article

Effective VCR/DEX pulse maintenance therapy in the KYCCSG ALL-02 protocol for pediatric acute lymphoblastic leukemia

Yasuhiro Okamoto, Yuki Koga, Jiro Inagaki, Shuichi Ozono, more

International Journal of Hematology > 2016 > 103 > 2 > 202-209

In a previous study of childhood acute lymphoblastic leukemia (ALL) by the Kyushu–Yamaguchi Children’s Cancer Study Group, ALL-96, we achieved a 72.1 % 5-year event-free survival (EFS) and an 84.8 % 5-year overall survival (OS). In a subsequent study, ALL-02, we adopted a vincristine dexamethasone (VCR/DEX) pulse regimen as maintenance therapy in the context of the ALL-96 study using the same risk...

chapter

Frequency modulation-type capacitance sensor using amorphous In-Ga-Zn-O thin-film transistors

Yuki Koga, Tokiyoshi Matsuda, Mamoru Furuta, Mutsumi Kimura

2015 22nd International Workshop on Active-Matrix Flatpanel Displays and Devices (AM-FPD) > 139 - 140

2015 22nd International Workshop on Active-Matrix Flatpanel Displays and Devices (AM-FPD)

We have developed a frequency modulation-type capacitance sensor using amorphous In-Ga-Zn-O (α-IGZO) thin-film transistors (TFTs) for integrated touchpanels. This capacitance sensor consists of a ring oscillator, whose one stage is replaced by a reset transistor, sensing transistor, and sensing electrode. The sensing electrode becomes one terminal when the other terminal is added by finger to form...

article

Multiple skeletal muscle metastases from poorly differentiated gastric adenocarcinoma

Yuki Koga, Yoshifumi Baba, Kazuto Harada, Keisuke Kosumi, more

Surgical Case Reports > 2015 > 1 > 1 > 1-5

We report here a rare case of gastric carcinoma with multiple intramuscular metastases. A 71-year-old man presented with rapidly evolving swelling of his left thigh and severe pain. Three years earlier, he had undergone neoadjuvant chemotherapy followed by gastrectomy for advanced gastric cancer. A computed tomography scan showed unusual swellings in multiple skeletal muscles with no vessel or bone...

article

Breast cancer recurrence in esophagus, stomach, and liver, 15 years following primary surgery: report of a case

Yuki Koga, Yoshifumi Baba, Ryuichi Karashima, Shiro Iwagami, more

International Cancer Conference Journal > 2015 > 4 > 3 > 172-175

Metastasis of breast cancer to the gastrointestinal tract is relatively rare. We hereby report a case of breast cancer recurrence in the esophagus, stomach, and liver, 15 years following primary surgery. A 67-year-old woman presented with a 2-month history of dysphagia. Fifteen years previously, she had undergone right mastectomy for breast carcinoma. Upper gastrointestinal endoscopy revealed circumferential...

article

Acute ST elevation myocardial infarction in an adult patient with anomalous origin of the left coronary artery from the pulmonary artery

Takashi Omura, Keitaro Ogawa, Mayu Hashimoto, Ryoko Kitada, more

Journal of Cardiology Cases > 2014 > 9 > 3 > 121-123

Anomalous origin of the left coronary artery from the pulmonary artery is rare but causes myocardial ischemia and sudden death. A few patients with this anomaly can survive to adulthood without sufficient collateral coronary flow or surgical intervention. We present here a case of acute inferior myocardial infarction, which may occur due to thrombotic occlusion of the right coronary artery, in a 63-year-old...

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INFONA - science communication portal

Search results for: Yuki Koga

Clinical significance of evaluating endoscopic response to neoadjuvant chemotherapy in esophageal squamous cell carcinoma

Fabrication of regular arrays of organic crystalline needles using creases formed on oxidized poly(dimethylsiloxane) surfaces

Preservation of physiological passage through the remnant stomach prevents postoperative malnutrition after proximal gastrectomy with double tract reconstruction

The role of FBXW7, a cell-cycle regulator, as a predictive marker of recurrence of gastrointestinal stromal tumors

In–Ga–Zn–O Thin-Film Devices As Synapse Elements in a Neural Network

Complete remission of advanced hepatocellular carcinoma following transient chemoembolization and portal vein ligation

PLOD2 as a potential regulator of peritoneal dissemination in gastric cancer

The association of the lymph node ratio and serum carbohydrate antigen 19-9 with early recurrence after curative gastrectomy for gastric cancer

Total iron-binding capacity is a novel prognostic marker after curative gastrectomy for gastric cancer

Prognostic Factors of Salvage Esophagectomy for Residual or Recurrent Esophageal Squamous Cell Carcinoma After Definitive Chemoradiotherapy

Histopathological and genetic review of phosphaturic mesenchymal tumours, mixed connective tissue variant

Enhancement of transdermal protein delivery by photothermal effect of gold nanorods coated on polysaccharide-based hydrogel

Planar device using In-Ga-Zn-O semiconductor for synapse element in neural network

Cross-point device using In-Ga-Zn-O semiconductor for synapse element in neural network

Neural network using FPGA for neurons and IGZO thin films for synapses

Effective VCR/DEX pulse maintenance therapy in the KYCCSG ALL-02 protocol for pediatric acute lymphoblastic leukemia

Frequency modulation-type capacitance sensor using amorphous In-Ga-Zn-O thin-film transistors

Multiple skeletal muscle metastases from poorly differentiated gastric adenocarcinoma

Breast cancer recurrence in esophagus, stomach, and liver, 15 years following primary surgery: report of a case

Acute ST elevation myocardial infarction in an adult patient with anomalous origin of the left coronary artery from the pulmonary artery

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