Search results for: Yasuo Miura

Items from 1 to 20 out of 31 results

article

Aberrant buffy coat formation during leukodepletion for hyperleukocytosis in a case of primary myelofibrosis‐transforming acute myeloid leukemia

Hideaki Matsuura, Sumie Fujii, Yasunori Ueda, Yasuo Miura

Transfusion > 63 > 8 > 1420 - 1422

article

Feasibility of the automated column agglutination technique for titration of anti‐A/B antibodies in ABO‐incompatible living kidney transplantation

Hideaki Matsuura, Yukari Sugiura, Takahiro Matsuno, Yume Tomiya, more

Therapeutic Apheresis and Dialysis > 26 > 4 > 827 - 835

Introduction Quantitative measurement of anti‐A/‐B antibody titers is important during ABO‐incompatible living kidney transplantation (ABOi‐LKT). Methods We conducted a multi‐institutional study to measure the antibody titers using the automated column agglutination technique (auto‐CAT) and tube test (TT) method in ABOi‐LKT recipients. Statistical analysis was performed to evaluate the two methods...

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Prolonged incubation period of hepatitis B in a recipient of a nucleic acid amplification test‐negative hepatitis B virus window donation

Takahiro Matsuno, Hideaki Matsuura, Sumie Fujii, Ami Tanaka, more

Transfusion > 61 > 9 > 2782 - 2787

Background The occurrence of transfusion‐transmitted hepatitis B virus (HBV) infection has fallen dramatically due to continuous improvements in pre‐transfusion laboratory testing. However, the characteristics of transfusion‐transmitted HBV infection caused by individual donor nucleic acid amplification test (ID‐NAT)‐negative blood products are unclear. Case Presentation A 76‐year‐old woman with...

article

Successful granulocyte apheresis using medium molecular weight hydroxyethyl starch

Mai Nanya, Kimiko Yurugi, Itaru Kato, Hidefumi Hiramatsu, more

International Journal of Hematology > 2019 > 110 > 6 > 729-735

Granulocyte transfusion (GTX) is a therapeutic option for severe bacterial or fungal infection in patients with sustained neutropenia after chemotherapy or stem cell transplantation. However, high molecular weight hydroxyethyl starch (HES), which has been used for selective sedimentation of red blood cells during apheresis, is not easily available in many countries including Japan. In this study,...

article

Erratum to: Bortezomib interferes with adhesion of B cell precursor acute lymphoblastic leukemia cells through SPARC up-regulation in human bone marrow mesenchymal stromal/stem cells

Masaki Iwasa, Yasuo Miura, Aya Fujishiro, Sumie Fujii, more

International Journal of Hematology > 2017 > 105 > 5 > 704-705

The online version of the original article can be found under doi: 10.1007/s12185-016-2169-x .

article

Bortezomib interferes with adhesion of B cell precursor acute lymphoblastic leukemia cells through SPARC up-regulation in human bone marrow mesenchymal stromal/stem cells

Masaki Iwasa, Yasuo Miura, Aya Fujishiro, Sumie Fujii, more

International Journal of Hematology > 2017 > 105 > 5 > 587-597

The poor prognosis of adults with B cell precursor acute lymphoblastic leukemia (BCP-ALL) is attributed to leukemia cells that are protected by the bone marrow (BM) microenvironment. In the present study, we explored the pharmacological targeting of mesenchymal stromal/stem cells in BM (BM-MSCs) to eliminate chemoresistant BCP-ALL cells. Human BCP-ALL cells (NALM-6 cells) that adhered to human BM-MSCs...

article

Pharmacological targeting of bone marrow mesenchymal stromal/stem cells for the treatment of hematological disorders

Noriko Sugino, Tatsuo Ichinohe, Akifumi Takaori-Kondo, Taira Maekawa, more

Inflammation and Regeneration > 2017 > 37 > 1 > 1-7

The therapeutic effects of mesenchymal stromal/stem cells (MSCs) are mainly based on three characteristics: immunomodulation, tissue regeneration, and hematopoietic support. Cell therapy using culture-expanded MSCs is effective in some intractable bone and hemato-immune disorders; however, its efficacy is limited. In this article, we review the previous efforts to improve the clinical outcomes of...

article

Effects of acute exposure to low-dose radiation on the characteristics of human bone marrow mesenchymal stromal/stem cells

Aya Fujishiro, Yasuo Miura, Masaki Iwasa, Sumie Fujii, more

Inflammation and Regeneration > 2017 > 37 > 1 > 1-12

Background In recent years, increasing attention has been paid to the effects of low-dose irradiation on human health. We examined whether low-dose irradiation affected the functions of mesenchymal stromal/stem cells (MSCs), which are tissue/organ-supportive stem cells, derived from bone marrow (BM). Methods Normal human BM-MSCs from five healthy individuals were used in this study. Culture-expanded...

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Early osteoinductive human bone marrow mesenchymal stromal/stem cells support an enhanced hematopoietic cell expansion with altered chemotaxis- and adhesion-related gene expression profiles

Noriko Sugino, Yasuo Miura, Hisayuki Yao, Masaki Iwasa, more

Biochemical and Biophysical Research Communications > 2016 > 469 > 4 > 823-829

Bone marrow (BM) microenvironment has a crucial role in supporting hematopoiesis. Here, by using a microarray analysis, we demonstrate that human BM mesenchymal stromal/stem cells (MSCs) in an early osteoinductive stage (e-MSCs) are characterized by unique hematopoiesis-associated gene expression with an enhanced hematopoiesis-supportive ability. In comparison to BM-MSCs without osteoinductive treatment,...

article

Human bone marrow mesenchymal stromal/stem cells: current clinical applications and potential for hematology

Yasuo Miura

International Journal of Hematology > 2016 > 103 > 2 > 122-128

Human mesenchymal stromal/stem cells (MSCs) have capabilities for multi-differentiation, immunomodulation, and hematopoietic support. Based on these unique biological characteristics, human MSCs have been extensively used as a transplantable resource for cell therapy in regenerative medicine, immune diseases, and hematological diseases. One of the most promising therapeutic effects of human MSCs is...

article

Guest editorial: Human mesenchymal stromal/stem cell (MSC)

Yasuo Miura

International Journal of Hematology > 2016 > 103 > 2 > 119-121

article

IFNα promotes differentiation of BCR-ABL+ leukemic cells through upregulating C/EBPβ

Asumi Yokota, Hideyo Hirai, Yoshihiro Hayashi, Akihiro Tamura, more

Experimental Hematology > 2015 > 43 > 9(S) > S104

article

Accelerated apoptosis of peripheral blood monocytes in Cebpb-deficient mice

Akihiro Tamura, Hideyo Hirai, Asumi Yokota, Atsushi Sato, more

Biochemical and Biophysical Research Communications > 2015 > 464 > 2 > 654-658

The CCAAT/enhancer-binding protein β (C/EBPβ) transcription factor is required for granulopoiesis under stress conditions. However, little is known about its roles in steady state hematopoiesis. Here, we analyzed the peripheral blood and bone marrow of Cebpb^−/− mice at steady state by flow cytometry and unexpectedly found that the number of peripheral blood monocytes was severely reduced, while the...

article

An Association Between Amino Acid Position 74 of HLA–DRB1 and Anti–Citrullinated Protein Antibody Levels in Japanese Patients With Anti–Citrullinated Protein Antibody–Positive Rheumatoid Arthritis

Chikashi Terao, Akari Suzuki, Katsunori Ikari, Yuta Kochi, more

Arthritis & Rheumatology > 67 > 8 > 2038 - 2045

ObjectiveAnti–citrullinated protein antibodies (ACPAs) are highly specific to rheumatoid arthritis (RA), and strong associations between HLA–DRB1 alleles and ACPA levels have been detected in RA patients. We undertook this study to elucidate the associations between particular amino acid positions in HLA–DRB1 and ACPA levels in patients with RA. MethodsWe analyzed ACPA data on a total of 4,371 Japanese...

article

Brief Report: Main Contribution of DRB1*04:05 Among the Shared Epitope Alleles and Involvement of DRB1 Amino Acid Position 57 in Association With Joint Destruction in Anti–Citrullinated Protein Antibody–Positive Rheumatoid Arthritis

Chikashi Terao, Koichiro Yano, Katsunori Ikari, Moritoshi Furu, more

Arthritis & Rheumatology > 67 > 7 > 1744 - 1750

Objective The shared epitope is associated with increased joint destruction in rheumatoid arthritis (RA) as well as susceptibility to RA and the production of anti–citrullinated protein antibody (ACPA). However, previous studies addressing whether the association of the shared epitope with joint destruction is independent of ACPA have shown different results in different populations. Different allele...

article

Isolation of mesenchymal stromal/stem cells from small-volume umbilical cord blood units that do not qualify for the banking system

Satoshi Yoshioka, Yasuo Miura, Masaki Iwasa, Aya Fujishiro, more

International Journal of Hematology > 2015 > 102 > 2 > 218-229

The clinical application of mesenchymal stromal/stem cells (MSCs) has been extensively explored. In this study, we examined the availability of freshly donated umbilical cord blood (UCB) units that do not qualify for the Japanese banking system for transplantation because of their small volume as a source of MSCs. Forty-five UCB units were used. The median volume of each UCB unit and number of nucleated...

article

Two Susceptibility Loci to Takayasu Arteritis Reveal a Synergistic Role of the IL12B and HLA-B Regions in a Japanese Population

Chikashi Terao, Hajime Yoshifuji, Akinori Kimura, Takayoshi Matsumura, more

The American Journal of Human Genetics > 2013 > 93 > 2 > 289-297

Takayasu arteritis (TAK) is an autoimmune systemic vasculitis of unknown etiology. Although previous studies have revealed that HLA-B ^∗ 52:01 has an effect on TAK susceptibility, no other genetic determinants have been established so far. Here, we performed genome scanning of 167 TAK cases and 663 healthy controls via Illumina Infinium Human Exome BeadChip arrays, followed by a replication...

article

Serological survey of equine viral diseases in Mongolia

Ochir Pagamjav, Keiko Kobayashi, Hironobu Murakami, Yuji Tabata, more

Microbiology and Immunology > 55 > 4 > 289 - 292

Three hundred sera were collected from horses in various parts of Mongolia in 2007 and seroepidemiological surveys for several equine viruses performed on them. Equid herpesvirus 1 and equine rhinitis A virus were prevalent, and equine arteritis virus and equid herpesvirus 3 were detected over a wide area though their rates of antibody‐positivity were not high. Equine infectious anemia was distributed...

article

Methotrexate-associated lymphoplasmacytic lymphoma complicated with type 2 cryoglobulinemia

Yusuke Matsui, Yasuo Miura, Noriko Sugino, Hitomi Kaneko, more

International Journal of Hematology > 2011 > 93 > 2 > 253-256

Electronic supplementary material The online version of this article (doi: 10.1007/s12185-010-0749-8 ) contains supplementary material, which is available to authorized users.

article

Intravascular large B‐cell lymphoma cells in the bone marrow smear preparation

Yasuo Miura, Yusuke Matsui, Noriko Sugino, Yuko Nakato, more

British Journal of Haematology > 152 > 2 > 237 - 238

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INFONA - science communication portal

Search results for: Yasuo Miura

Aberrant buffy coat formation during leukodepletion for hyperleukocytosis in a case of primary myelofibrosis‐transforming acute myeloid leukemia

Feasibility of the automated column agglutination technique for titration of anti‐A/B antibodies in ABO‐incompatible living kidney transplantation

Prolonged incubation period of hepatitis B in a recipient of a nucleic acid amplification test‐negative hepatitis B virus window donation

Successful granulocyte apheresis using medium molecular weight hydroxyethyl starch

Erratum to: Bortezomib interferes with adhesion of B cell precursor acute lymphoblastic leukemia cells through SPARC up-regulation in human bone marrow mesenchymal stromal/stem cells

Bortezomib interferes with adhesion of B cell precursor acute lymphoblastic leukemia cells through SPARC up-regulation in human bone marrow mesenchymal stromal/stem cells

Pharmacological targeting of bone marrow mesenchymal stromal/stem cells for the treatment of hematological disorders

Effects of acute exposure to low-dose radiation on the characteristics of human bone marrow mesenchymal stromal/stem cells

Early osteoinductive human bone marrow mesenchymal stromal/stem cells support an enhanced hematopoietic cell expansion with altered chemotaxis- and adhesion-related gene expression profiles

Human bone marrow mesenchymal stromal/stem cells: current clinical applications and potential for hematology

Guest editorial: Human mesenchymal stromal/stem cell (MSC)

IFNα promotes differentiation of BCR-ABL+ leukemic cells through upregulating C/EBPβ

Accelerated apoptosis of peripheral blood monocytes in Cebpb-deficient mice

An Association Between Amino Acid Position 74 of HLA–DRB1 and Anti–Citrullinated Protein Antibody Levels in Japanese Patients With Anti–Citrullinated Protein Antibody–Positive Rheumatoid Arthritis

Brief Report: Main Contribution of DRB1*04:05 Among the Shared Epitope Alleles and Involvement of DRB1 Amino Acid Position 57 in Association With Joint Destruction in Anti–Citrullinated Protein Antibody–Positive Rheumatoid Arthritis

Isolation of mesenchymal stromal/stem cells from small-volume umbilical cord blood units that do not qualify for the banking system

Two Susceptibility Loci to Takayasu Arteritis Reveal a Synergistic Role of the IL12B and HLA-B Regions in a Japanese Population

Serological survey of equine viral diseases in Mongolia

Methotrexate-associated lymphoplasmacytic lymphoma complicated with type 2 cryoglobulinemia

Intravascular large B‐cell lymphoma cells in the bone marrow smear preparation

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