Search results for: David Healey

Items from 1 to 11 out of 11 results

article

Slipping rib syndrome

Jonathan Bong, David Healey

Journal of Medical Imaging and Radiation Oncology > 66 > 3 > 409 - 410

Slipping rib syndrome (SRS) is an underdiagnosed condition that can lead to debilitating lower chest and upper abdominal pain (Am J Med Sci 2019; 357: 168). It is caused by hypermobility of the anterior ends of the costal cartilages of false ribs, allowing the eighth to tenth ribs to slip under the rib above, giving its name (Semin Pediatr Surg 2018; 27: 183). Failure to recognize this syndrome can...

article

The adequacy of fluoroscopic upper gastrointestinal studies for suspected intestinal volvulus in a tertiary care centre vs. secondary centres: A regional multicentre study

Kate Amelia Bollard, Gianluca Valsenti, David Healey, Jean Murdoch

Journal of Medical Imaging and Radiation Oncology > 65 > 3 > 293 - 300

Introduction Early diagnosis and treatment of intestinal volvulus are important to reduce morbidity. A fluoroscopic upper GI study is the gold standard for diagnosis and may be performed in a secondary or tertiary care centre prior to surgery. It is important the reporting radiologist is confident in the findings. We aim to assess whether there is any difference in confidence and study quality between...

article

Dental arch relationship outcomes for children with complete unilateral and complete bilateral cleft lip and palate in New Zealand

Peter V. Fowler, Heather Keall, Dan Kennedy, David Healey, more

Orthodontics & Craniofacial Research > 22 > 3 > 147 - 152

Objectives To evaluate dental arch relationships of patients with complete unilateral and complete bilateral cleft lip and palate (CUCLP/CBCLP) in New Zealand. Setting and sample population Retrospective nationwide observational outcomes study involving 100 CUCLP and 32 CBCLP non‐syndromic patients. Material and methods Four calibrated assessors, blinded to the origin of the randomized digital...

article

War in the Chesapeake: The British Campaign to Control the Bay, 1813–14. By Charles Patrick Neimeyer. (Annapolis, MD: Naval Institute Press, 2015. Pp. 256. $44.95.)

David Healey

Historian > 79 > 2 > 347 - 348

chapter

The mechanism by which tmRNA rescues stalled ribosomes

David Healey, Mickey Miller, Christopher Woolstenhulme, Allen Buskirk

Ribosomes > Elongation and ribosome dynamics > 361-373

Not all translation reactions end in the synthesis of a full-length protein. In bacteria, ribosomes stall at the 3′ end of mRNA transcripts lacking stop codons, as they cannot efficiently employ release factors for termination and recycling. Some non-stop mRNAs arise from defects in transcription. RNA polymerase occasionally terminates transcription prematurely; this can occur either as a result of...

article

Perinatal/Neonatal case presentation: pulmonary artery sling associated with respiratory distress

David Healey, Nitin Ron, Andrew Hromada, Manoj Chhabra

SpringerPlus > 2016 > 5 > 1 > 1-4

Pulmonary artery sling is a very rare cause of pediatric respiratory distress. The estimated prevalence of the disease was first determined by Yu et al. in 2008 as 59 per million school-aged children. Associated symptoms are cough, wheezing, and feeding difficulty, all of which are common in routine outpatient pediatric clinical encounters. We report a case of a premature male neonate twin who was...

article

Explants of Intact Endometrium to Model Bovine Innate Immunity and Inflammation Ex Vivo

Álan Maia Borges, Gareth David Healey, Iain Martin Sheldon

American Journal of Reproductive Immunology > 67 > 6 > 526 - 539

ProblemBacterial infections commonly cause bovine endometritis and infertility via innate immune pathways. However, mechanistic studies using isolated cells or chopped tissue may be compromised by the disruption of endometrial architecture and release of damage‐associated molecular patterns. So, this study aimed to establish an ex vivo model of intact bovine endometrium to study innate immunity and...

article

Development and preliminary clinical evaluation of a peptide immunotherapy vaccine for cat allergy

Margitta Worm, Hae-Hyuk Lee, Jörg Kleine-Tebbe, Roderick P. Hafner, more

The Journal of Allergy and Clinical Immunology > 2011 > 127 > 1 > 89-97.e14

Allergic sensitization to cat allergens is common and represents a major risk factor for asthma. Specific immunotherapy (SIT) is effective but cumbersome and associated with IgE-dependent adverse events. Immunotherapy targeting allergen-specific T cells, with synthetic peptides representing T-cell epitopes, might improve safety and reduce the duration of treatment.We sought to define major T-cell...

article

Reduction of Insulin Resistance With Effective Clearance of Hepatitis C Infection: Results From the HALT-C Trial

Aymin Delgado–Borrego, Sergio H. Jordan, Betania Negre, David Healey, more

Clinical Gastroenterology and Hepatology > 2010 > 8 > 5 > 458-462

Hepatitis C virus (HCV) infection is associated with an increased prevalence of diabetes and insulin resistance (IR); whether this is a causal relationship has not been established.We performed a longitudinal study within the lead-in phase of the Hepatitis C Antiviral Long-Term Treatment against Cirrhosis (HALT-C) Trial to evaluate whether suppression of hepatitis C is associated with improvement...

chapter

The academic role in smart grid R&D

David Healey

IET Conference on Smart Grid 2010: Making it a reality > 1 - 20

IET Conference on Smart Grid 2010: Making it a reality

• The Smart Grid Development Centre will be a world-class resource providing a test bed for smart grid technology in a live environment • Opportunities will exist for companies (from SME to major corporates) to deploy, test and showcase smart grid technologies • Supported by academia and industry, the SGDC aims to accelerate the development and deployment of smart grid technologies • We will be inviting...

article

SmpB Contributes to Reading Frame Selection in the Translation of Transfer–Messenger RNA

Talina Watts, DeAnna Cazier, David Healey, Allen Buskirk

Journal of Molecular Biology > 2009 > 391 > 2 > 275-281

Transfer–messenger RNA (tmRNA) acts first as a tRNA and then as an mRNA template to rescue stalled ribosomes in eubacteria. Together with its protein partner, SmpB (small protein B), tmRNA enters stalled ribosomes and transfers an Ala residue to the growing polypeptide chain. A remarkable step then occurs: the ribosome leaves the stalled mRNA and resumes translation using tmRNA as a template, adding...

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