Search results for: Shian Huang

Items from 1 to 20 out of 79 results

article

Sample size determination and treatment screening in two‐stage phase II clinical trials via ROC curve

Wong‐Shian Huang, Yuan‐chin Ivan Chang

Pharmaceutical Statistics > 17 > 5 > 504 - 514

In pharmaceutical‐related research, we usually use clinical trials methods to identify valuable treatments and compare their efficacy with that of a standard control therapy. Although clinical trials are essential for ensuring the efficacy and postmarketing safety of a drug, conducting clinical trials is usually costly and time‐consuming. Moreover, to allocate patients to the little therapeutic effect...

article

Carbon nanotube size effect on the mechanical properties and toughness of nanocomposites

Tsung‐Han Hsieh, Yau‐Shian Huang, Ming‐Yuan Shen

Polymer Composites > 39 > S2 > E1072 - E1086

To evaluate the nanotube size effect on the material properties of nanotube‐modified nanocomposites, two types of multi‐walled carbon nanotubes with various dimensions were used to form nanocomposites, and then the mechanical properties and the toughness were measured. The well‐known issue of nanotube dispersion was examined using various microscopic observations, and an ideal dispersion process was...

article

The spell of cuteness in food consumption? It depends on food type and consumption motivation

Hsiao-Ching Lee, Chun-Tuan Chang, Yu-Hsuan Chen, Yu-Shian Huang

Food Quality and Preference > 2018 > 65 > C > 110-117

Despite the popular use of cuteness in product designs, especially for foods, little is known about how cuteness influences consumption. This article contributes to the evolving stream of research on cuteness by designing two experiments based on the compatibility principle to examine the contextual factors that moderate the effect of cuteness on food consumption (i.e., food type and consumption motivation)...

article

Wound healing

Peng-Hui Wang, Ben-Shian Huang, Huann-Cheng Horng, Chang-Ching Yeh, more

Journal of the Chinese Medical Association > 2018 > 81 > 2 > 94-101

Wound healing is an important physiological process to maintain the integrity of skin after trauma, either by accident or by intent procedure. The normal wound healing involves three successive but overlapping phases, including hemostasis/inflammatory phase, proliferative phase, and remodeling phase. Aberration of wound healing, such as excessive wound healing (hypertrophic scar and keloid) or chronic...

article

Decoy receptor 3 promotes cell adhesion and enhances endometriosis development

Hsiao‐Wen Tsai, Ming‐Ting Huang, Peng‐Hui Wang, Ben‐Shian Huang, more

The Journal of Pathology > 244 > 2 > 189 - 202

Endometriosis is a multifactorial inflammatory disease with persistent activation of the nuclear factor‐κB (NF‐κB) signalling pathway. Aberrant adhesion of endometrium is the essential step in the progression of endometriosis, but the molecular mechanism of ectopic growth of endometrium is still unclear. Decoy receptor 3 (DcR3)/TNFRSF6B, a pleiotropic immunomodulator regulated by oestrogen, is able...

article

Development of the LYVE‐1 gene with an acidic‐amino‐acid‐rich (AAAR) domain in evolution is associated with acquisition of lymph nodes and efficient adaptive immunity

Shuan Shian Huang, Ya‐Wen Li, Jen‐Leih Wu, Frank E. Johnson, more

Journal of Cellular Physiology > 233 > 4 > 2681 - 2692

CRSBP‐1 (mammalian LYVE‐1) is a membrane glycoprotein highly expressed in lymphatic endothelial cells (LECs). It has multiple ligands, including hyaluronic acid (HA) and growth factors/cytokines (e.g., PDGF‐BB and VEGF‐A) containing CRS motifs (clusters of basic amino‐acid residues). The ligand binding activities are mediated by Link module and acidic‐amino‐acid‐rich (AAAR) domains, respectively...

article

Response to comment on “Oestrogen-induced angiogenesis and implantation contribute to the development of parasitic myomas after laparoscopic morcellation”

Ben-Shian Huang, Huann-Cheng Horng, Peng-Hui Wang, Muh-Hwa Yang, more

Reproductive Biology and Endocrinology > 2017 > 15 > 1 > 1-2

According to the literature review, CO2 insufflation on parasitic myoma implantation is not well studied, and we concur that our study is related to “Morcellation-induced parasitic myomas.” We did not compare CO2 insufflation to non-insufflation in our study. The reason is the efficacy of gasless laparoscopic myomectomy and morcellation is not well established and this modality is seldom performed...

article

Postoperative maintenance levonorgestrel-releasing intrauterine system and endometrioma recurrence: a randomized controlled study

Yi-Jen Chen, Teh-Fu Hsu, Ben-Shian Huang, Hsiao-Wen Tsai, more

American Journal of Obstetrics and Gynecology > 2017 > 216 > 6 > 582.e1-582.e9

According to 3 randomized trials, the levonorgestrel-releasing intrauterine system significantly reduced recurrent endometriosis-related pelvic pain at postoperative year 1. Only a few studies have evaluated the long-term effectiveness of the device for preventing endometrioma recurrence, and the effects of a levonorgestrel-releasing intrauterine system as a maintenance therapy remain unclear.The...

article

Simulating painted appearance of BTF materials

Ta-En Chen, Tsung-Shian Huang, Wen-Chieh Lin, Jung-Hong Chuang

Multimedia Tools and Applications > 2018 > 77 > 6 > 7153-7169

Bidirectional texture function (BTF) provides a realistic representation for real-world materials; however, the representation does not allow users to append additional rendering effects to the BTF data in a simple and effective way. In this paper, we present an approach for generating the painted appearance on a material that is represented by a BTF. We first convert a BTF into a physical representation...

article

7‐Dehydrocholesterol (7‐DHC), But Not Cholesterol, Causes Suppression of Canonical TGF‐β Signaling and Is Likely Involved in the Development of Atherosclerotic Cardiovascular Disease (ASCVD)

Shuan Shian Huang, I‐Hua Liu, Chun‐Lin Chen, Jia‐Ming Chang, more

Journal of Cellular Biochemistry > 118 > 6 > 1387 - 1400

For several decades, cholesterol has been thought to cause ASCVD. Limiting dietary cholesterol intake has been recommended to reduce the risk of the disease. However, several recent epidemiological studies do not support a relationship between dietary cholesterol and/or blood cholesterol and ASCVD. Consequently, the role of cholesterol in atherogenesis is now uncertain. Much evidence indicates that...

article

The mechanical properties and delamination of carbon fiber-reinforced polymer laminates modified with carbon aerogel

Tsung-Han Hsieh, Yau-Shian Huang

Journal of Materials Science > 2017 > 52 > 6 > 3520-3534

Carbon aerogels have excellent potential to act as reinforcements for improving the material properties of polymer-based composites because of their porous nanostructures and large surface areas. However, the addition of carbon aerogels to polymer-based composites has effects on the material properties of the final composites, and those effects are not clear. In this study, an epoxy matrix was modified...

article

Women with endometriosis have higher comorbidities: Analysis of domestic data in Taiwan

Sen-Wen Teng, Huann-Cheng Horng, Chi-Hong Ho, Ming-Shyen Yen, more

Journal of the Chinese Medical Association > 2016 > 79 > 11 > 577-582

Endometriosis, defined by the presence of viable extrauterine endometrial glands and stroma, can grow or bleed cyclically, and possesses characteristics including a destructive, invasive, and metastatic nature. Since endometriosis may result in pelvic inflammation, adhesion, chronic pain, and infertility, and can progress to biologically malignant tumors, it is a long-term major health issue in women...

article

Newly diagnosed panic disorder and the risk of erectile dysfunction: A population-based cohort study in Taiwan

Yao-Ting Wang, Hsi-Han Chen, Ching-Heng Lin, Shih-Hsiung Lee, more

Psychiatry Research > 2016 > 244 > C > 229-234

Previous studies indicated that panic disorder is correlated with erectile dysfunction (ED). The primary aim of this study was to explore the incidence rate of ED among panic disorder patients in an Asian country. The secondary aim was to compare the risk of ED in panic disorder patients that were treated with different kinds of antidepressants, and to explore the possible mechanism between these...

article

GW27-e0686 Lowering of mean resting heart rate is associated with less cardiovascular events in bisoprolol-treated Asian patients with coronary artery disease: results from a multinational, observational study

Chen Yundai, Vinh Nguyen Pham, Shian Huang, Dongsoo Kim, more

Journal of the American College of Cardiology > 2016 > 68 > 16(S) > C130-C131

article

Oestrogen-induced angiogenesis and implantation contribute to the development of parasitic myomas after laparoscopic morcellation

Ben-Shian Huang, Muh-Hwa Yang, Peng-Hui Wang, Hsin-Yang Li, more

Reproductive Biology and Endocrinology > 2016 > 14 > 1 > 1-12

Background Iatrogenic parasitic myomas (PMs), caused by intra-corporeal power morcellation during laparoscopy is gradually increasing. However, the pathogenesis and medical treatment of PMs remain largely unelucidated. Methods Laparoscopically-induced PM xenografted mouse model was conducted by xenografting human uterine myoma fragments into the abdominal cavity of SCID mice and hormonal manipulation...

article

Kisspeptin system in female reproduction: A next-generation target in the manipulation of sex hormones

Kuan-Hao Tsui, Ben-Shian Huang, Peng-Hui Wang

Journal of the Chinese Medical Association > 2016 > 79 > 10 > 519-520

article

Uterine sarcoma part III—Targeted therapy: The Taiwan Association of Gynecology (TAG) systematic review

Ming-Shyen Yen, Jen-Ruei Chen, Peng-Hui Wang, Kuo-Chang Wen, more

Taiwanese Journal of Obstetrics and Gynecology > 2016 > 55 > 5 > 625-634

Uterine sarcoma is a very aggressive and highly lethal disease. Even after a comprehensive staging surgery or en block cytoreduction surgery followed by multimodality therapy (often chemotherapy and/or radiation therapy), many patients relapse or present with distant metastases, and finally die of diseases. The worst outcome of uterine sarcomas is partly because of their rarity, unknown etiology,...

article

Uterine sarcoma Part II—Uterine endometrial stromal sarcoma: The TAG systematic review

Yen-Hou Chang, Yi Chang, Hsiang-Tai Chao, Kuan-Chong Chao, more

Taiwanese Journal of Obstetrics & Gynecology > 2016 > 55 > 4 > 472-479

article

Uterine sarcoma Part I—Uterine leiomyosarcoma: The Topic Advisory Group systematic review

Yen-Hou Chang, Yi Chang, Hsiang-Tai Chao, Kuan-Chong Chao, more

Taiwanese Journal of Obstetrics & Gynecology > 2016 > 55 > 4 > 463-471

article

DMSO Enhances TGF‐β Activity by Recruiting the Type II TGF‐β Receptor From Intracellular Vesicles to the Plasma Membrane

Shuan Shian Huang, Chun‐Lin Chen, Franklin W. Huang, Wei‐Hsien Hou, more

Journal of Cellular Biochemistry > 117 > 7 > 1568 - 1579

Dimethyl sulfoxide (DMSO) is used to treat many diseases/symptoms. The molecular basis of the pharmacological actions of DMSO has been unclear. We hypothesized that DMSO exerts some of these actions by enhancing TGF‐β activity. Here we show that DMSO enhances TGF‐β activity by ∼3–4‐fold in Mv1Lu and NMuMG cells expressing Smad‐dependent luciferase reporters. In Mv1Lu cells, DMSO enhances TGF‐β‐stimulated...

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INFONA - science communication portal

Search results for: Shian Huang

Sample size determination and treatment screening in two‐stage phase II clinical trials via ROC curve

Carbon nanotube size effect on the mechanical properties and toughness of nanocomposites

The spell of cuteness in food consumption? It depends on food type and consumption motivation

Wound healing

Decoy receptor 3 promotes cell adhesion and enhances endometriosis development

Development of the LYVE‐1 gene with an acidic‐amino‐acid‐rich (AAAR) domain in evolution is associated with acquisition of lymph nodes and efficient adaptive immunity

Response to comment on “Oestrogen-induced angiogenesis and implantation contribute to the development of parasitic myomas after laparoscopic morcellation”

Postoperative maintenance levonorgestrel-releasing intrauterine system and endometrioma recurrence: a randomized controlled study

Simulating painted appearance of BTF materials

7‐Dehydrocholesterol (7‐DHC), But Not Cholesterol, Causes Suppression of Canonical TGF‐β Signaling and Is Likely Involved in the Development of Atherosclerotic Cardiovascular Disease (ASCVD)

The mechanical properties and delamination of carbon fiber-reinforced polymer laminates modified with carbon aerogel

Women with endometriosis have higher comorbidities: Analysis of domestic data in Taiwan

Newly diagnosed panic disorder and the risk of erectile dysfunction: A population-based cohort study in Taiwan

GW27-e0686 Lowering of mean resting heart rate is associated with less cardiovascular events in bisoprolol-treated Asian patients with coronary artery disease: results from a multinational, observational study

Oestrogen-induced angiogenesis and implantation contribute to the development of parasitic myomas after laparoscopic morcellation

Kisspeptin system in female reproduction: A next-generation target in the manipulation of sex hormones

Uterine sarcoma part III—Targeted therapy: The Taiwan Association of Gynecology (TAG) systematic review

Uterine sarcoma Part II—Uterine endometrial stromal sarcoma: The TAG systematic review

Uterine sarcoma Part I—Uterine leiomyosarcoma: The Topic Advisory Group systematic review

DMSO Enhances TGF‐β Activity by Recruiting the Type II TGF‐β Receptor From Intracellular Vesicles to the Plasma Membrane

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