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To investigate the molecular mechanism of the fast exocytosis at the presynaptic terminal, effects of intracellularly applied synthetic peptides of HPC-1/syntaxin 1A on the autaptic transmission were examined. Hippocampal neurons were cultured on glial micro-islands and singly growing neuron often possessed the autaptic connection. Synthetic peptides (20 a.a., 10 mM), corresponding to various domains...
To investigate the molecular mechanism of the fast exocytosis at the presynaptic terminal, effects of intracellularly applied synthetic peptides of HPC-1/syntaxin 1A on the autaptic transmission were examined. Hippocampal neurons were cultured on glial micro-islands and singly growing neuron often possessed the autaptic connection. Synthetic peptides (20 a.a., 10 mM), corresponding to various domains...