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Kurzfassung Die Erkennung von mikrobiellen Gefahrensignalen durch Makrophagen führt zu ausgeprägten Veränderungen des Zytoskeletts. Die daraus resultierende morphologische Veränderung (Spreading) führt zur Variation der Kontaktfläche zwischen Zellen und Oberflächenmaterial. Bisher wird die Vermessung durch manuelle Annotation einer jeden einzelnen Zelle durchgeführt. Dieser sehr zeitaufwendige Schritt...