Y. Courtois

article

Developmental iron uptake and axonal transport in the retina of the rat

T. Moos, N. Bernth, Y. Courtois, E.H. Morgan

Molecular and Cellular Neuroscience > 2011 > 46 > 3 > 607-613

We examined differently aged postnatal (P) rats for the distribution and uptake of iron in the eye with the main emphasis on iron uptake in the retina. The concentration of iron in the eye was 48μg/g in rats aged one postnatal day (P1). Then concentration fell to approximately 12μg/g at P30 and rose to 35μg/g at P70. Perls' stain which labels both ferrous and ferric iron was found to exhibit a weak...

article

Iontophoresis: from the lab to the bed side

M. Halhal, G. Renard, Y. Courtois, D. BenEzra, more

Experimental Eye Research > 2004 > 78 > 3 > 751-757

Pioneer work on iontophoresis undertaken by David Maurice during the 1970s and 1980s laid the initial groundwork for its potential implementation as a promising ocular therapeutic modality. A better understanding of tissue interactions within the eye during electric current application, along with better designs of drug delivery devices have enabled us to pursue David Maurice's original ideas and...

article

Down-regulation of NOSII gene expression by iontophoresis of anti-sense oligonucleotide in endotoxin-induced uveitis

M. Voigt, Y. de Kozak, M. Halhal, Y. Courtois, more

Biochemical and Biophysical Research Communications > 2002 > 295 > 2 > 336-341

Transcorneoscleral iontophoresis was used to enhance ocular penetration of a 21-bp NH ₂ protected anti-NOSII oligonucleotides (ODNs) (fluorescein or infrared-41 labeled) in Lewis rats. Both histochemical localization and acrylamide sequencing gels were used. To evaluate the potential to down-regulate NOSII expression in the rat model of endotoxin-induced uveitis (EIU), anti-sense NOSII ODN,...

article

Distribution of Proteins Providing Homeostasis of Iron Ions in Bovine Retina

M. G. Yefimova, J.-C. Jeanny, Y. Courtois

Journal of Evolutionary Biochemistry and Physiology > 2002 > 38 > 6 > 700-705

Distribution of proteins providing homeostasis of iron ions in bovine retina was studied by methods of indirect immunohistochemistry, which allowed detection of localization of transferrin, ferritin, and transferrin receptor. In bovine retina, transferrin is revealed in the region of outer and inner segments of photoreceptors and in the external plexiform layer. Distributions of ferritin and transferrin...

article

Iron and other elements (Cu, Zn, Ca) contents in retina of rats during development and hereditary retinal degeneration

C Sergeant, Y Llabador, G Devès, M.H Vesvres, more

Nuclear Inst. and Methods in Physics Research, B > 2001 > 181 > 1-4 > 533-538

The retina as well as other tissues needs iron to survive, but modifications in iron metabolism have also been suggested to contribute to cerebral neurodegenerative diseases. Our study was intended to investigate iron distribution in the retina of normal rats and Royal College of Surgeons (RCS) rats affected by hereditary degeneration of the photoreceptors at different developmental stages (35, 45...

article

Semiclassical Monte Carlo approaches for realistic atoms in optical lattices

K. I. Petsas, G. Grynberg, J.-Y. Courtois

The European Physical Journal D > 1999 > 6 > 1 > 29-47

Abstract: We present two different numerical approaches, based on semiclassical Monte Carlo simulations, for the study of optical lattices associated with atomic transitions, for angular momenta and larger than . Our models rely on an adiabatic-type approximation and give a correct description of the steady-state temperature and localization properties of the lattice, in a large range of parameters...

article

Recoil and momentum diffusion of an atom close to a vacuum-dielectric interface

C. Henkel, J.-Y. Courtois

The European Physical Journal D > 1998 > 3 > 2 > 129-153

Abstract: We derive the quantum-mechanical master equation (generalized optical Bloch equation) for an atom in the vicinity of a flat dielectric surface. This equation gives access to the semiclassical radiation pressure force and the atomic momentum diffusion tensor, that are expressed in terms of the vacuum field correlation function (electromagnetic field susceptibility). It is demonstrated that...

article

Spontaneous light scattering from propagating density fluctuations in an optical lattice

C. Jurczak, J.-Y. Courtois, B. Desruelle, C.I. Westbrook, more

The European Physical Journal D > 1998 > 1 > 1 > 53-56

Abstract: We report the observation of resonances in the intensity correlation spectra of a 3D rubidium optical lattice, which we attribute to light scattering from propagating atomic density fluctuations in the lattice. This process is the spontaneous analog of the stimulated scattering mechanism recently described by Courtois et al.. We investigate the dependence of the new resonances on the lattice...

article

Bright optical lattices in a longitudinal magnetic field. Experimental study of the oscillating and jumping regimes

C. Mennerat-Robilliard, L. Guidoni, K.I. Petsas, P. Verkerk, more

The European Physical Journal D > 1998 > 1 > 1 > 33-45

Abstract: All the bright optical lattices studied so far have been designed to obtain a circularly polarized light at the bottom of the optical potential wells. This condition minimizes the departure rate of the atoms from the fundamental adiabatic surface and permits an oscillating regime in a large range of parameters. We present here an experimental study of cesium atoms in a three-dimensional...

article

Stability study of cefepime in different infusion solutions

Sylvie M. Rabouan-Guyon, Agnès F. Guet, Philippe Y. Courtois, Danièle M.C. Barthes

International Journal of Pharmaceutics > 1997 > 154 > 2 > 185-190

The stability of cefepime in the formulation Axepim diluted with 0.9% sodium chloride or with 5% glucose in a three layer laminate bag Clear-Flex (polyethylene container) was investigated at 24 ± 2°C in daylight and at 4 ± 2°C in the dark (initial concentration was 8 mg ml ^- ¹ ). Stability was defined as at least 90% of the initial concentration. Analyses were performed...

article

Nitric Oxide in the Eye: Multifaceted Roles and Diverse Outcomes

F. Becquet, Y. Courtois, O. Goureau

Survey of Ophthalmology > 1997 > 42 > 1 > 71-82

Recent works have highlighted the role of nitric oxide in a wide array of disease entities, including septic shock, hypertension, cerebral ischemia, and chronic degenerative diseases of the nervous system. The functions of nitric oxide appear very diverse, having actions on vascular tone, neurotransmission, immune cytotoxicity, and many others. Nitric oxide is an important mediator of homeostatic...

article

On the use of Zn ² ⁺ to discriminate endonucleases activated during apoptosis

A Torriglia, E Chaudun, Y Courtois, MF Counis

Biochimie > 1997 > 79 > 7 > 435-438

One approach to discriminate among specific DNases in apoptosis is to use inhibitors specific for each endonuclease. Zn ² ⁺ is known to inhibit Ca ² ⁺ - and Mg ² ⁺ -dependent endonuclease enzymatic activities during apoptosis. Acidic DNases were thought to be insensitive to Zn ² ⁺ . In this paper, we analyse the effects of Zn ² ⁺ on activity...

chapter

Van Der Waals Force In An Evanescent Wave Atomic Mirror

A. Aspect, A. Landragin, J.-Y. Courtois, G. Labeyrie, more

QELS '97., Summaries of Papers Presented at the Quantum Electronics and Laser Science Conference > 54

QELS '97., Summaries of Papers Presented at the Quantum Electronics and Laser Science Conference

article

Expression and Regulation by Serum of Multiple FGF1 mRNA in Normal Transformed, and Malignant Human Mammary Epithelial Cells

F. Renaud, I. El Yazidi, Y. Boilly-Marer, Y. Courtois, more

Biochemical and Biophysical Research Communications > 1996 > 219 > 3 > 679-685

In normal (NMEC), transformed (HBL-100) and malignant human mammary epithelial cells (MCF 7, BT-20, MDA-MB 231), we have examined the expression and the regulation by serum of FGF1 and FGF2 mRNA. FGF2 mRNA level was higher in NMEC and in a HBL-100 than in malignant cell lines (MDA-MB-231, BT-20). No FGF2 mRNA was detected in the malignant cell line, MCF-7. In contrast, the FGF1 mRNA was detected in...

article

Effects of intraocular injection of no donnors in the rabbit

F. Behar-Cohen, O. Goureau, F. D'Hermie, Y. Courtois

Vision Research > 1995 > 35 > Supplement 1; Supplement > S62

Purpose: Nitric Oxyde (NO) is synthesized by two types of NO synthases: A constitutive isoforme (cNOS) which activity is calcium-calmodulin dependent, and an inducible one (iNOS), regulated by cytokines and stimulated by lipopolysacharide (LPS). NOSc activity has been demonstrated in the ciliary body, in the choroid, and in the retina (amacrines cells, RPE and ROS). NO could be implicated in the...

article

Effects of intraocular injection of no donnors in the rabbit.

F. Behar-Cohen, O. Goureau, F. D'Hermie, Y. Courtois

Vision Research > 1995 > 35 > Supplement 1; Supplement > S191

Purpose: Nitric Oxyde (NO) is synthesized by two types of NO synthases: A constitutive isoforme (cNOS) which activity is calcium-calmodulin dependent, and an inducible one (iNOS), regulated by cytokines and stimulated by lipopolysacharide (LPS). NOSc activity has been demonstrated in the ciliary body, in the choroid, and in the retina (amacrines cells, RPE and ROS). NO could be implicated in the...

article

Role of immunoregulatory cytokines TGF-β, IL-4, IL-10, in the in vitro production of TNF and no by retinal resident cells

Y de Kozak, MC Naud, O Goureau, Y Courtois, more

Vision Research > 1995 > 35 > Supplement 1; Supplement > S114

Purpose: We have previously shown that cultured retinal M:ller glia (RMG) and retinal pigmented epithelium (RPE) isolated from Lewis rat and stimulated by lipopolysaccharide (LPS) and interferon (IFN)-γ release large amounts of tumor necrosis factor (TNF) and nitric oxide (NO). Ocular models of inflammation (S-antigen-induced experimental autoimmune uveoretinitis, EAU and endotoxin-induced uveitis,...

article

Basic fibroblast growth factor (bFGF) in corneal storage media protects endothelial cells from damage caused by toxic agents

P. Rieck, R. Kessen, CHR. Hartmann, Y. Courtois

Vision Research > 1995 > 35 > Supplement 1; Supplement > S159

Purpose: We have previously shown that bFGF added to corneal storage media is able to prolong endothelial viability and thus, storage time of the cornea (IOVS 1993). In the present study, we investigated whether the presence of bFGF in the medium could protect the endothelium from damage of toxic agents. Methods: Fresh bovine corneas were stored in a modified Dexsol medium at 4 ^o C for 14...

article

Impact des conditions de conduite sur l'efficacite des pots catalytiques de vehicules a essence et diesel

Ph. Pornet, C. Beaubestre, Y. Courtois, B. Festy, more

Science of the Total Environment > 1995 > 169 > 1-3 > 321-329

Various driving conditions determine major changes in IC-engined vehicles polluting emissions. The generalized use of three-way catalysts on gasoline-engined vehicles and, in the near future, oxidation catalysts on diesel-engined vehicles, is likely to enable the control of such changes. Thus, the influence of driving conditions on the efficiency of such devices was studied in a research program...

article

Spatial and temporal expression patterns of FGF receptor genes type 1 and type 2 in the developing chick retina

M. Tcheng, G. Fuhrmann, M. P. Hartmann, Y. Courtois, more

Ophthalmic Literature > 1995 > 48 > 2 > 125

Fibroblast growth factors are known to influence the growth and differentiation of cultured cells derived from the chick retina. The fibroblast growth factors can interact with a family of at least four closely related receptor kinases. To find a correlation between the presence of fibroblast growth factor receptors and eye development, the patterns of expression of transcripts encoding the type...

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Search results for: Y. Courtois

Developmental iron uptake and axonal transport in the retina of the rat

Iontophoresis: from the lab to the bed side

Down-regulation of NOSII gene expression by iontophoresis of anti-sense oligonucleotide in endotoxin-induced uveitis

Distribution of Proteins Providing Homeostasis of Iron Ions in Bovine Retina

Iron and other elements (Cu, Zn, Ca) contents in retina of rats during development and hereditary retinal degeneration

Semiclassical Monte Carlo approaches for realistic atoms in optical lattices

Recoil and momentum diffusion of an atom close to a vacuum-dielectric interface

Spontaneous light scattering from propagating density fluctuations in an optical lattice

Bright optical lattices in a longitudinal magnetic field. Experimental study of the oscillating and jumping regimes

Stability study of cefepime in different infusion solutions

Nitric Oxide in the Eye: Multifaceted Roles and Diverse Outcomes

On the use of Zn ² ⁺ to discriminate endonucleases activated during apoptosis

Van Der Waals Force In An Evanescent Wave Atomic Mirror

Expression and Regulation by Serum of Multiple FGF1 mRNA in Normal Transformed, and Malignant Human Mammary Epithelial Cells

Effects of intraocular injection of no donnors in the rabbit

Effects of intraocular injection of no donnors in the rabbit.

Role of immunoregulatory cytokines TGF-β, IL-4, IL-10, in the in vitro production of TNF and no by retinal resident cells

Basic fibroblast growth factor (bFGF) in corneal storage media protects endothelial cells from damage caused by toxic agents

Impact des conditions de conduite sur l'efficacite des pots catalytiques de vehicules a essence et diesel

Spatial and temporal expression patterns of FGF receptor genes type 1 and type 2 in the developing chick retina

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