Search results for: Izabela Korona-Glowniak

Items from 1 to 13 out of 13 results

article

CAPE derivatives: Multifaceted agents for chronic wound healing

Marwa Balaha, Amelia Cataldi, Alessandra Ammazzalorso, Ivana Cacciatore, more

Archiv der Pharmazie > 357 > 10 > n/a - n/a

Chronic wounds significantly impact the patients' quality of life, creating an urgent interdisciplinary clinical challenge. The development of novel agents capable of accelerating the healing process is essential. Caffeic acid phenethyl ester (CAPE) has demonstrated positive effects on skin regeneration. However, its susceptibility to degradation limits its pharmaceutical application. Chemical modification...

article

Phytochemical composition of wormwood (Artemisia gmelinii) extracts in respect of their antimicrobial activity

Aliya S. Mamatova, Izabela Korona-Glowniak, Krystyna Skalicka-Woźniak, Aleksandra Józefczyk, more

BMC Complementary and Alternative Medicine > 2019 > 19 > 1 > 1-8

Background Extracts from medicinal plants with phytochemicals with known antimicrobial properties can be an effective adjunct in the complex treatment of infectious diseases. This study aimed to evaluate the antimicrobial activity of wormwood extracts collected in Kazakhstan (Artemisia gmelinii Weber ex Stechm.), along with their phytochemical analysis. Methods The ethanolic and chloroform extracts...

article

Resistant Streptococcus pneumoniae strains in children with acute otitis media– high risk of persistent colonization after treatment

Izabela Korona-Glowniak, Piotr Zychowski, Radoslaw Siwiec, Elżbieta Mazur, more

BMC Infectious Diseases > 2018 > 18 > 1 > 1-11

Background Despite advances in the development of pneumococcal conjugate vaccines, acute otitis media (AOM) is a common childhood infection, caused mainly by Streptococcus pneumoniae. It has been suggested that persistence of pneumococcal nasopharyngeal carriage is a risk factor for subsequent recurrent infections. Methods In this study we evaluate the relationship between 55 pneumococcal strains...

article

In vitro susceptibility of oral Candida albicans isolates to chlorhexidine

Anna Biernasiuk, Jolanta Szymańska, Agata Kustra, Izabela Korona-Głowniak, more

Acta Poloniae Pharmaceutica - Drug Research > 2018 > 75 > 3

Fungal infections are an important medical problem in patients from different risk groups. The majority of these infections are caused by Candida spp., with over 50 % due to C. albicans. The purpose of the study was to evaluate in vitro chlorhexidine effect on C. albicans colonizing the mouth and throat isolated from 5 population groups. The study material included the reference strains of C. albicans...

article

Structural analysis and antimicrobial activity of 2[1H]-pyrimidinethione/selenone derivatives

Ewa Żesławska, Izabela Korona-Głowniak, Małgorzata Szczesio, Andrzej Olczak, more

Journal of Molecular Structure > 2017 > 1142 > C > 261-266

Four new crystal structures of sulfur and selenium analogues of 2[1H]-pyrimidinone derivatives were determined with the use of X-ray diffraction method. The molecular geometry and intermolecular interactions of the investigated molecules were analyzed in order to find the structural features and geometrical parameters, which can be responsible for antimicrobial activities. The influence of chalcogen...

article

The PD-1/PD-L1 Inhibitory Pathway is Altered in Primary Glomerulonephritides

Ewelina Grywalska, Iwona Smarz-Widelska, Ewelina Krasowska-Zajac, Izabela Korona-Glowniak, more

Archivum Immunologiae et Therapiae Experimentalis > 2018 > 66 > 2 > 133-143

The pathogenesis of primary proliferative and non-proliferative glomerulonephritides (PGN and NPGN) is still not fully understood, however, current evidence suggests that most cases of PGN and NPGN are the results of immunologic response to different etiologic agents that activates various biological processes leading to glomerular inflammation and injury. Programmed cell death protein 1 (PD-1) is...

article

Antibacterial properties of 5-substituted derivatives of rhodanine-3-carboxyalkyl acids

Waldemar Tejchman, Izabela Korona-Glowniak, Anna Malm, Marek Zylewski, more

Medicinal Chemistry Research > 2017 > 26 > 6 > 1316-1324

A series of rhodanine 3-carboxyalkanoic acid derivatives possessing 4′-(N,N-dialkyl-amino or diphenylamino)-benzylidene moiety as a substituent at the C-5 position were synthesised and their antibacterial activity was screened. All the rhodanine derivatives showed bacteriostatic or bactericidal activity to the reference gram-positive bacterial strains, but lack of activity to the reference Gram-negative...

article

Iodine in autism spectrum disorders

Anna Błażewicz, Agata Makarewicz, Izabela Korona-Glowniak, Wojciech Dolliver, more

Journal of Trace Elements in Medicine and Biology > 2016 > 34 > C > 32-37

The aim of our study was to assess the iodine status of Polish boys with severe autism compared to their healthy peers and evaluate the relationship between urinary iodine, thyroid hormones, body mass index and Autism Spectrum Disorder (ASD) symptomatology.Tests were performed in 40 boys with ASD and 40 healthy boys, aged 2–17 from the same geographic region in Poland. Urinary iodine (UI), free triiodothyronine...

article

Anti-Helicobacter pylori activity in vitro of chamomile flowers, coneflower herbs, peppermint leaves and thyme herbs – a preliminary report

Anna Malm, Anna Glowniak-Lipa, Izabela Korona-Glowniak, Tomasz Baj

Current Issues in Pharmacy and Medical Sciences > 2015 > 28 > 1 > 30-32

Recently, several studies have been undertaken so as to develop more effective therapeutic approaches towards eradicating Helicobacter pylori. Among these is phytotherapy. The aim of this study was to investigate the activity in vitro of the plant extracts obtained from common herbs cultivated in the Lubelszczyzna region against the reference strain H. pylori ATCC 43504. Among these are thyme herbs,...

article

Serum and urinary selenium levels in obese children: A cross-sectional study

Anna Błażewicz, Maria Klatka, Aleksander Astel, Izabela Korona-Glowniak, more

Journal of Trace Elements in Medicine and Biology > 2015 > 29 > Complete > 116-122

To determine serum and urinary selenium (Se) levels in children with and without obesity, and to assess if Se influences the risk of obesity.High-resolution-continuum source-atomic absorption spectrometry (HR-CS-AAS) was used to determine the content of Se in 80 children (age 6–17; 40 boys, 40 girls). Correlations between variables were tested with the use of Spearman's correlation coefficient. U...

article

Differentiation by random amplified polymorphic DNA-polymerase chain reaction (RAPD-PCR) of Candida albicans isolated from upper respiratory tract in patients with non-small cell lung cancer

Anna Biernasiuk, Izabela Korona-Głowniak, Agnieszka Grzegorczyk, Anna Malm

Acta Biochimica Polonica > 2014 > 61 > 4 > 727-729

Cancer patients are predisposed to fungal infections caused by Candida albicans, especially to oral or respiratory tract candidiasis. The aim of this study was to estimate genetic diversity by RAPD-PCR (random amplified polymorphic DNA-polymerase chain reaction) of C. albicans isolated from upper respiratory tract of 100 patients with non-small cell lung cancer. Among 52 strains, 34 genotypes were...

article

Distribution of vaccine serotypes among Streptococcus pneumoniae colonizing the upper respiratory tract in healthy pre-school children in south-east Poland

Artur Niedzielski, Izabela Korona-Głowniak, Anna Malm, Grażyna Mielnik-Niedzielska

Otolaryngologia Polska > 2012 > 66 > 6 > 403-406

Studies on the distribution of Streptococcus pneumoniae serotypes associated with colonization of the upper respiratory tract in young children are currently of general interest because of the impact of the new pneumococcal conjugate vaccines (PCV) on carriage of pneumococci and the incidence of pneumococcal disease.Therefore, we evaluated the coverage of 10-valent PCV (PCV10) as well as 13-valent...

article

Upper respiratory colonization by Streptococcus pneumoniae in healthy pre-school children in south-east Poland

Izabela Korona-Glowniak, Artur Niedzielski, Anna Malm

International Journal of Pediatric Otorhinolaryngology > 2011 > 75 > 12 > 1529-1534

Carriage of Streptococcus pneumoniae in upper respiratory tract of healthy children is a major factor in the horizontal transmission of pneumococcal strains, especially between children attending day-care centers and may be also the source of infection in other individuals. During 8-month prospective study including 3 seasons (autumn, winter, spring), we determined risk factors for S. pneumoniae colonization...

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Keywords

STREPTOCOCCUS PNEUMONIAE (3)
ANTIBACTERIAL ACTIVITY (2)
ANTIBIOTIC RESISTANCE (2)
CANDIDA ALBICANS (2)
RISK FACTORS (2)
2[1H]-PYRIMIDINESELENONE (1)
2[1H]-PYRIMIDINETHIONE (1)
ACUTE OTITIS MEDIA (1)
ANTI-HELICOBACTER PYLORI ACTIVITY (1)
ANTIBACTERIALS (1)
ANTIFUNGAL AGENTS (1)
ANTIFUNGALS (1)
ANTIMICROBIAL ACTIVITY (1)
ARTEMISIA GMELINII (1)
ASTERACEAE (1)
AUTISM (1)
CAPE (1)
CHAMOMILE FLOWERS (1)
CHILDHOOD OBESITY, BODY FLUIDS (1)
CHLORHEXIDINE (1)
CONEFLOWER HERBS (1)
CRYSTAL STRUCTURE (1)
GENETIC DIVERSITY (1)
GLOMERULONEPHRITIS (1)
HR-CS-AAS (1)
IGA NEPHROPATHY (1)
IMMUNOLOGY (1)
IMMUNOSUPPRESSION (1)
IODINE (1)
ION CHROMATOGRAPHY (1)
ISOSTRUCTURAL CRYSTAL PACKING (1)
MEMBRANOPROLIFERATIVE GLOMERULONEPHRITIS (1)
MINIMAL CHANGE DISEASE (1)
MLST (1)
PEPPERMINT LEAVES (1)
PHYTOCHEMICAL ANALYSIS (1)
PNEUMOCOCCAL VACCINES (1)
RAPD-PCR (1)
RHODANINE (1)
RHODANINE-3-ACETIC ACID (1)
ROS (1)
SELENIUM (1)
SEROTYPES (1)
SEROTYPY (1)
STABILITY (1)
SZCZEPIONKA PNEUMOKOKOWA (1)
THIAZOLIDINE-4-ONE (1)
THYME HERBS (1)
UPPER RESPIRATORY COLONIZATION (1)
UPPER RESPIRATORY TRACT (1)
URINE (1)
WOUND HEALING (1)
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Elsevier (5)
Springer (4)
PSJD (3)
Wiley (1)

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