Search results for: Wolf-Dietrich Huber

Items from 1 to 20 out of 20 results

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Golimumab in adolescents with Crohn's disease refractory to previous tumour necrosis factor antibody

Judith Pichler, Nima Memaran, Wolf Dietrich Huber, Christoph Aufricht, more

Aim Anti‐tumour necrosis factor (TNF)‐α drugs are effective treatments for the management of moderate/severe Crohn's disease (CD), but treatment failure is common. In the treatment of paediatric CD, there are no data about the use of a third introduced subcutaneous TNF antibody golimumab. Methods We evaluated the efficacy of golimumab for adolescents with moderate/severe CD. Retrospective analyses...

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Development and validation of the paediatric Carbohydrate Perception Questionnaire (pCPQ), an instrument for the assessment of carbohydrate‐induced gastrointestinal symptoms in the paediatric population

Johann Hammer, Nima Memaran, Wolf‐Dietrich Huber, Karin Hammer

Neurogastroenterology & Motility > 32 > 12 > n/a - n/a

Background There is an unmet need for a validated, test‐specific symptom questionnaire to evaluate carbohydrate perception during breath tests. Our aim was to develop and validate a questionnaire for the assessment of symptoms after a provocative carbohydrate load. Methods After a literature search and initial focus group‐style interviews, five relevant complaints were identified. Responses were...

article

Vedolizumab use after failure of TNF-α antagonists in children and adolescents with inflammatory bowel disease

Anna-Maria Schneider, Daniel Weghuber, Benjamin Hetzer, Andreas Entenmann, more

BMC Gastroenterology > 2018 > 18 > 1 > 1-7

Background Vedolizumab is safe and effective in adult patients with Crohn’s disease (CD) and ulcerative colitis (UC); however, data in children with inflammatory bowel disease (IBD) are scarce. Therefore, we evaluated vedolizumab use in a cohort of Austrian paediatric patients with IBD. Methods Twelve patients (7 female; 7 CD; 5 UC), aged 8–17 years (median, 15 years), with severe IBD who received...

article

Correction to: Relationship Between Abdominal Symptoms and Fructose Ingestion in Children with Chronic Abdominal Pain

Veronika Hammer, Katharina Hammer, Nima Memaran, Wolf-Dietrich Huber, more

Digestive Diseases and Sciences > 2018 > 63 > 6 > 1670-1670

The original version of this article unfortunately contained an error in a couple of reference citation in Discussion Section, paragraph 6. The reference citation number should be changed from [6] to [9] in the below sentences so that it reads.

article

Relationship Between Abdominal Symptoms and Fructose Ingestion in Children with Chronic Abdominal Pain

Veronika Hammer, Katharina Hammer, Nima Memaran, Wolf-Dietrich Huber, more

Digestive Diseases and Sciences > 2018 > 63 > 5 > 1270-1279

Background Limited valid data are available regarding the association of fructose-induced symptoms, fructose malabsorption, and clinical symptoms. Aim To develop a questionnaire for valid symptom assessment before and during a carbohydrate breath test and to correlate symptoms with fructose breath test results in children/adolescents with functional abdominal pain. Methods A Likert-type questionnaire...

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Coeliac disease in adolescence: Coping strategies and personality factors affecting compliance with gluten-free diet

Gudrun Wagner, Michael Zeiler, Vasileia Grylli, Gabriele Berger, more

Appetite > 2016 > 101 > C > 55-61

Patients suffering from a chronic condition such as coeliac disease (CD) need to develop coping strategies in order to preserve emotional balance and psychosocial functioning while adhering to their obligatory life-long gluten free diet (GFD). However, this can be particularly challenging for adolescents and may lead to dietary transgressions. Little is currently known about the influence of coping...

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Usefulness of recombinant γ-gliadin 1 for identifying patients with celiac disease and monitoring adherence to a gluten-free diet

Bharani Srinivasan, Margarete Focke-Tejkl, Milena Weber, Sandra Pahr, more

Journal of Allergy and Clinical Immunology > 2015 > 136 > 6 > 1607-1618.e3

Celiac disease (CD) is an inflammatory disease of the small intestine caused by an immunologic hypersensitivity reaction to dietary wheat gluten.We sought to clone, express, and perform IgA epitope mapping of a CD-specific wheat antigen and to study its usefulness for identifying patients with CD and monitoring adherence to a gluten-free diet.A synthetic gene coding for γ-gliadin 1 (GG1) was expressed...

article

Eating Disorders in Adolescents with Celiac Disease: Influence of Personality Characteristics and Coping

Gudrun Wagner, Michael Zeiler, Gabriele Berger, Wolf‐Dietrich Huber, more

European Eating Disorders Review > 23 > 5 > 361 - 370

ObjectivesPatients suffering from celiac disease (CD) have a higher risk of developing disturbed eating behaviour. MethodIn a multi‐centre study, 259 female adolescents with CD and without a chronic condition were analysed regarding their eating disorder (ED) status, depression, personality, coping strategies and quality of life. ResultsPatients with CD and comorbid EDs were older and more often...

article

Prevalence, clinical investigation, and management of gallbladder disease in Rett syndrome

Michael Freilinger, Michael Böhm, Ines Lanator, Klara Vergesslich‐Rothschild, more

Developmental Medicine & Child Neurology > 56 > 8 > 756 - 762

AimThis study determined the prevalence of cholelithiasis and/or cholecystectomy in Rett syndrome, described gallbladder function in a clinical cohort, and identified recommendations for assessment and management of gallbladder disease. MethodThe incidence of cholelithiasis/cholecystectomy was estimated from data describing 270 and 681 individuals with a pathogenic MECP2 mutation in the Australian...

article

Paediatric patients with inflammatory bowel disease who received infliximab experienced improved growth and bone health

Judith Pichler, Andreas Hanslik, Wolf Dietrich Huber, Christoph Aufricht, more

Acta Paediatrica > 103 > 2 > e69 - e75

AimChildren with inflammatory bowel disease (IBD) have a high prevalence of growth retardation and low bone mineral density (BMD). This retrospective study investigated whether the start of infliximab treatment (IFX) was associated with improvement of growth and bone health. MethodsAnthropometry, BMD and bone markers were measured 1 year before and after the start of IFX treatment in 33 patients...

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A combined biochemical, biophysical and immunological approach towards the identification of celiac disease-specific wheat antigens

Bharani Srinivasan, Margarete Focke-Tejkl, Ines Swoboda, Claudia Constantin, more

Amino Acids > 2013 > 45 > 4 > 889-900

Celiac disease (CD) is an inflammatory affliction of the small bowel caused by an immunological hypersensitivity to ingested wheat antigens affecting almost 1 % of the population. The gliadin fraction of wheat has been shown to contain the pathogenic antigens which react with antibodies and T cells. However, there is only limited knowledge regarding the precise nature of the wheat antigens recognized...

article

Time Trends of Helicobacter pylori Resistance to Antibiotics in Children Living in Vienna, Austria

Andreas Vécsei, Andrea Kipet, Albina Innerhofer, Ulrike Graf, more

Helicobacter > 15 > 3 > 214 - 220

Background: Increase of antibiotic resistance is a worldwide problem. Within the 4 years before the turn of the millennium Helicobacter pylori strains isolated in children living in Vienna, Austria, showed a primary clarithromycin and metronidazole resistance of 20% and 16%, respectively. The aim of this retrospective follow‐up survey was to assess the further development and current antimicrobial...

article

High sustained virologic response rates in children with chronic hepatitis C receiving peginterferon alfa-2b plus ribavirin

Stefan Wirth, Carmen Ribes-Koninckx, Maria Angeles Calzado, Flavia Bortolotti, more

Journal of Hepatology > 2010 > 52 > 4 > 501-507

Pegylated interferon (PEG-IFN) alfa-2b plus ribavirin (RBV) is the standard of care for adults with chronic hepatitis C but was not approved for the treatment of children at the time of this study. The aim of this study was to evaluate the efficacy and safety of PEG-IFN alfa-2b plus RBV in children.Children and adolescents ages 3–17years were treated with PEG-IFN alfa-2b (60μg/m ² /week) plus...

article

4. Österreichischer Konsensusbericht zur Diagnose und Therapie der Hepatitis B 2009

Markus Peck-Radosavljevic, Johann Deutsch, Peter Ferenci, Ivo Graziadei, more

Wiener klinische Wochenschrift > 2010 > 122 > 9-10 > 280-302

Die Hepatitis B ist die häufigste chronische Virusinfektion der Leber. Sie betrifft zumindest geschätzte 350 Millionen Menschen weltweit und ist die häufigste leberbedingte Todesursache. In der letzten Zeit gab es dramatische Entwicklungen sowohl in der Diagnostik als auch in der Medikamentenentwicklung der chronischen Hepatitis B. Heute ist die chronische Hepatitis B in der überwiegenden Mehrzahl...

article

Eating Pathology in Adolescents With Celiac Disease

Andreas Karwautz, Gudrun Wagner, Gabriele Berger, Ursula Sinnreich, more

Psychosomatics > 2008 > 49 > 5 > 399-406

Celiac disease (CD), treated by a gluten-free diet, may represent a nonspecific trigger for the development of eating pathology, particularly in adolescence.The authors sought to perform a systematic study on eating pathology in CD.CD patients were assessed for eating disorders by questionnaire, and body mass index was recorded.There was a higher rate of eating pathology in CD patients than would...

article

Serological screening for undiagnosed coeliac disease in male adolescents in Lower Austria

Claudia Edlinger-Horvat, Doris Fidler, Wolf-Dietrich Huber, Birgit Rami, more

European Journal of Pediatrics > 2005 > 164 > 1 > 52-53

article

Acrodermatitis enteropathica-like eruption as the presenting sign of cystic fibrosis case report and review of the literature

Julia Crone, Wolf-Dietrich Huber, Irmgard Eichler, Gerhard Granditsch

European Journal of Pediatrics > 2002 > 161 > 9

Abstract. In most patients with cystic fibrosis (CF), pulmonary symptoms are the first sign of presentation. Another predominant feature is maldigestion, frequently starting in early childhood. Pancreatic exocrine dysfunction causes maldigestion, characterised by failure to thrive, diarrhoea, hypoproteinaemia, oedema and anaemia. Dermatitis may be the initial manifestation in just a few patients with...

article

Acrodermatitis enteropathica-like eruption as the presenting sign of cystic fibrosis – case report and review of the literature

Julia Crone, Wolf-Dietrich Huber, Irmgard Eichler, Gerhard Granditsch

European Journal of Pediatrics > 2002 > 161 > 9 > 475-478

In most patients with cystic fibrosis (CF), pulmonary symptoms are the first sign of presentation. Another predominant feature is maldigestion, frequently starting in early childhood. Pancreatic exocrine dysfunction causes maldigestion, characterised by failure to thrive, diarrhoea, hypoproteinaemia, oedema and anaemia. Dermatitis may be the initial manifestation in just a few patients with CF. We...

article

Interventional stent implantation in a child with patent ductus venosus and pulmonary hypertension

Manfred Marx, Wolf-Dietrich Huber, Julia Crone, Johannes Lammer, more

European Journal of Pediatrics > 2001 > 160 > 8 > 501-504

AbstractWe report on the rare case of a 4-year-old boy with patent ductus venosus and pulmonary hypertension presenting with progressive fatigue, tachypnoea at rest and tachycardia. Cardiac catheterisation revealed suprasystemic pressure in the pulmonary arteries with severely elevated pulmonary vascular resistance. In order to reduce the diameter of the ductus venosus, a stent was implanted interventionally,...

article

Budd-Chiari syndrome associated with coagulation abormalities in a child with carbohydrate deficient glycoprotein syndrome type Ix

Martina Huemer, Wolf-Dietrich Huber, Wolfgang Schima, Dorothea Moeslinger, more

The Journal of Pediatrics > 2000 > 136 > 5 > 691-695

A 6-year-old male patient presented with Budd-Chiari syndrome and glyco-protein abnormalities associated with carbohydrate deficient glycoproteln syndrome type I with yet unidentified molecular defect (type Ix). Budd-Chiari syndrome most likely developed after hepatic venous thrombosis caused by coagulation abnormalities resulting from hypoglycosylation and functional impairment of anticoagulant proteins.

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